Lunesta Related Published Studies
Well-designed clinical trials related to Lunesta (Eszopiclone)
Effect of eszopiclone on sleep, fatigue, and pain in patients with mucositis associated with hematologic malignancies. [2011.12]
Eszopiclone for the treatment of posttraumatic stress disorder and associated insomnia: a randomized, double-blind, placebo-controlled trial. [2011.07]
A post hoc analysis of the effect of nightly administration of eszopiclone and a selective serotonin reuptake inhibitor in patients with insomnia and anxious depression. [2011.04]
Treatment of insomnia in Parkinson's disease: a controlled trial of eszopiclone and placebo. [2010.08.15]
Economic outcomes of eszopiclone treatment in insomnia and comorbid major depressive disorder. [2010.03]
A 12-week, randomized, double-blind, placebo-controlled study evaluating the effect of eszopiclone 2 mg on sleep/wake function in older adults with primary and comorbid insomnia. [2010.02.01]
Eszopiclone improves insomnia and depressive and anxious symptoms in perimenopausal and postmenopausal women with hot flashes: a randomized, double-blinded, placebo-controlled crossover trial. [2010.02]
A 12-week, randomized, double-blind, placebo-controlled study evaluating the effect of eszopiclone 2 mg on sleep/wake function in older adults with primary and comorbid insomnia. [2010.02]
Treatment of insomnia in Parkinson's disease: a controlled trial of eszopiclone
and placebo. [2010]
Economic outcomes of eszopiclone treatment in insomnia and comorbid major
depressive disorder. [2010]
A 12-week, randomized, double-blind, placebo-controlled study evaluating the
effect of eszopiclone 2 mg on sleep/wake function in older adults with primary
and comorbid insomnia. [2010]
Eszopiclone improves insomnia and depressive and anxious symptoms in
perimenopausal and postmenopausal women with hot flashes: a randomized,
double-blinded, placebo-controlled crossover trial. [2010]
A double-blind study of the influences of eszopiclone on dysgeusia and taste function. [2009.12]
Effects of a short course of eszopiclone on continuous positive airway pressure adherence: a randomized trial. [2009.11.17]
Eszopiclone improves overnight polysomnography and continuous positive airway pressure titration: a prospective, randomized, placebo-controlled trial. [2008.09.01]
Next-day cognition, psychomotor function, and driving-related skills following nighttime administration of eszopiclone. [2008.07]
A polysomnographic placebo-controlled evaluation of the efficacy and safety of eszopiclone relative to placebo and zolpidem in the treatment of primary insomnia. [2008.06.15]
Eszopiclone coadministered with escitalopram in patients with insomnia and comorbid generalized anxiety disorder. [2008.05]
Nightly treatment of primary insomnia with eszopiclone for six months: effect on sleep, quality of life, and work limitations. [2007.08.01]
Evaluation of eszopiclone discontinuation after cotherapy with fluoxetine for insomnia with coexisting depression. [2007.02.15]
Eszopiclone in patients with insomnia during perimenopause and early postmenopause: a randomized controlled trial. [2006.12]
A polysomnography study of eszopiclone in elderly patients with insomnia. [2006.09]
Eszopiclone co-administered with fluoxetine in patients with insomnia coexisting with major depressive disorder. [2006.06.01]
An evaluation of the efficacy and safety of eszopiclone over 12 months in patients with chronic primary insomnia. [2005.11]
A 2-week efficacy and safety study of eszopiclone in elderly patients with primary insomnia. [2005.06.01]
An assessment of the efficacy and safety of eszopiclone in the treatment of transient insomnia in healthy adults. [2005.01]
Efficacy and safety of eszopiclone across 6-weeks of treatment for primary insomnia. [2004.12]
Sustained efficacy of eszopiclone over 6 months of nightly treatment: results of a randomized, double-blind, placebo-controlled study in adults with chronic insomnia. [2003.11.01]
Well-designed clinical trials possibly related to Lunesta (Eszopiclone)
Objective vs. subjective measurements of sleep in depressed insomniacs: first
night effect or reverse first night effect? [2012]
The Movement Disorder Society Evidence-Based Medicine Review Update: Treatments for the non-motor symptoms of Parkinson's disease. [2011.10]
