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Methenamine Hippurate (Methenamine Hippurate) - Summary

 
 



SUMMARY

METHENAMINE HIPPURATE TABLETS USP
1 g

Rx only

Methenamine hippurate is an antibacterial agent. To reduce the development of drug-resistant bacteria and maintain the effectiveness of methenamine hippurate tablets USP and other antibacterial drugs, methenamine hippurate tablets USP should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.

Methenamine hippurate tablets USP are indicated for prophylactic or suppressive treatment of frequently recurring urinary tract infections when long-term therapy is considered necessary. This drug should only be used after eradication of the infection by other appropriate antimicrobial agents.

To reduce the development of drug-resistant bacteria and maintain the effectiveness of methenamine hippurate tablets USP and other antibacterial drugs, methenamine hippurate tablets USP should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.


See all Methenamine Hippurate indications & dosage >>

NEWS HIGHLIGHTS

Media Articles Related to Methenamine Hippurate (Methenamine)

Could Adaptable Bacteria Cause Repeat Urinary Tract Infections?
Source: MedicineNet E. Coli 0157:H7 Specialty [2013.05.09]
Title: Could Adaptable Bacteria Cause Repeat Urinary Tract Infections?
Category: Health News
Created: 5/8/2013 2:36:00 PM
Last Editorial Review: 5/9/2013 12:00:00 AM

Urinary Tract Infections 29 Times More Likely In Schizophrenia Relapse
Source: Schizophrenia News From Medical News Today [2013.04.05]
Schizophrenia patients experiencing relapse are 29 times more likely than healthy individuals to have a urinary tract infection, researchers report. Urinary tract infections, which can cause painful and frequent urination, are common but patients hospitalized for schizophrenia are even more likely to have a UTI than healthy individuals or even others whose illness is under control, said Dr...

Much Greater Risk For Urinary Tract Infections In Schizophrenia Relapse
Source: Schizophrenia News From Medical News Today [2013.04.05]
Schizophrenia patients experiencing relapse are 29 times more likely than healthy individuals to have a urinary tract infection, researchers report. Urinary tract infections, which can cause painful and frequent urination, are common but patients hospitalized for schizophrenia are even more likely to have a UTI than healthy individuals or even others whose illness is under control, said Dr...

Urinary Tract Infection (UTI In Adults)
Source: MedicineNet Bedwetting Specialty [2013.02.01]
Title: Urinary Tract Infection (UTI In Adults)
Category: Diseases and Conditions
Created: 12/31/1997 12:00:00 AM
Last Editorial Review: 2/1/2013 12:00:00 AM

Can Cranberries Fight Urinary Tract Infections?
Source: MedicineNet Acupuncture Specialty [2012.09.12]
Title: Can Cranberries Fight Urinary Tract Infections?
Category: Health News
Created: 9/12/2012 11:00:00 AM
Last Editorial Review: 9/12/2012 12:00:00 AM

more news >>

Published Studies Related to Methenamine Hippurate (Methenamine)

Methenamine hippurate for preventing urinary tract infections. [2012]
CONCLUSIONS: Methenamine hippurate may be effective for preventing UTI

Methenamine hippurate for preventing urinary tract infections. [2007.10.17]
CONCLUSIONS: Methenamine hippurate may be effective for preventing UTI in patients without renal tract abnormalities, particularly when used for short-term prophylaxis. It does not appear to work in patients with neuropathic bladder or in patients who have renal tract abnormalities. The rate of adverse events was low, but poorly described.There is a need for further large well-conducted RCTs to clarify this question, particularly for longer term use for people without neuropathic bladder.

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Clinical Trials Related to Methenamine Hippurate (Methenamine)

Efficacy Study of Acriflavine Hydrochloride + Methenamine + Methylthioninium Chloride vs Placebo for the Rapid Relief of Symptoms Urinary Tract Infection [Not yet recruiting]
The purpose of this study is to evaluate the efficacy of the combination of Acriflavine hydrochloride + Methenamine + Methylthioninium chloride produced by EMS S/A, using the comparator Placebo, the rapid relief of symptoms in uncomplicated lower urinary tract infection in women.

Probiotics as a Prophylactic Aid in Women With Recurrent Urinary Tract Infections (UTI's) [Recruiting]
To investigate if administration of probiotics, either orally or vaginally,

- Can reduce the number of episodes of acute bacterial cystitis and/or

- Has tolerable adverse effect profile

- Improves general QoL in these women

- Improves the immune function and other physiological stress markers

- Reduces inflammation in urinary bladder epithelium

Probiotics for Girls With Recurring Urinary Tract Infections [Not yet recruiting]
Probiotics are dietary supplements containing potentially beneficial bacterial strains such as Lactobacillus. The safety of oral administration of probiotics has been demonstrated in hundreds of studies using adults over the last 30 years. Very few studies have been conducted with children. UTI in girls occur when virulent bacteria migrate from the rectum and colonize the vagina and peri-urethral mucosa, thus gaining access to the bladder.

This study will randomize girls to ARM A (probiotics + placebo) and ARM B (antibiotics + placebo) to determine if UTIs are decreased when the probiotics are given.

Probiotics in Girls With Spina Bifida [Not yet recruiting]
Girls with spina bifida also have bladder problems. This is because they need temporary placement of a tube into the bladder to remove urine. This thin flexible tube is called a catheter. It can increase the risk of having bacteria in the urine. This in turn can lead to urinary tract infection (UTI).

Some girls with spina bifida are given antibiotics. These are medicines used to treat infections caused by bacteria. The medicine is used to prevent UTI. However, long-term treatment with these medicines can have side effects. For example, the bacteria may become resistant to the antibiotics. Also, bacteria in the urine can persist. UTI can still occur in patients on antibiotics.

UTI in girls occurs because bacteria migrate from the rectum to the vagina area. This gives the bacteria access to the bladder. Also, in girls with spina bifida, the access to the bladder is easier because of the catheter.

Probiotics are friendly bacteria. They are available as dietary supplements and as food. They contain helpful bacteria. Yogurt is an example of a food that contains probiotics.

The purpose of this study is to find out, if probiotics taken for 6 months can prevent UTI in girls with spina bifida. We will also try to find out whether changes in urine bacteria are associated with the taking of the probiotics. A vaginal and rectal swab will also be done to find out if taking probiotics has any benefits on preventing bacteria.

Effects of Probiotics on Rheumatoid Arthritis Patients [Recruiting]

more trials >>


Page last updated: 2013-05-09

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