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Methotrexate (Methotrexate) - Current Clinical Trials

 


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Methotrexate Related Clinical Trials

Treatment of Early RA: Minocycline in Combination With Methotrexate vs Methotrexate Alone [Completed]

Abatacept and Infliximab in Combination With Methotrexate in Subjects With Rheumatoid Arthritis [Completed]

Study Comparing Etanercept and Methotrexate vs. Methotrexate Alone in Rheumatoid Arthritis [Active, not recruiting]

A Study of the Safety and Efficacy of Golimumab in Subjects With Rheumatoid Arthritis That Are Methotrexate-Naive [Active, not recruiting]

Remicade Study in Psoriatic Arthritis Patients Of Methotrexate-Naïve Disease (RESPOND) (Study P04422AM1)(COMPLETED) [Completed]

Study Comparing Enbrel (Etanercept) Plus Methotrexate Versus Enbrel Alone in Active Rheumatoid Arthritis Despite Current Methotrexate Therapy [Completed]

Two-Dose Methotrexate for Ectopic Pregnancy [Completed]

Evaluate Whether Combination Therapy With Methotrexate and Raptiva in Psoriasis Patients is Safe and Increases Efficacy [Active, not recruiting]

Study to Assess Efficacy of Tacrolimus + Methotrexate Vs. Placebo + Methotrexate in Treatment of Rheumatoid Arthritis [Completed]

A Study of the Safety and Efficacy of Intravenous CNTO 148 (Golimumab) in Patients With Active Rheumatoid Arthritis Despite Methotrexate Therapy [Active, not recruiting]

A Study of the Safety and Efficacy of Golimumab in Subjects With Active Rheumatoid Arthritis Despite Methotrexate Therapy [Active, not recruiting]

Remission in Early Rheumatoid Arthritis [Active, not recruiting]

Head and Neck Phase III Iressa Versus Methotrexate Refractory: Iressa Versus Methotrexate (IMEX) [Completed]

Adalimumab in Combination With Methotrexate vs Methotrexate Alone in Early Rheumatoid Arthritis [Completed]

The Effects of Infliximab Versus Methotrexate in the Treatment of Moderate to Severe Psoriasis (Study P04271AM2) [Active, not recruiting]

COMMIT (Combination Of Maintenance Methotrexate-Infliximab Trial) [Active, not recruiting]

Methotrexate Alone Versus Combination of Methotrexate and Subcutaneous Fludarabine for Severe Rheumatoid Arthritis: Safety, Tolerance and Efficacy [Completed]

High-Dose Methotrexate in Treating Young Patients With Solid Tumors [Suspended]

Study Evaluating the Combination of Etanercept and Methotrexate in Rheumatoid Arthritis Subjects [Completed]

The Influence of Methotrexate on the Metabolism and Vascular Effects of Adenosine in Humans [Completed]

Study Comparing Etanercept Plus Methotrexate to Either Etanercept or Methotrexate Alone in Rheumatoid Arthritis. [Completed]

Comparison of High-Dose Methotrexate (HDM) Plus Doxorubicin to HDM Plus Etoposide-Ifosfamide in Osteosarcoma Children [Completed]

Tacrolimus, Sirolimus and Methotrexate as Graft Versus Host Disease Prophylaxis After Blood Stem Cell Transplantation [Completed]

Sequential Administration of Oral 6-Thioguanine (6-TG) After Methotrexate (MTX) in Patients With Relapsed Hodgkin's Disease (Phase II) [Active, not recruiting]

Study of Methotrexate in Lupus Erythematosus [Completed]

Methotrexate in Ankylosing Spondylitis (MTX in AS) [Active, not recruiting]

Efficacy and Safety of CDP870 and Methotrexate Compared to Methotrexate Alone in Subjects With Rheumatoid Arthritis

A Study of Imatinib 400 Mg Once Daily in Combination With Methotrexate in the Treatment of Rheumatoid Arthritis. [Completed]

Methotrexate and Glucocorticoids in Treating Patients With Newly Diagnosed Acute Graft-Versus-Host Disease After Donor Stem Cell Transplant

Pharmacologic Study of Methotrexate in Patients Undergoing Stereotactic Biopsy for Recurrent High-Grade Glioma [Completed]

A Phase I Study of Methotrexate for HIV Infection [Completed]

A Study to Evaluate Rituximab in Combination With Methotrexate in Methotrexate-Naive Patients With Active Rheumatoid Arthritis (IMAGE)

WEGENT - Comparison of Methotrexate or Azathioprine as Maintenance Therapy for ANCA-Associated Vasculitides [Active, not recruiting]

A Drug Interaction Study Between Tocilizumab, Methotrexate and Simvastatin on Patients With Rheumatoid Arthritis. [Active, not recruiting]