Psychomotor performance after intake of zopiclone compared with intake of ethanol: a randomized, controlled, double-blinded trial. [2011.08]
Dissection of the factors driving the placebo effect in hypnotic treatment of depressed insomniacs. [2011.06]
Mindfulness-based stress reduction versus pharmacotherapy for chronic primary insomnia: a randomized controlled clinical trial. [2011.03]
Dissection of the factors driving the placebo effect in hypnotic treatment of
depressed insomniacs. [2011]
Treatment of insomnia in depressed insomniacs: effects on health-related quality of life, objective and self-reported sleep, and depression. [2010.08.15]
Treatment of insomnia in depressed insomniacs: effects on health-related quality
of life, objective and self-reported sleep, and depression. [2010]
Insomnia severity is an indicator of suicidal ideation during a depression
clinical trial. [2010]
Sedative use during continuous positive airway pressure titration improves subsequent compliance: a randomized, double-blind, placebo-controlled trial. [2009.11]
Interpreting score differences in the Insomnia Severity Index: using health-related outcomes to define the minimally important difference. [2009.10]
Sedative Use During CPAP Titration Improves Subsequent Compliance. A Randomized, Double-Blinded, Placebo-Controlled Trial. [2009.06.30]
Does effective management of sleep disorders reduce depressive symptoms and the risk of depression? [2009]
The CYP2C8 inhibitor gemfibrozil does not increase the plasma concentrations of zopiclone. [2006.08]
Cognitive behavioral therapy vs zopiclone for treatment of chronic primary insomnia in older adults: a randomized controlled trial. [2006.06.28]
Sequential combinations of drug and cognitive behavioral therapy for chronic insomnia: an exploratory study. [2005.12]
Next-day residual effects of hypnotics in DSM-IV primary insomnia: a driving simulator study with simultaneous electroencephalogram monitoring. [2005.10]
Sleep-inducing pharmaceuticals: a comparison of melatonin, zaleplon, zopiclone, and temazepam. [2004.06]
Comparison of lorazepam and zopiclone for insomnia in patients with stroke and brain injury: a randomized, crossover, double-blinded trial. [2004.06]
Impact of melatonin, zaleplon, zopiclone, and temazepam on psychomotor performance. [2003.12]
Effects on postural oscillation and memory functions of a single dose of zolpidem 5 mg, zopiclone 3.75 mg and lormetazepam 1 mg in elderly healthy subjects. A randomized, cross-over, double-blind study versus placebo. [2003.07]
[Study of the real situation of improvement by Zopiclone in treatment of insomnia among persons working during night shifts] [2002.11]
[Comparison of zopiclone and midazolam premedication for preoperative anxiolysis] [2002.10]
Melatonin and zopiclone: the relationship between sleep propensity and body temperature. [2002.05.01]
Differential residual effects of zaleplon and zopiclone on actual driving: a comparison with a low dose of alcohol. [2002.03.15]
Actigraphic assessment of the preoperative hypnotic effects of brotizolam and zopiclone. [2002]
Efficacy and safety of tianeptine in major depression: evidence from a 3-month controlled clinical trial versus paroxetine. [2002]
Melatonin and zopiclone as pharmacologic aids to facilitate crew rest. [2001.11]
[Homeopathic specialties as substitutes for benzodiazepines: double-blind vs. placebo study] [2001.07]
A double-blind, randomized and placebo-controlled study on the polysomnographic withdrawal effects of zopiclone, zolpidem and triazolam in healthy subjects. [2001.06]
A double-blind comparative study of zolpidem versus zopiclone in the treatment of chronic primary insomnia. [2001.05]
The effect of single oral doses of zopiclone on nocturnal melatonin secretion in healthy male volunteers. [2001.05]
The effects of zolpidem and zopiclone on daytime sleepiness and psychomotor performance. [2000.08]
Effects of zolpidem and zopiclone on cognitive and attentional function in young healthy volunteers: an event-related potential study. [2000.02]
Effect of zopiclone and temazepam on sleep EEG parameters, psychomotor and memory functions in healthy elderly volunteers. [2000.01]
Residual effects of hypnotics on disengagement of spatial attention. [2000]
