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Methotrexate (Methotrexate) - Current Clinical Trials

 
 



Methotrexate Related Clinical Trials

A Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of Methotrexate [Completed]

Assessment of Safety and Pharmacokinetics of a Low Dose of Methotrexate in Healthy Adult Male Kenyan Volunteers [Completed]

Co-Administration Of Methotrexate And CP-690,550 [Completed]

Treatment of Early RA: Minocycline in Combination With Methotrexate vs Methotrexate Alone [Completed]

The Effects of mETHotrexate Therapy on ST Segment Elevation MYocardial InfarctionS (TETHYS Trial) [Not yet recruiting]

Prevention of Methotrexate Induced Nephrotoxicity and Prolonged Drug Elimination Time With 12 Hours Prehydration [Completed]

Methotrexate and Temozolomide Versus Methotrexate, Procarbazine, Vincristine and Cytarabine [Recruiting]

Etanercept and Methotrexate in Combination or as Monotherapy in Psoriatic Arthritis [Recruiting]

VACcination In Methotrexate Treated Rheumatoid Arthritis Patients [Recruiting]

Continuous Intraventricular Methotrexate in Treating Patients With Leptomeningeal Disease [Withdrawn]

METhotrexate Therapy Effects in the Physical Capacity of Patients With ISchemic Heart Failure (METIS Trial) [Completed]

The Efficiency Of The Methotrexate At Patients Affected By Grave Pelade [Recruiting]

Methotrexate for Central Serous Chorioretinopathy Treatment Trial [Not yet recruiting]

Individualized High Dose Methotrexate to Treat Cancer in Children Who Have a Significant Risk for Side Effects to Methotrexate [Recruiting]

COMMIT (Combination Of Maintenance Methotrexate-Infliximab Trial) [Completed]

Will Glucarpidase After Methotrexate Treatment for Bone Sarcoma Lead to Fewer Side Effects and Reduce Chemotherapy Delays? [Terminated]

SC12267 (4SC-101) in Combination With Methotrexate in Patients With Rheumatoid Arthritis [Completed]

Safety and Efficacy of Intravenous ACZ885 and Oral Methotrexate Therapy in Patients With Early Rheumatoid Arthritis [Completed]

Methotrexate Infusion Into the Fourth Ventricle in Children With Malignant Fourth Ventricular Brain Tumors: A Pilot Study [Active, not recruiting]

A Safety and Efficacy Study of Ustekinumab in Patients With Plaque Psoriasis Who Have Had an Inadequate Response to Methotrexate [Completed]

An Efficacy and Safety Study of Golimumab in Patients With Active Rheumatoid Arthritis Despite Methotrexate Therapy [Completed]

A Study of the Safety and Efficacy of Golimumab in Subjects With Rheumatoid Arthritis That Are Methotrexate-naive [Completed]

A Study to Assess the Pharmacokinetics of Methotrexate Given With and Without AZD9056 in Rheumatoid Arthritis Patients [Withdrawn]

The Efficacy and Safety of Adding Methotrexate to Etanercept in Psoriasis [Completed]

A Study of the Use of Methotrexate in the Treatment of Chronic Idiopathic Urticaria [Withdrawn]

Prospective, Multicentric, Phase II Randomized Controlled Trial on Two Parallel Groups Comparing the Efficacy of Two Immunosuppressive Drugs (Methotrexate, Cyclophosphamide) in Large Granular Lymphocytes Leukemia [Recruiting]

Methotrexate Treatment for Ectopic Pregnancy [Recruiting]

Study of Etanercept Monotherapy vs Methotrexate Monotherapy for Maintenance of Rheumatoid Arthritis Remission [Recruiting]

Methotrexate in Symptomatic Knee Osteoarthritis [Completed]

Low-dose Methotrexate for Reduction GINA 5 Medications in Chronic Severe Asthma [Not yet recruiting]

Comparison of Methotrexate Versus Interferon-alfa 2b in Patients With Primary Cutaneous T-cell Lymphomas [Recruiting]

Salvage Therapy With High/Low Methotrexate for Loss of Response to Infliximab Dose Escalation [Not yet recruiting]

A Study of Tocilizumab as Monotherapy and in Combination With Methotrexate Versus Methotrexate in Patients With Early Moderate to Severe Rheumatoid Arthritis [Completed]

Mechanism of Action Study for Psoriasis [Active, not recruiting]

Two-Dose Methotrexate for Ectopic Pregnancy [Completed]

Efficacy and Safety Study of Abatacept Subcutaneous Plus Methotrexate in Inducing Remission in Adults With Very Early Rheumatoid Arthritis [Completed]

