NEWS HIGHLIGHTSMedia Articles Related to Lybrel (Levonorgestrel / Ethinyl Estradiol)
First scientific data for Lybrel presented at ASRM meeting
Source: The Doctors Lounge - Gynecology
Lybrel is an investigational combination low-dose oral contraceptive designed to be taken daily, 365 days a year.
US funding revamps African contraceptive drive (AFP)
Source: Y! Health News Search RSS Feed [2009.11.18]
AFP - A new 12 million dollar family planning drive launched here Wednesday highlights how Obama administration funding has revamped a contraception drive in Africa and developing states, UN officials said, noting a sharp turnaround from the Bush era.
Terrence Higgins Trust Welcomes Department Of Health Nursing Degree Announcement, UK
Source: HIV / AIDS News From Medical News Today [2009.11.15]
HIV and sexual health charity Terrence Higgins Trust has welcomed the announcement by the Department of Health that all new nurses will be educated to degree level from 2013. Terrence Higgins Trust (THT) currently employs nurses who work in Chlamydia screening programmes for young people, HIV testing clinics and clinics that offer contraception services and screening for sexually transmitted infections.
Published Studies Related to Lybrel (Levonorgestrel / Ethinyl Estradiol)
Cycle control with oral contraceptives containing 20 micrograms of ethinyl estradiol. A multicenter, randomized comparison of levonorgestrel/ethinyl estradiol (100 micrograms/20 micrograms) and norethindrone/ethinyl estradiol (1000 micrograms/20 micrograms). [1999.03]
A randomized, open-label, multicenter study was undertaken to compare the effects of oral contraceptives (OC) containing 100 micrograms levonorgestrel (LNG)/20 micrograms ethinyl estradiol (EE) (Aless/Loette) and 1000 micrograms norethindrone acetate (NETA)/20 micrograms EE (Loestrin Fe 1/20) on menstrual cycle control over four cycles of use...
A continuous regimen of levonorgestrel/ethinyl estradiol for contraception and elimination of menstruation. [2008.03]
Clinicians and patients desiring amenorrhea for therapeutic or social reasons will find continuous-use 90 microg levonorgestrel/20 microg ethinyl estradiol to be an attractive oral contraceptive dosing option. Although other formulations of oral contraceptives can be dosed in a continuous manner off-label, the convenience of a 28-day dose pack represents a major advance that will likely increase acceptability of the strategy...
Evaluation of a continuous regimen of levonorgestrel/ethinyl estradiol for contraception and control of menstrual symptoms. [2008.02]
Considerable recent interest has focused on new methods of delivery of oral contraceptives that reduce or eliminate the hormone-free interval in order to improve convenience and acceptability, but maintain contraceptive efficacy, minimize side effects and reduce or eliminate the frequency of withdrawal bleeding episodes.
Evaluation of a continuous regimen of levonorgestrel/ethinyl estradiol: phase 3 study results. [2006.12]
OBJECTIVE: This study was conducted to evaluate the safety and efficacy of a continuous daily regimen of levonorgestrel (LNG) 90 microg/ethinyl estradiol (EE) 20 microg (continuous LNG/EE)... CONCLUSIONS: Continuous LNG/EE demonstrated a good safety profile and efficacy similar to cyclic OCs. The regimen continuously inhibited menses, increased the incidence of amenorrhea over time and, except for a subset of women, decreased the number of bleeding and spotting days.
Comparison of cycle control with a combined contraceptive vaginal ring and oral levonorgestrel/ethinyl estradiol. [2002.03]
OBJECTIVE: The purpose of this study was to compare cycle control and tolerability of the NuvaRing (NV Organon, Oss, The Netherlands), a novel combined contraceptive vaginal ring, with a standard combined oral contraceptive pill... CONCLUSION: NuvaRing has excellent cycle control and is well tolerated.
Clinical Trials Related to Lybrel (Levonorgestrel / Ethinyl Estradiol)
AZD6140 Oral Contraceptive Interaction Study [Recruiting]
A Study to Evaluate the Efficacy of Seasonique for the Treatment of Cyclic Pelvic Pain [Recruiting]
This study is being conducted to evaluate the effects of treatment with Seasonique an
extended-regimen oral contraceptive that utilizes low dose ethinyl estradiol during the
typical hormone-free interval. Patients will receive 13 weeks of treatment with the option
to extend blinded therapy for an additional 13 weeks. The overall study duration will be 6-9
months. Patients will be required to record menstrual pain in a daily diary.
A Study of Continuous Oral Contraceptives and Doxycycline [Recruiting]
The purpose of this study is to learn if the study drug, doxycycline, can decrease the
amount of unplanned vaginal bleeding that women commonly experience when taking combined
oral contraception (pills with estrogen and progestin) in a continuous fashion (no
hormone-free week). The study drug, doxycycline, is an antibiotic used commonly for many
conditions (i. e. acne, Chlamydia infections, pneumonia) and can be safely used on a daily
basis. Doxycycline has been shown to decrease unplanned vaginal bleeding in progestin-only
contraception but has not been studied in combined hormonal contraception.
Estrogen Treatment in Acromegalic Women [Recruiting]
Oral estrogens may be an effective adjuvant treatment for control of acromegaly in patients
with resistance to somatostatin analogs.
A Multicenter Study to Evaluate the Effects of DR-105 on Bone Mineral Density in Adolescent Females [Recruiting]
This study is being conducted to compare the effects of DR-105 to a 28-day oral
contraceptive regimen on bone mineral density (BMD) in adolescent females. Subjects will be
randomized to either DR-105 or a 28-day oral contraceptive (OC). Subjects not seeking
hormonal contraception who meet eligibility criteria will serve as a control group. Duration
of the study for study subjects will be approximately 13 months.
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