Independent sleep EEG slow-wave and spindle band dynamics associated with 4 weeks of continuous application of short-half-life hypnotics in healthy subjects. [1999.11]
The effects of substituting zopiclone in withdrawal from chronic use of benzodiazepine hypnotics. [1998.12]
Rebound insomnia after hypnotic withdrawal in insomniac outpatients. [1998]
Zopiclone as night medication in rheumatoid arthritis. [1998]
Effect of zopiclone on sleep, night-time ventilation, and daytime vigilance in upper airway resistance syndrome. [1997.11]
Multidrug comparison (lorazepam, triazolam, zolpidem, and zopiclone) in situational insomnia: polysomnographic analysis by means of the cyclic alternating pattern. [1997.06]
Concentrations and effects of zopiclone are greatly reduced by rifampicin. [1997.05]
Is hypnotic withdrawal facilitated by the transitory use of a substitute drug? [1997.01]
A comparison of zopiclone and propiomazine as hypnotics in outpatients: a multicentre, double-blind, randomized, parallel-group comparison of zopiclone and propiomazine in insomniacs. [1997]
Relationship between the effects of a hypnotic drug, zopiclone, on polysomnography and on daytime EEGs. [1997]
Zopiclone pharmacodynamics: by monitoring event-related potentials and psychometric scores. [1996.08]
Effect of itraconazole on the pharmacokinetics and pharmacodynamics of zopiclone. [1996]
[Study of zopiclone with quantitative EEG analysis and topography] [1995.08]
Double-blind comparison of zopiclone and flunitrazepam in elderly insomniacs with special focus on residual effects. [1995]
ECG activity in the sleep of insomniac patients under the influence of lormetazepam and zopiclone. [1995]
Zopiclone as a preoperative night hypnotic: a double-blind comparison with temazepam and placebo. [1994.04]
Zopiclone improves sleep quality and daytime well-being in insomniac patients: comparison with triazolam, flunitrazepam and placebo. [1994.01]
Effects of zopiclone, triazolam, and nitrazepam on standing steadiness. [1994]
Suriclone enhances the actions of chlorpromazine on human psychomotor performance but not on memory or plasma prolactin in healthy subjects. [1994]
Effects of zopiclone on slow wave sleep and spontaneous K-complexes for normal healthy young adults. [1993.12]
Effect of zopiclone on sleep quality, morning stiffness, widespread tenderness and pain and general discomfort in primary fibromyalgia patients. A double-blind randomized trial. [1993.06]
[Periodic discharges of sleep spindles with placebo and zopiclone] [1992.12]
A comparison of efficacy and tolerance of the short acting sedatives midazolam and zopiclone. [1992.10.28]
Interactions and comparative effects of zopiclone, diazepam and lorazepam on psychomotor performance and on elimination pharmacokinetics in healthy volunteers. [1992.02]
Pattern recognition by matched filtering: an analysis of sleep spindle and K-complex density under the influence of lormetazepam and zopiclone. [1992]
Zopiclone in the treatment of sleep abnormalities in fibromyalgia. [1991]
Effects of hypnotics on sleep and psychomotor performance. A double-blind randomised study of lormetazepam, midazolam and zopiclone. [1990.12]
Zopiclone versus flurazepam in insomnia: prolonged administration and withdrawal. [1990.10]
Actions of zopiclone and carbamazepine, alone and in combination, on human skilled performance in laboratory and clinical tests. [1990.09]
Zopiclone and triazolam in insomnia associated with generalized anxiety disorder: a placebo-controlled evaluation of efficacy and daytime anxiety. [1990.07]
A double-blind placebo-controlled trial of zopiclone 7.5 mg and temazepam 20 mg in insomnia. [1990.07]
The effect of zopiclone 7.5 mg on the sleep, mood and performance of shift workers. [1990.04]
A comparison of the efficacy, tolerance and residual effects of zopiclone, flurazepam and placebo in insomniac outpatients. [1990.04]
Zopiclone versus triazolam in insomniac geriatric patients: a specific increase in delta sleep with zopiclone. [1990.04]
Efficacy and safety of zopiclone and triazolam in the treatment of geriatric insomniacs. [1990.04]
A comparison of the efficacy, safety and withdrawal effects of zopiclone and triazolam in the treatment of insomnia. [1990.04]
A comparative study of zopiclone and triazolam in patients with insomnia. [1990.04]
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