Remicade Study in Psoriatic Arthritis Patients Of Methotrexate-Na�ve Disease (RESPOND) (Study P04422) [Completed]

Low Dose Cyclosporin and Methotrexate Therapy in Diabetes [Completed]

Effect of Omega-3 Fatty Acids on Methotrexate Induced Hepatotoxicity in Children With Acute Lymphoblastic Leukemia [Completed]

Trial of Sirolimus and Methotrexate in Relapsed/Refractory Lymphoblastic Leukemia and Lymphoma [Suspended]

Utility of Intravitreal Methotrexate in Diabetic Macular Edema Resistant to Conventional Therapies [Terminated]

Inflammation Control For Elders: ICE Study [Terminated]

Methotrexate, Mannitol, Rituximab, and Carboplatin in Treating Patients With Newly Diagnosed Primary Central Nervous System Lymphoma [Recruiting]

Treatment of Non-infectious Intermediate and Posterior Uveitis Associated Macular Edema With Intravitreal Methotrexate [Terminated]

A Phase 2b/3 Study to Evaluate Efficacy and Safety of Masitinib in Comparison to Methotrexate in Patients With Active Rheumatoid Arthritis With Inadequate Response to Methotrexate or to Any Disease-Modifying Antirheumatic Drug [Recruiting]

Graft-Versus-Host Disease (GVHD) Prophylaxis After Allogeneic Peripheral Blood Hematopoietic Cell Transplantation [Completed]

Vorinostat, Tacrolimus, and Methotrexate in Preventing GVHD After Stem Cell Transplant in Patients With Hematological Malignancies [Completed]

Open-label Leucovorin Pharmacokinetic Study in Patients Receiving High Dose Methotrexate With or Without Voraxaze [Completed]

Efficacy Study of Methotrexate to Treat Sarcoid-associated Uveitis [Terminated]

Tac, Mini-MTX, MMF Versus Tac, MTX for GVHD Prevention [Recruiting]

An Effectiveness and Safety Study of Intravenous Golimumab in Patients With Active Rheumatoid Arthritis Despite Treatment With Methotrexate Therapy [Completed]

Effects of Tranilast on Pharmacokinetics of Methotrexate (MTX) in Patients With Rheumatoid Arthritis (RA) [Withdrawn]

Methotrexate in the Treatment of Chronic Idiopathic Urticaria [Recruiting]

Dose Dense Adjuvant CMF (Cyclophosphamide, Methotrexate, Fluorouracil) at 14 and 10-11 Day Intervals for Women With Early Stage Breast Cancer [Completed]

Dose Response and Safety Study of Topical Methotrexate for the Treatment of Fingernail Psoriasis [Active, not recruiting]

The Effects of Infliximab Versus Methotrexate in the Treatment of Moderate to Severe Psoriasis (Study P04271AM2)(COMPLETED) [Completed]

Methotrexate, Vincristine, Pegylated L-Asparaginase and Dexamethasone (MOAD) in Acute Lymphoblastic Leukemia (ALL) Salvage [Completed]

Methotrexate Polyglutamates as a Marker of Clinical Response and Toxicity in the Treatment of Psoriasis [Enrolling by invitation]

Doxorubicin With Cisplatin, High-Dose Methotrexate, and Additional Risk-Adapted Outpatient Chemotherapy [Terminated]

A Study of Effectiveness and Safety of CNTO 136 in Patients With Active Rheumatoid Arthritis Despite Methotrexate Therapy [Completed]

Concomitant Longitudinal Evaluation of Adalimumab With Methotrexate in the Real World: the CLEAR Study [Recruiting]

Aggressive Combination Drug Therapy in Very Early Polyarticular Juvenile Idiopathic Arthritis [Active, not recruiting]

Initial Treatment With Golimumab in Early PsA [Recruiting]

Sirolimus, Tacrolimus and Short Course Methotrexate for Prevention of Acute GVHD in Recipients of Mismatched Unrelated Donor Allogeneic Stem Cell Transplantation [Active, not recruiting]

A Phase III Study of Abatacept in Patients With Rheumatoid Arthritis and an Inadequate Response to Methotrexate [Completed]

A Study to Determine the Effect of Methotrexate (MTX) Dose on Clinical Outcome and Ultrasonographic Signs in Subjects With Moderately to Severely Active Rheumatoid Arthritis (RA) Treated With Adalimumab (MUSICA) [Completed]

Study of LX3305 and Methotrexate in Subjects With Stable Rheumatoid Arthritis [Completed]

Erosive Osteoarthritis of the Hands: Treatment by Methotrexate Versus Placebo [Recruiting]

