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Methotrexate (Methotrexate) - Current Clinical Trials

 
 



Methotrexate Related Clinical Trials

Treatment of Early RA: Minocycline in Combination With Methotrexate vs Methotrexate Alone [Completed]

Abatacept and Infliximab in Combination With Methotrexate in Subjects With Rheumatoid Arthritis [Completed]

Study Comparing Etanercept and Methotrexate vs. Methotrexate Alone in Rheumatoid Arthritis [Active, not recruiting]

A Study of the Safety and Efficacy of Golimumab in Subjects With Rheumatoid Arthritis That Are Methotrexate-Naive [Active, not recruiting]

Remicade Study in Psoriatic Arthritis Patients Of Methotrexate-Naïve Disease (RESPOND) (Study P04422AM1)(COMPLETED) [Completed]

Study Comparing Enbrel (Etanercept) Plus Methotrexate Versus Enbrel Alone in Active Rheumatoid Arthritis Despite Current Methotrexate Therapy [Completed]

Two-Dose Methotrexate for Ectopic Pregnancy [Completed]

Evaluate Whether Combination Therapy With Methotrexate and Raptiva in Psoriasis Patients is Safe and Increases Efficacy [Active, not recruiting]

Study to Assess Efficacy of Tacrolimus + Methotrexate Vs. Placebo + Methotrexate in Treatment of Rheumatoid Arthritis [Completed]

A Study of the Safety and Efficacy of Intravenous CNTO 148 (Golimumab) in Patients With Active Rheumatoid Arthritis Despite Methotrexate Therapy [Active, not recruiting]

A Study of the Safety and Efficacy of Golimumab in Subjects With Active Rheumatoid Arthritis Despite Methotrexate Therapy [Active, not recruiting]

SC12267 (4SC-101) in Combination With Methotrexate in Patients With Rheumatoid Arthritis [Recruiting]

Remission in Early Rheumatoid Arthritis [Active, not recruiting]

Continuous Intraventricular Methotrexate in Treating Patients With Leptomeningeal Disease [Not yet recruiting]

Head and Neck Phase III Iressa Versus Methotrexate Refractory: Iressa Versus Methotrexate (IMEX) [Completed]

Assessment of Safety and Pharmacokinetics of a Low Dose of Methotrexate in Healthy Adult Male Kenyan Volunteers [Not yet recruiting]

TRANSIT - A Safety and Efficacy Study of Ustekinumab in Patients With Plaque Psoriasis Who Have Had an Inadequate Response to Methotrexate [Recruiting]

Adalimumab in Combination With Methotrexate vs Methotrexate Alone in Early Rheumatoid Arthritis [Completed]

Methotrexate and Temozolomide Versus Methotrexate, Procarbazine, Vincristine and Cytarabine [Recruiting]

A Phase III Study to Evaluate the Efficacy and Safety of ENIA11 in Combination With Methotrexate Versus Methotrexate Alone in Patients With RA [Recruiting]

Phase IIB Rheumatoid Arthritis Dose Ranging Study for BMS-945429 in Subjects Who Are Not Responding to Methotrexate [Recruiting]

A Phase 2b/3 Study to Evaluate Efficacy and Safety of Masitinib in Comparison to Methotrexate in Patients With Active Rheumatoid Arthritis With Inadequate Response to Methotrexate or to Any Disease-Modifying Antirheumatic Drug [Recruiting]

Study to Assess the Short- and Long-term Efficacy of Certolizumab Pegol Plus Methotrexate Compared to Adalimumab Plus Methotrexate in Subjects With Moderate to Severe Rheumatoid Arthritis (RA) Inadequately Responding to Methotrexate [Recruiting]

A Pilot Study: Methotrexate Infusion in Children With Brain Tumors [Recruiting]

Methotrexate for Central Serous Chorioretinopathy Treatment Trial [Not yet recruiting]

The Effects of Infliximab Versus Methotrexate in the Treatment of Moderate to Severe Psoriasis (Study P04271AM2) [Active, not recruiting]

A Study of Tocilizumab as Monotherapy and in Combination With Methotrexate Versus Methotrexate in Patients With Early Moderate to Severe Rheumatoid Arthritis [Recruiting]

Mechanism of Action Study for Psoriasis [Recruiting]

A Study of RoActemra/Actemra (Tocilizumab) With or Without Methotrexate in Patients With Mild to Moderate Rheumatoid Arthritis With an Inadequate Response to Methotrexate [Recruiting]

Study to Determine the Effects of Different Doses of Methotrexate (MTX) When Taken With Adalimumab in Subjects With Early Rheumatoid Arthritis (RA) [Recruiting]

COMMIT (Combination Of Maintenance Methotrexate-Infliximab Trial) [Active, not recruiting]

Trial of Sirolimus and Methotrexate in Relapsed/Refractory Lymphoblastic Leukemia and Lymphoma [Recruiting]

A Multicenter, Randomized, Double-blind, Pladebo-controlled Study of the Combination Therapy of T-614 and Methotrexate in Rheumatoid Arthritis Patients With an Inadequate Response to Methotrexate [Recruiting]