Phase I/II Study of Pentostatin Combined With Tacrolimus and Mini-Methotrexate for GVHD Prevention After MUD BMT [Active, not recruiting]

Rapamycin Vs Methotrexate in Diffuse SSc [Active, not recruiting]

A Study to Assess the Effect of Tocilizumab + Methotrexate on Signs and Symptoms in Patients With Moderate to Severe Active Rheumatoid Arthritis Currently on Methotrexate Therapy [Completed]

SB-681323-Methotrexate Interaction Study [Completed]

A Phase IIIb Study of BMS-188667 in Subjects With Active Rheumatoid Arthritis and Inadequate Response to Methotrexate [Recruiting]

Methotrexate, Procarbazine, Lomustine, Dexamethasone, and Cytarabine in Treating Patients With Primary CNS Lymphoma [Active, not recruiting]

A Comparison of Methotrexate Alone or Combined to Infliximab or to Pulse Methylprednisolone in Early Rheumatoid Arthritis: A Magnetic Resonance Imaging Study [Completed]

Comparing Methotrexate Followed by Misoprostol to Misoprostol Alone for Early Abortion [Completed]

Study Evaluating Etanercept and Methotrexate in Plaque Psoriasis [Active, not recruiting]

Study Of The Safety Of CE 224,545 And Methotrexate In Patients With Rheumatoid Arthritis [Recruiting]

Combination Therapy With Avonex and BiMonthly High Dose Intravenous Methotrexate in Multiple Sclerosis [Active, not recruiting]

Steroids and Methotrexate to Treat Systemic Vasculitis [Completed]

Mannitol Followed By Methotrexate and Carboplatin With or Without Trastuzumab in Treating Women With Breast Cancer That Has Spread to the Brain [Active, not recruiting]

High-Dose Methotrexate and Leucovorin in Treating Patients With Newly Diagnosed Glioblastoma Multiforme [No longer recruiting]

Methotrexate, Cyclophosphamide, and Etoposide Phosphate Given With Osmotic Blood-Brain Barrier Disruption Plus Dexamethasone and Cytarabine in Treating Patients With Primary CNS Lymphoma

Methotrexate Plus Dipyridamole in Treating Patients With Advanced Ovarian Cancer [Active, not recruiting]

Methotrexate Compared With Dactinomycin in Treating Patients With Gestational Trophoblastic Neoplasia [Active, not recruiting]

Methotrexate, Trimetrexate Glucuronate, and Leucovorin in Treating Patients With Refractory or Recurrent Osteosarcoma [Completed]

Methotrexate Compared With Paclitaxel in Treating Patients With Advanced Head and Neck Cancer [No longer recruiting]

Methotrexate and Thiotepa in Treating Patients With Newly Diagnosed Primary CNS Lymphoma [Completed]

Methotrexate With or Without Antineoplaston Therapy in Treating Postmenopausal Women With Advanced Refractory Breast Cancer [Withdrawn]

Fludarabine and Busulfan Followed by Donor Peripheral Stem Cell Transplant and Antithymocyte Globulin, Tacrolimus, and Methotrexate in Treating Patients With Myeloid Cancer [Active, not recruiting]

Sirolimus, Tacrolimus, and Methotrexate in Preventing Acute Graft-Versus-Host Disease in Patients With Hematologic Cancer Who Are Undergoing Donor Stem Cell Transplantation [No longer recruiting]

Adalimumab Administered in Korean Rheumatoid Arthritis Subjects Treated With Methotrexate [Completed]

Methotrexate and Cyclosporine in Treatment of Early Rheumatoid Arthritis [Completed]

Prevention of Methotrexate Induced Nephrotoxicity and Prolonged Drug Elimination Time With 12 Hours Prehydration [Recruiting]

A Phase III Study of Abatacept in Patients With Rheumatoid Arthritis, With an Inadequate Response to Methotrexate [Recruiting]

Low-Dose Oral Methotrexate Versus Colchicine for Primary Biliary Cirrhosis [Completed]

Vinblastine and Methotrexate in Treating Children With Desmoid Tumors [Completed]

A Pharmacokinetic Study to Determine the Oral Bioavailability of Methotrexate in Patients With Inflammatory Bowel Disease [Completed]

Methotrexate and Temozolomide Versus Methotrexate, Procarbazine, Vincristine and Cytarabine [Recruiting]

Multiple Ascending Dose Study of BMS-582949 in Patients With Stable Rheumatoid Arthritis on the Methotrexate Background [Recruiting]

Dose Response and Safety Study of Topical Methotrexate for the Treatment of Fingernail Psoriasis [Recruiting]

