Meprobamate is a white powder with a characteristic odor and a bitter taste. It is slightly soluble in water, freely soluble in acetone and alcohol, and sparingly soluble in ether.
Meprobamate tablets are indicated for the management of anxiety disorders or for the short-term relief of the symptoms of anxiety. Anxiety or tension associated with the stress of everyday life usually do not require treatment with an anxiolytic.
The effectiveness of meprobamate tablets in long-term use, that is, more than 4 months, has not been assessed by systematic clinical studies. The physician should periodically reassess the usefulness of the drug for the individual patient.
Media Articles Related to Meprobamate
Discovery has implications for a number of conditions related to anxiety and trauma
Source: Anxiety / Stress News From Medical News Today [2013.12.06]
A team of Montreal researchers at the IRCM led by Dr. Nabil G. Seidah, in collaboration with Dr. William C. Wetsel's team at Duke University in the United States, discovered that the protein PC7 plays a critical role in the brain by affecting certain types of cognitive performance such as anxiety, learning and emotional memory.
Fear-related behaviours and anxiety disorders: where and how are they controlled?
Source: Anxiety / Stress News From Medical News Today [2013.11.25]
A team of researchers at Inserm led by Cyril Herry (Inserm Unit 862, "Neurocentre Magendie," Bordeaux) has just shown that interneurons located in the forebrain at the level of the prefrontal cortex are heavily involved in the control of fear responses.
Association between size, connectivity of brain region and anxiety level in young children
Source: Anxiety / Stress News From Medical News Today [2013.11.22]
Prolonged stress and anxiety during childhood is a risk factor for developing anxiety disorders and depression later in life. Now, Stanford University School of Medicine researchers have shown that by measuring the size and connectivity of a part of the brain associated with processing emotion - the amygdala - they can predict the degree of anxiety a young child is experiencing in daily life.
Specific area of the brain linked to anxiety disorders in youth
Source: Anxiety / Stress News From Medical News Today [2013.11.21]
Anxiety disorders are common in children and adolescents, affecting up to 25 percent of the youth population. Anxiety causes distress and functional impairment and, if left untreated, can result in bad grades, problems at home and increased rates of psychiatric disorders in adulthood.
Novel method to image worm brain activity and screen early stage compounds aimed at treating autism and anxiety
Source: Anxiety / Stress News From Medical News Today [2013.11.18]
A research team at Worcester Polytechnic Institute (WPI) and The Rockefeller University in New York has developed a novel system to image brain activity in multiple awake and unconstrained worms.
Published Studies Related to Meprobamate
Comparative abuse liability and pharmacological effects of meprobamate, triazolam, and butabarbital. [2003.06]
Implementation of regulations to control the prescribing of benzodiazepines in New York State in 1989 resulted in a 55% decrease in benzodiazepine prescribing, with a concomitant increase in the rates of prescribing older sedative-hypnotic compounds such as butabarbital (30% increase) and meprobamate (125% increase).
Reports of Suspected Meprobamate Side Effects
Toxicity TO Various Agents (28),
Respiratory Arrest (15),
Cardiac Arrest (15),
Accidental Death (14),
Drug Abuse (11),
Completed Suicide (11),
Multiple Drug Overdose Accidental (5),
Pulmonary Congestion (5),
Pulmonary Oedema (4), more >>
Page last updated: 2013-12-06