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Malarone (Atovaquone / Proguanil Hydrochloride) - Summary

 

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MALARONE SUMMARY

MALARONE®
(atovaquone and proguanil hydrochloride)
Tablets
MALARONE®
(atovaquone and proguanil hydrochloride)
Pediatric Tablets

MALARONE (atovaquone and proguanil hydrochloride) is a fixed-dose combination of the antimalarial agents atovaquone and proguanil hydrochloride.

Prevention of Malaria: MALARONE is indicated for the prophylaxis of P. falciparum malaria, including in areas where chloroquine resistance has been reported (see CLINICAL STUDIES).

Treatment of Malaria: MALARONE is indicated for the treatment of acute, uncomplicated P. falciparum malaria. MALARONE has been shown to be effective in regions where the drugs chloroquine, halofantrine, mefloquine, and amodiaquine may have unacceptable failure rates, presumably due to drug resistance.

MALARONE NEWS HIGHLIGHTS

Published Studies Related to Malarone (Atovaquone / Proguanil)

Randomized, double-blind, placebo-controlled study of Malarone for malaria prophylaxis in non-immune Colombian soldiers. [2006.09]

Atovaquone-proguanil for treating uncomplicated malaria. [2005.10.19]

A randomized comparison of artesunate-atovaquone-proguanil versus quinine in treatment for uncomplicated falciparum malaria during pregnancy. [2005.09.01]

Short report: no evidence of cardiotoxicity of atovaquone-proguanil alone or in combination with artesunate. [2005.08]

Malaria prophylaxis for aircrew: safety of atovaquone/proguanil in healthy volunteers under aircraft cabin pressure conditions. [2005.07]

more>>

Clinical Trials Related to Malarone (Atovaquone / Proguanil)

Evaluation of Potential Effect of Artemether - Lumefantrine and Malaria Drugs on Auditory Function [Recruiting]

Azithromycin Plus Chloroquine Versus Atovaquone-Proguanil For The Treatment Of Uncomplicated Plasmodium Falciparum Malaria In South America [Completed]

Chloroquine Alone or in Combination for Malaria in Children in Malawi [Recruiting]

Safety of Artemether - Lumefantrine, and Other Malaria Drugs and Their Effect on the Auditory Function [Terminated]

Drug Interaction Study Between Atovaquone and Antiretroviral Agents in HIV-1 Infected Patients [Recruiting]

more>>

Page last updated: 2006-11-04

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