Maxidex (Dexamethasone Ophthalmic) - Description and Clinical Pharmacology

DESCRIPTION

MAXIDEX® (Dexamethasone Sodium Phosphate) is an adrenocortical steroid prepared as a sterile ophthalmic ointment. The active ingredient is represented by the chemical structure:

Established name:

Dexamethasone Sodium Phosphate

Chemical name:

Pregn-4-ene-3,20-dione,9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonoxy)-, disodium salt, (11β,16α)-.

Each gram contains: Active: Dexamethasone Sodium Phosphate equivalent to Dexamethasone Phosphate 0.5 mg (0.05%) Inactive: Mineral Oil.

White Petrolatum.                                                      DM-00

CLINICAL PHARMACOLOGY

Dexamethasone sodium phosphate suppresses the inflammatory response to a variety of agents and it probably delays or slows healing. No generally accepted explanation of these steroid properties has been advanced.