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Meperidine (Meperidine Hydrochloride) - Summary

 

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MEPERIDINE SUMMARY

MEPERIDINE HYDROCHLORIDE Tablets USP
MEPERIDINE HYDROCHLORIDE Oral Solution USP

Meperidine Hydrochloride Injection, USP 10 mg/mL is a sterile, nonpyrogenic, hypotonic solution of meperidine hydrochloride, USP, in an acetate buffer. This product is to be administered by the intravenous route via a compatible Hospira infusion device. Each mL contains meperidine hydrochloride 10 mg. Sodium acetate, anhydrous 1.5 mg and glacial acetic acid, 0.0012 mL are added as buffers. pH 4.5 (3.5 to 6.0). The solution contains no bacteriostat or antimicrobial agent and is intended only for use as a single-dose unit to provide analgesia via the intravenous route using a compatible Hospira infusion device. Meperidine is classified pharmacologically as a synthetic narcotic analgesic. Meperidine Hydrochloride is ethyl-1-methyl-4-phenylisonipecotate hydrochloride, a white, crystalline substance with a melting point of 186° to 189°C. It is readily soluble in water and has a neutral reaction and a slightly bitter taste. The solution is not decomposed by a short period of boiling.

Meperidine hydrochloride administered by slow intravenous injection is indicated for the relief of moderate to severe pain.

MEPERIDINE NEWS HIGHLIGHTS

Published Studies Related to Meperidine

Intra-articular lidocaine versus intravenous meperidine/diazepam in anterior shoulder dislocation: a randomised clinical trial. [2008.05]

Disposition and clinical outcome after intraperitoneal meperidine and ropivacaine administration during laparoscopic surgery. [2008.01]

Intrathecal meperidine for prevention of shivering during transurethral resection of prostate. [2007.09]

Bupivacaine with meperidine versus bupivacaine with fentanyl for continuous epidural labor analgesia. [2007.06]

The effect of intravenous administration of dexamethasone on postoperative pain, nausea, and vomiting after intrathecal injection of meperidine. [2007.04]

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Clinical Trials Related to Meperidine

Neuraxial Pethidine After Lumbar Surgery Trial [Recruiting]

Comparison Between Nurse-Administered Propofol Sedation and Diazemuls / Pethidine in Outpatient Colonoscopy [Completed]

Epidural Analgesia Versus IV Meperidine for Labor Pain Control [Completed]

Role of Pregabalin in Treatment of Post-Op Pain in Fracture Patients [Recruiting]

Sedation and Analgesia for Transjugular Liver Biopsy: A Randomized Double Blind Placebo Controlled Trial [Completed]

more>>

Page last updated: 2008-06-22

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