Methocarbamol (Methocarbamol) - Summary

METHOCARBAMOL SUMMARY

Methocarbamol Tablets, USP 500 mg
Methocarbamol Tablets, USP 750 mg

Methocarbamol is an aromatic glycerol ether and is a close chemical relative to mephenesin carbamate, the oldest and most extensively studied of the drugs in this class.

Methocarbamol Tablets are indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomforts associated with acute, painful musculoskeletal conditions. The mode of action of this drug has not been clearly identified, but may be related to its sedative properties. Methocarbamol does not directly relax tense skeletal muscles in man.

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NEWS HIGHLIGHTS

Published Studies Related to Methocarbamol

Bioequivalence study with two different oral formulations of methocarbamol in healthy subjects. A mono-centre, comparative, randomized, open-label, single-dose, 2-way crossover study. [2009]
CONCLUSION: In this study bioequivalence could be demonstrated with respect to rate and extent of methocarbamol exposure.

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Clinical Trials Related to Methocarbamol

A Pilot Study of Recombinant Human Relaxin (rhRlx) in Compensated Congestive Heart Failure [Completed]
This trial is a single center, open-label, dose-finding study of recombinant human relaxin (rhRlx) given intravenously (IV) to patients with stable, compensated CHF.

Recombinant Human Relaxin for the Treatment of Decompensated CHF [Active, not recruiting]
Two doses of relaxin will be compared to placebo for the treatment of patients with decompensated CHF

Efficacy and Safety of Relaxin for the Treatment of Acute Heart Failure [Recruiting]
Different doses of relaxin will be compared to placebo to determine efficacy and safety for the treatment of patients hospitalized with acute heart failure

Evaluation of the Safety of Relaxin in Preeclampsia [Recruiting]
The purpose of this study is to determine whether different doses of recombinant human relaxin is safe when given to women with severe preeclampsia

Recombinant Human Relaxin (rhRlx) in Pregnant Women Scheduled for Induction of Labor [Completed]
The purpose of this study is to assess the safety and efficacy of rhRlx for cervical ripening, when compared to a placebo.

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