Leflunomide Versus Sulfasalazine/Methotrexate in Rheumatoid Arthritis:an Ultrasound/Magnetic Resonance Imaging Study [Recruiting]

High-dose Methotrexate and Liposomal Cytarabine in Treating Patients With CNS Metastases From Breast Cancer [Recruiting]

A Canadian Study to Evaluate Early Use of Adalimumab After Methotrexate Failure in Early Rheumatoid Arthritis [Recruiting]

Methotrexate Alone Versus Combination of Methotrexate and Subcutaneous Fludarabine for Severe Rheumatoid Arthritis: Safety, Tolerance and Efficacy [Completed]

High-Dose Methotrexate in Treating Young Patients With Solid Tumors [Suspended]

Efficacy and Safety of Abatacept Subcutaneous (SC) in Combination With Methotrexate in Adults With Very Early Rheumatoid Arthritis (RA) [Recruiting]

Study Evaluating the Combination of Etanercept and Methotrexate in Rheumatoid Arthritis Subjects [Completed]

Erosive Osteoarthritis of the Hands: Treatment by Methotrexate Versus Placebo [Recruiting]

Tacrolimus/Sirolimus/Methotrexate Versus Tacrolimus/Methotrexate or Cyclosporine/Mycophenolate Mofetil for GVHD Prophylaxis After Reduced Intensity Allogeneic Stem Cell Transplantation for Patients With Lymphoma [Recruiting]

Methotrexate (Rheumatrex) High Dose Special Investigation (Regulatory Post Marketing Commitment Plan) [Recruiting]

Multicenter Randomized Prospective Trial Comparing Methotrexate Alone or in Combination With Adalimumab in Early Arthritis [Recruiting]

Methotrexate, Glucarpidase, and Leucovorin in Treating Patients With Newly Diagnosed Primary Central Nervous System Lymphoma [Recruiting]

Sirolimus, Tacrolimus and Short Course Methotrexate for Prevention of Acute GVHD in Recipients of Mismatched Unrelated Donor Allogeneic Stem Cell Transplantation [Recruiting]

Study of Two Different Starting Doses of Methotrexate When Starting Treatment in Rheumatoid Arthritis [Recruiting]

Rituximab&Methotrexate Chemotherapy w/BBBD & Sodium Thiosulfate Chemoprotection for Patients With Newly Diagnosed PCNSL [Recruiting]

Comparative Study of the Clinical Response and Cardiorespiratory Endurance in Early Rheumatoid Arthritis Patients Treated With Tocilizumab or Methotrexate [Recruiting]

Combined Treatment of Methotrexate + Glucocorticoids Versus Glucocorticoids Alone in Patients With Polymyositis and Dermatomyositis [Recruiting]

A Study of the Use of Methotrexate in the Treatment of Chronic Idiopathic Urticaria [Recruiting]

Doxorubicin With Cisplatin, High-Dose Methotrexate, and Additional Risk-Adapted Outpatient Chemotherapy [Recruiting]

Methotrexate, Vincristine, Pegylated L-Asparaginase and Dexamethasone (MOAD) in Acute Lymphoblastic Leukemia (ALL) Salvage [Recruiting]

Efficacy Study of Methotrexate to Treat Sarcoid-associated Uveitis [Recruiting]

Ofatumumab in Combination With Cyclophosphamide, Doxorubicin Hydrochloride, Vincristine Sulfate, and Dexamethasone Alternating With Ofatumumab in Combination With Cytarabine and Methotrexate in Treating Patients With Newly Diagnosed Mantle Cell Lymphoma [Recruiting]

Outpatient Administration of High Dose Methotrexate (HD MTX) in Patients With Osteosarcoma [Not yet recruiting]

The Influence of Methotrexate on the Metabolism and Vascular Effects of Adenosine in Humans [Completed]

Study Comparing Etanercept Plus Methotrexate to Either Etanercept or Methotrexate Alone in Rheumatoid Arthritis. [Completed]

Comparison of High-Dose Methotrexate (HDM) Plus Doxorubicin to HDM Plus Etoposide-Ifosfamide in Osteosarcoma Children [Completed]

Tacrolimus, Sirolimus and Methotrexate as Graft Versus Host Disease Prophylaxis After Blood Stem Cell Transplantation [Completed]

Methotrexate or Pentostatin for Graft-versus-host Disease Prophylaxis in Risk-adapted Allogeneic Bone Marrow Transplantation for Hematologic Malignancies [Recruiting]

Sequential Administration of Oral 6-Thioguanine (6-TG) After Methotrexate (MTX) in Patients With Relapsed Hodgkin's Disease (Phase II) [Active, not recruiting]

Study of Methotrexate in Lupus Erythematosus [Completed]

Methotrexate in Ankylosing Spondylitis (MTX in AS) [Active, not recruiting]

Efficacy and Safety of CDP870 and Methotrexate Compared to Methotrexate Alone in Subjects With Rheumatoid Arthritis