A Multi-center, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Certolizumab Pegol in Combination With Methotrexate in the Treatment of Disease Modifying Antirheumatic Drugs (DMARD)-na�ve Adults With Early Active Rheumatoid Arthritis [Active, not recruiting]

A Study of RoActemra/Actemra (Tocilizumab) With or Without Methotrexate in Patients With Mild to Moderate Rheumatoid Arthritis With an Inadequate Response to Methotrexate [Completed]

Liposomal Cytarabine and High-Dose Methotrexate in Treating Patients With Central Nervous System Metastases From Breast Cancer [Completed]

CAMEO: Canadian Methotrexate and Etanercept Outcome Study [Completed]

Leflunomide Versus Sulfasalazine/Methotrexate in Rheumatoid Arthritis:an Ultrasound/Magnetic Resonance Imaging Study [Terminated]

Study to Assess the Short- and Long-term Efficacy of Certolizumab Pegol Plus Methotrexate Compared to Adalimumab Plus Methotrexate in Subjects With Moderate to Severe Rheumatoid Arthritis (RA) Inadequately Responding to Methotrexate [Active, not recruiting]

Combined Treatment of Methotrexate + Glucocorticoids Versus Glucocorticoids Alone in Patients With Polymyositis and Dermatomyositis [Active, not recruiting]

Vinblastine and Methotrexate in Children With Pulmonary Vein Stenosis [Completed]

A Canadian Study to Evaluate Early Use of Adalimumab After Methotrexate Failure in Early Rheumatoid Arthritis [Completed]

Sirolimus/Tacrolimus Versus Tacrolimus/Methotrexate for Preventing Graft-Versus-Host Disease (GVHD) (BMT CTN 0402) [Active, not recruiting]

Topical Steroids Alone or Associated With Methotrexate in Bullous Pemphigoid [Recruiting]

Comparison Between Cyclophosphamide and Combination of Methotrexate + Calcineurin Inhibitor for GVHD Prophylaxis [Recruiting]

Effect of the Combination of Methotrexate and Adalimumab on Reduction of Immunization in Ankylosing Spondylitis (COMARIS) [Active, not recruiting]

Tacrolimus and Mycophenolate Mofetil (MMF) in GVHD Prophylactic Regimen Compared to Tacrolimus and Methotrexate (MTX [Completed]

A Study on the Impact of Methotrexate Discontinuation on the Efficacy of Subcutaneous RoActemra/Actemra (Tocilizumab) With Methotrexate in Patients With Moderate to Severe Active Rheumatoid Arthritis [Recruiting]

Study of Two Different Starting Doses of Methotrexate When Starting Treatment in Rheumatoid Arthritis [Completed]

A Drug Interaction Study to Evaluate the Pharmacokinetics of ASP015K and Methotrexate in Patients With Rheumatoid Arthritis [Completed]

Methotrexate (Rheumatrex) High Dose Special Investigation (Regulatory Post Marketing Commitment Plan) [Recruiting]

Tacrolimus, Sirolimus and Methotrexate as Graft Versus Host Disease Prophylaxis After Blood Stem Cell Transplantation [Completed]

Bortezomib Plus Tacrolimus and Methotrexate to Prevent Graft Versus Host Disease (GVHD) After Mismatched Allogeneic Non-Myeloablative Blood Stem Cell Transplantation [Completed]

A Phase 3 Trial of Brentuximab Vedotin(SGN-35) Versus Physician's Choice (Methotrexate or Bexarotene) in Patients With CD30-Positive Cutaneous T-Cell Lymphoma [Recruiting]

Methotrexate or Pentostatin for Graft-versus-host Disease Prophylaxis in Risk-adapted Allogeneic Bone Marrow Transplantation for Hematologic Malignancies [Completed]

Ofatumumab in Combination With Cyclophosphamide, Doxorubicin Hydrochloride, Vincristine Sulfate, and Dexamethasone Alternating With Ofatumumab in Combination With Cytarabine and Methotrexate in Treating Patients With Newly Diagnosed Mantle Cell Lymphoma [Recruiting]

Phase III Study of Vinflunine Plus Methotrexate Versus Methotrexate Alone in Patients With Head and Neck Cancer [Recruiting]

Sequential Administration of Oral 6-Thioguanine (6-TG) After Methotrexate (MTX) in Patients With Relapsed Hodgkin's Disease (Phase II) [Completed]

A Pilot Study of Dextromethorphan for the Prevention and Treatment of Methotrexate Neurotoxicity [Terminated]

Study of Methotrexate Efficacy Versus Cyclosporine in Moderate to Severe Atopic Dermatitis Patients [Completed]

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