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Metopirone (Metyrapone) - Side Effects and Adverse Reactions

 
 



ADVERSE REACTIONS

Cardiovascular System: Hypotension.
Gastrointestinal System: Nausea, vomiting, abdominal discomfort or pain.
Central Nervous System: Headache, dizziness, sedation.
Dermatologic System: Allergic rash.
Hematologic System: Rarely, decreased white blood cell count or bone marrow depression.



REPORTS OF SUSPECTED METOPIRONE SIDE EFFECTS / ADVERSE REACTIONS

Below is a sample of reports where side effects / adverse reactions may be related to Metopirone. The information is not vetted and should not be considered as verified clinical evidence.

Possible Metopirone side effects / adverse reactions in 48 year old female

Reported by a physician from Japan on 2011-10-10

Patient: 48 year old female

Reactions: Gamma-Glutamyltransferase Increased, Alanine Aminotransferase Increased, Aspartate Aminotransferase Increased, Liver Function Test Abnormal

Suspect drug(s):
Metopirone
    Dosage: 3000 mg,daily
    Administration route: Oral
    Start date: 2011-09-08
    End date: 2011-09-12

Metopirone
    Dosage: 1500 mg, daily
    Administration route: Oral
    Start date: 2011-09-13

Lansoprazole
    Dosage: 30 mg, daily
    Administration route: Oral
    Start date: 2011-09-06
    End date: 2011-09-12

Metopirone
    Dosage: 1500 mg, daily
    Administration route: Oral
    Indication: Cushing's Syndrome
    Start date: 2011-09-03
    End date: 2011-09-03

Metopirone
    Dosage: 750 to 1500 mg, daily
    Administration route: Oral
    Start date: 2011-09-06
    End date: 2011-09-07

Other drugs received by patient: Decadron; Famotidine



Possible Metopirone side effects / adverse reactions in 51 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-01-18

Patient: 51 year old female weighing 116.0 kg (255.2 pounds)

Reactions: Multi-Organ Failure, Diarrhoea, Hypotension, Adrenal Insufficiency, Hypoxia, Lactic Acidosis, Pulseless Electrical Activity

Adverse event resulted in: hospitalization

Suspect drug(s):
Metopirone

Torisel
    Dosage: last dose:01nov2011
    Indication: Neoplasm
    Start date: 2011-10-03

Ixempra KIT
    Dosage: last dose:24oct2011
    Indication: Neoplasm
    Start date: 2011-10-03



Possible Metopirone side effects / adverse reactions in 52 year old female

Reported by a health professional (non-physician/pharmacist) from France on 2012-03-06

Patient: 52 year old female

Reactions: Myoclonus, Diarrhoea, Hyponatraemia, Asthenia

Adverse event resulted in: hospitalization

Suspect drug(s):
Nizoral (Metopirone) (Ketoconazole)
    Dosage: oral
    Administration route: Oral
    Indication: Hyperadrenocorticism
    Start date: 2010-06-03
    End date: 2011-02-01

Metopirone
    Dosage: oral
    Administration route: Oral
    Indication: Hyperadrenocorticism
    Start date: 2011-01-06
    End date: 2011-10-21

Other drugs received by patient: Protelos 2G (Strontium Ranelate); Uvedose 100000 IU (Colecalciferol); Levothyrox (Levothyroxine); Aldactone; Tamoxifen 20 MG (Tamoxifen); Crestor; Ezetrol 10 MG (Ezetimibe)



See index of all Metopirone side effect reports >>

Drug label data at the top of this Page last updated: 2014-08-06

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