The Effects of Infliximab in Korean Patients With Active Rheumatoid Arthritis Despite Methotrexate Treatment (Study P04280)(COMPLETED) [Completed]

Study Evaluating ERB-041 With Methotrexate in Rheumatoid Arthritis [No longer recruiting]

A Study of Ocrelizumab in Combination With Methotrexate in Patients With Rheumatoid Arthritis Who Are Naive to Methotrexate (FILM) [Recruiting]

Dose Dense Adjuvant CMF (Cyclophosphamide, Methotrexate, Fluorouracil) at 14 and 10-11 Day Intervals for Women With Early Stage Breast Cancer [Recruiting]

A Study to Evaluate Rituximab in Combination With Methotrexate Compared to Methotrexate Alone in Patients With Rheumatoid Arthritis

Open-Label Leucovorin Pharmacokinetic Study in Patients Receiving High Dose Methotrexate With or Without Voraxaze [Recruiting]

Methotrexate, Glucarpidase, and Leucovorin in Treating Patients With Newly Diagnosed Primary Central Nervous System Lymphoma [Recruiting]

Combined Treatment of Methotrexate + Glucocorticoids Versus Glucocorticoids Alone in Patients With Polymyositis and Dermatomyositis [Recruiting]

Sirolimus, Tacrolimus and Short Course Methotrexate for Prevention of Acute GVHD in Recipients of Mismatched Unrelated Donor Allogeneic Stem Cell Transplantation [Recruiting]

Multicenter Randomized Prospective Trial Comparing Methotrexate Alone or in Combination With Adalimumab in Early Arthritis [Recruiting]

Ursodiol-Methotrexate for Primary Biliary Cirrhosis [Completed]

Study Evaluating Efficacy / Safety of Etanercept + Methotrexate Compared to Usual Treatment in Moderate Rheumatoid Arthritis (RA) Subjects [Not yet recruiting]

A Study of the Use of Methotrexate in the Treatment of Chronic Idiopathic Urticaria [Recruiting]

A Pilot Study of Dextromethorphan for the Prevention and Treatment of Methotrexate Neurotoxicity [Recruiting]

Rheumatoid Arthritis: Comparison of Active Therapies in Patients With Active Disease Despite Methotrexate Therapy [Recruiting]

The Infliximab Rheumatoid Arthritis Methotrexate Tapering (iRAMT) Protocol [Completed]

Vinblastine and Methotrexate in Children With Pulmonary Vein Stenosis [Recruiting]

Methotrexate Polyglutamate Levels as a Marker for the Clinical Outcome in the Treatment of Rheumatoid Arthritis [Recruiting]

Randomized Study Comparing CMF and Goserelin + Tamoxifen in Premenopausal Receptor-Positive Patients [Completed]

Infliximab Plus Methotrexate for the Treatment of Rheumatoid Arthritis [Completed]

AVONEX® Combination Trial - "ACT" [Completed]

Study of Glucarpidase (CPG2) for the Management of Patients With Delayed Methotrexate Clearance [Completed]

High-Dose Methotrexate in Treating Young Patients With Residual Ependymoma [Recruiting]

A Study of Retreatment With MabThera (Rituximab) in Combination With Methotrexate in Patients With Rheumatoid Arthritis (RA) [No longer recruiting]

A Study of Safety and Efficacy Comparing ABT-874 Versus Methotrexate in Subjects With Moderate to Severe Plaque Psoriasis [Not yet recruiting]

Comparison Of 6 CP-690,550 Doses Vs.Placebo, Each Combined With Methotrexate, For The Treatment Of Rheumatoid Arthritis [Recruiting]

Methotrexate in the Treatment of Axial Spondyloarthritis [Recruiting]

Bortezomib Plus Tacrolimus and Methotrexate to Prevent GVHD After Mismatched Allogeneic Non-Myeloablative Blood Stem Cell Transplantation [Recruiting]

Safety and Tolerability of Rituxan With Methotrexate and Etanercept or Methotrexate and Adalimumab in Patients With Active Rheumatoid Arthritis [Recruiting]

Comparison of Methotrexate vs Placebo in Steroid-Refractory Ulcerative Colitis [Recruiting]

Effects of Tranilast on pk of MTX in Patients With RA [Not yet recruiting]

Metronomic Low-Dose Cyclophosphamide and Methotrexate With or Without Bevacizumab in Treating Women With Metastatic Breast Cancer [No longer recruiting]

Cyclophosphamide and Prednisone Followed by Methotrexate To Treat Vasculitides [Completed]

Methotrexate, Vinblastine, Doxorubicin and Cisplatin (MVAC) Followed by Gemcitabine Plus Cisplatin (GEM+CDDP) in Locally Advanced or Metastatic Bladder Cancer [Recruiting]

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