ADVERSE REACTIONS
Side effects observed in association with the use of MAXZIDE, other combination products containing triamterene/hydrochlorothiazide, and products containing triamterene or hydrochlorothiazide include the following:
Gastrointestinal: jaundice (intrahepatic cholestatic jaundice), pancreatitis, nausea, appetite disturbance, taste alteration, vomiting, diarrhea, constipation, anorexia, gastric irritation, cramping.
Central Nervous System: drowsiness and fatigue, insomnia, headache, dizziness, dry mouth, depression, anxiety, vertigo, restlessness, paresthesias.
Cardiovascular: tachycardia, shortness of breath and chest pain, orthostatic hypotension (may be aggravated by alcohol, barbiturates or narcotics).
Renal: acute renal failure, acute interstitial nephritis, renal stones composed of triamterene in association with other calculus materials, urine discoloration.
Hematologic: leukopenia, agranulocytosis, thrombocytopenia, aplastic anemia, hemolytic anemia and megaloblastosis.
Ophthalmic: xanthopsia, transient blurred vision.
Hypersensitivity: anaphylaxis, photosensitivity, rash, urticaria, purpura, necrotizing angiitis (vasculitis, cutaneous vasculitis), fever, respiratory distress including pneumonitis.
Other: muscle cramps and weakness, decreased sexual performance and sialadenitis.
Whenever adverse reactions are moderate to severe, therapy should be reduced or withdrawn.
Altered Laboratory Findings:
Serum Electrolytes: hyperkalemia, hypokalemia, hyponatremia, hypomagnesemia, hypochloremia (see WARNINGS, PRECAUTIONS).
Creatinine, Blood Urea Nitrogen: Reversible elevations in BUN and serum creatinine have been observed in hypertensive patients treated with MAXZIDE.
Glucose: hyperglycemia, glycosuria and diabetes mellitus (see PRECAUTIONS).
Serum Uric Acid, PBI and Calcium: (see PRECAUTIONS).
Other: Elevated liver enzymes have been reported in patients receiving MAXZIDE.
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REPORTS OF SUSPECTED MAXZIDE SIDE EFFECTS / ADVERSE REACTIONS
Below is a sample of reports where side effects / adverse reactions may be related to Maxzide. The information is not vetted and should not be considered as verified clinical evidence.
Possible Maxzide side effects / adverse reactions in 62 year old female
Reported by a consumer/non-health professional from United States on 2011-11-17
Patient: 62 year old female
Reactions: Renal Pain, Blood Glucose Increased
Suspect drug(s):
Maxzide
Dosage: 37.5/25mg
Administration route: Oral
Indication: Blood Pressure Increased
Start date: 1991-01-01
Maxzide
Administration route: Oral
Start date: 1991-01-01
Possible Maxzide side effects / adverse reactions in 44 year old female
Reported by a consumer/non-health professional from United States on 2011-11-17
Patient: 44 year old female
Reactions: Hypoglycaemia
Suspect drug(s):
Maxzide
Indication: Hypertension
Start date: 2011-01-01
Maxzide
Start date: 2011-01-01
Other drugs received by patient: Levothyroxine Sodium; Sertraline Hydrochloride
Possible Maxzide side effects / adverse reactions in 64 year old female
Reported by a physician from United States on 2012-01-27
Patient: 64 year old female
Reactions: Photosensitivity Reaction
Suspect drug(s):
Nebivolol
Dosage: 10mg per day
Administration route: Oral
Indication: Hypertension
Start date: 2009-11-11
Nexium
Indication: Product Used FOR Unknown Indication
Maxzide
Indication: Product Used FOR Unknown Indication
Wellbutrin
Indication: Product Used FOR Unknown Indication
Other drugs received by patient: NO Concurrent Medication
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