MD-76R SUMMARY
MD-76®R
[ DIATRIZOATE MEGLUMINE AND
DIATRIZOATE SODIUM INJECTION U.S.P.]
MD-76R (Diatrizoate Meglumine and Diatrizoate Sodium Injection USP) is a radiopaque contrast agent supplied as a sterile, aqueous solution. Intended for intravascular administration, MD-76R contains 66% w/v 1-deoxy-1-(methylamino)-D-glucitol 3,5-diacetamido-2,4,6, triiodobenzoate (salt) and 10% w/v monosodium 3,5-diacetamido-2,4,6, triiodobenzoate.
MD-76R is indicated in excretion urography, aortography, pediatric angiocardiography, peripheral arteriography, selective renal arteriography, selective visceral arteriography, selective coronary arteriography with or without left ventriculography, contrast enhancement of computed tomographic brain imaging and for intravenous digital subtraction angiography.
MD-76R is also indicated for the contrast enhancement in body computed tomography. (See Clinical Pharmacology). Continuous or multiple scans separated by intervals of 1-3 seconds during the first 30-90 seconds post-injection of the contrast medium (dynamic CT scanning) provide enhancement of diagnostic significance. Subsets of patients in whom delayed body CT scans might be helpful have not been identified. Inconsistent results have been reported and abnormal and normal tissues may be isodense during the time frame used for delayed CT scanning. The risks of such indiscriminate use of contrast media are well known and such use is not recommended. At present, consistent results have been documented using dynamic CT techniques only.
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MD-76R NEWS HIGHLIGHTS Media Articles Related to MD-76R (Diatrizoic Acid / Diatrizoic Acid)
Enigma Diagnostics Announces Successful Evaluation Of The Enigma FL By The UK's Veterinary Laboratories Agency
Source: Infectious Diseases / Bacteria / Viruses News From Medical News Today [2009.07.01]
Enigma Diagnostics Limited, the decentralised and point-of-care molecular diagnostics company, announced successful independent testing for bovine viral diarrhoea (BVD) by the Veterinary Laboratories Agency to evaluate the performance of the Enigma FL (Field Laboratory). BVD is considered to be one of the main threats to cattle (1), affecting the majority of herds in the UK.
New Biomarker Method Could Increase The Number Of Diagnostic Tests For Cancer
Source: Cancer / Oncology News From Medical News Today [2009.06.30]
A team of researchers has demonstrated that a new method for detecting and quantifying protein biomarkers in body fluids may ultimately make it possible to screen multiple biomarkers in hundreds of patient samples, thus ensuring that only the strongest biomarker candidates will advance down the development pipeline.
Survey Of Independent Imaging Centers Reveals That Diagnostic Radiology Networks Play A Critical Role In Channeling Patients
Source: Radiology / Nuclear Medicine News From Medical News Today [2009.06.24]
A survey of 140 independent imaging centers across the United States reveals that diagnostic radiology specialty networks play a critical role in channeling patients to imaging centers for both workers' compensation and health insurance patients.
Exosome Diagnostics And DxS Diagnostic Innovations Collaborate To Develop Blood-Based Tests For Key Cancer Mutations
Source: Blood / Hematology News From Medical News Today [2009.06.23]
Exosome Diagnostics, Inc. ("ExosomeDX") and DxS Ltd. ("DxS") announced that they will collaborate on the development of blood-based companion diagnostics for key cancer gene mutations, such as KRAS, BRAF and EGFR. The collaboration will use DxS' industry leading Scorpions(R) real-time PCR Mutation Test Kits in conjunction with ExosomeDX's xOS(TM) technology which harvests high-quality nucleic acids from blood exosomes.
New Diagnostic Method For Gout: Dual Energy Computed Tomography Instead Of Joint Aspiration
Source: Gout News From Medical News Today [2009.06.05]
The most reliable method of diagnosing gout is to aspirate the joint in order to obtain fluid to verify the presence of monosodiumurate crystals (uric acid). Up to now, computed tomography (CT) has played a limited role in the evaluation of gout, since conventional CT systems cannot reliably verify deposits of uric acid.
Published Studies Related to MD-76R (Diatrizoic Acid / Diatrizoic Acid)
Powdered diatrizoic acid for radiography of the respiratory tract. Part II. Clinical application. [1991.11]
The diagnostic and clinical value of 41 examinations using insufflation and/or inhalation of powdered diatrizoic acid for tracheobronchography, tracheography, laryngography, nasopharyngography, and sinusography was investigated in 35 patients. Diatrizoic acid was found to be useful when applied by insufflation for demonstration of the nasopharynx, trachea and greater bronchi, especially in patients with airway stenosis and low pulmonary reserve...
Powdered diatrizoic acid for radiography of the respiratory tract. Part I. Experimental investigation. [1991.09]
Powdered diatrizoic acid as a contrast medium administered by inhalation and insufflation for visualization of the airways was tested in vitro and in 21 dogs. Good radiopacity of the contrast medium and its antibacterial activity was found in vitro... Histologic and ultrastructural examinations after contrast studies showed phagocytic reaction to diatrizoic acid, transient impairment of production of surfactant, reactive changes of bronchial mucosa, and no fibrotic changes in the long-term observation.
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Page last updated: 2009-07-01
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