A Study of Imatinib 400 Mg Once Daily in Combination With Methotrexate in the Treatment of Rheumatoid Arthritis. [Completed]

Methotrexate and Glucocorticoids in Treating Patients With Newly Diagnosed Acute Graft-Versus-Host Disease After Donor Stem Cell Transplant

Pharmacologic Study of Methotrexate in Patients Undergoing Stereotactic Biopsy for Recurrent High-Grade Glioma [Completed]

A Phase I Study of Methotrexate for HIV Infection [Completed]

A Study to Evaluate Rituximab in Combination With Methotrexate in Methotrexate-Naive Patients With Active Rheumatoid Arthritis (IMAGE)

WEGENT - Comparison of Methotrexate or Azathioprine as Maintenance Therapy for ANCA-Associated Vasculitides [Active, not recruiting]

A Drug Interaction Study Between Tocilizumab, Methotrexate and Simvastatin on Patients With Rheumatoid Arthritis. [Active, not recruiting]

Phase I/II Study of Pentostatin Combined With Tacrolimus and Mini-Methotrexate for GVHD Prevention After MUD BMT [Active, not recruiting]

Rapamycin Vs Methotrexate in Diffuse SSc [Active, not recruiting]

A Study to Assess the Effect of Tocilizumab + Methotrexate on Signs and Symptoms in Patients With Moderate to Severe Active Rheumatoid Arthritis Currently on Methotrexate Therapy [Completed]

SB-681323-Methotrexate Interaction Study [Completed]

A Phase IIIb Study of BMS-188667 in Subjects With Active Rheumatoid Arthritis and Inadequate Response to Methotrexate [Recruiting]

Methotrexate, Procarbazine, Lomustine, Dexamethasone, and Cytarabine in Treating Patients With Primary CNS Lymphoma [Active, not recruiting]

A Comparison of Methotrexate Alone or Combined to Infliximab or to Pulse Methylprednisolone in Early Rheumatoid Arthritis: A Magnetic Resonance Imaging Study [Completed]

Comparing Methotrexate Followed by Misoprostol to Misoprostol Alone for Early Abortion [Completed]

Study Evaluating Etanercept and Methotrexate in Plaque Psoriasis [Active, not recruiting]

Study Of The Safety Of CE 224,545 And Methotrexate In Patients With Rheumatoid Arthritis [Recruiting]

Combination Therapy With Avonex and BiMonthly High Dose Intravenous Methotrexate in Multiple Sclerosis [Active, not recruiting]

Steroids and Methotrexate to Treat Systemic Vasculitis [Completed]

Mannitol Followed By Methotrexate and Carboplatin With or Without Trastuzumab in Treating Women With Breast Cancer That Has Spread to the Brain [Not yet recruiting]

High-Dose Methotrexate and Leucovorin in Treating Patients With Newly Diagnosed Glioblastoma Multiforme [No longer recruiting]

Methotrexate, Cyclophosphamide, and Etoposide Phosphate Given With Osmotic Blood-Brain Barrier Disruption Plus Dexamethasone and Cytarabine in Treating Patients With Primary CNS Lymphoma

Methotrexate Plus Dipyridamole in Treating Patients With Advanced Ovarian Cancer [Active, not recruiting]

Methotrexate Compared With Dactinomycin in Treating Patients With Gestational Trophoblastic Neoplasia [Active, not recruiting]

Methotrexate, Trimetrexate Glucuronate, and Leucovorin in Treating Patients With Refractory or Recurrent Osteosarcoma [Completed]

Methotrexate Compared With Paclitaxel in Treating Patients With Advanced Head and Neck Cancer [No longer recruiting]

Methotrexate and Thiotepa in Treating Patients With Newly Diagnosed Primary CNS Lymphoma [Completed]

Methotrexate With or Without Antineoplaston Therapy in Treating Postmenopausal Women With Advanced Refractory Breast Cancer [Withdrawn]

Fludarabine and Busulfan Followed by Donor Peripheral Stem Cell Transplant and Antithymocyte Globulin, Tacrolimus, and Methotrexate in Treating Patients With Myeloid Cancer [Active, not recruiting]

Sirolimus, Tacrolimus, and Methotrexate in Preventing Acute Graft-Versus-Host Disease in Patients With Hematologic Cancer Who Are Undergoing Donor Stem Cell Transplantation [No longer recruiting]

Adalimumab Administered in Korean Rheumatoid Arthritis Subjects Treated With Methotrexate [Completed]

Methotrexate and Cyclosporine in Treatment of Early Rheumatoid Arthritis [Completed]

A Phase III Study of Abatacept in Patients With Rheumatoid Arthritis, With an Inadequate Response to Methotrexate [Recruiting]

Prevention of Methotrexate Induced Nephrotoxicity and Prolonged Drug Elimination Time With 12 Hours Prehydration [Recruiting]

Low-Dose Oral Methotrexate Versus Colchicine for Primary Biliary Cirrhosis [Completed]

Vinblastine and Methotrexate in Treating Children With Desmoid Tumors [Completed]

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