Lotensin HCT (Benazepril Hydrochloride / Hydrochlorothiazide) - Summary

LOTENSIN HCT SUMMARY

Lotensin HCT

Benazepril inhibit angiotensin-converting enzyme (ACE). Hydrochlorothiazide is a diuretiuc.

Lotensin HCT is indicated for the treatment of hypertension.

This fixed combination drug is not indicated for the ini-tial therapy of hypertension (DOSAGE AND ADMINISTRATION).

In using Lotensin HCT, consideration should be given to the fact that another angiotensin-converting enzyme inhibitor, captopril, has caused agranulocytosis, particularly in patients with renal impairment or collagen-vascular disease. Available data are insufficient to show that benazepril does not have a similar risk (see WARNINGS, Neutropenia/ Agranulocytosis).

Black patients receiving ACE inhibitors have been reported to have a higher incidence of angioedema compared to nonblacks.

LOTENSIN HCT NEWS HIGHLIGHTS

Media Articles Related to Lotensin HCT (Benazepril / Hydrochlorothiazide)

Pseudotumor Cerebri (Idiopathic Intracranial Hypertension)
Source: MedicineNet Brain Tumor Specialty [2008.09.30]

Study Finds Antioxidant Deficiency Linked To Pulmonary Hypertension
Source: Hypertension News From Medical News Today [2008.09.24]

Vitamin C Might Help Lower Hypertension
Source: MedicineNet High Blood Pressure Specialty [2008.09.22]

Using Honeybee Venom Toxin To Develop A New Tool For Studying Hypertension
Source: Hypertension News From Medical News Today [2008.09.19]

Prehypertension by Age 35 Clogs Arteries
Source: MedicineNet CAT Scan Specialty [2008.07.15]

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Published Studies Related to Lotensin HCT (Benazepril / Hydrochlorothiazide)

Comparison of benazepril-amlodipine and captopril-thiazide combinations in the management of mild-to-moderate hypertension. [2002.06]

Combination of hydrochlorothiazide or benazepril with valsartan in hypertensive patients unresponsive to valsartan alone. [2001.11]

[Antihypertensive action and predictive factors of efficacy of benazepril in mild-to-moderate hypertension: clinical trial in general medical practice on 16,987 patients] [1998.01]

Effects of benazepril and hydrochlorothiazide, given alone and in low- and high-dose combinations, on blood pressure in patients with hypertension. [1996.01]

[Comparison of blood pressure profile during exercise with benazepril 10 mg and benazepril 5 mg/hydrochlorothiazide 6.25 mg fixed combination] [1995.07]

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Clinical Trials Related to Lotensin HCT (Benazepril / Hydrochlorothiazide)

Fed Study of Benazepril HCl and Hydrochlorothiazide Tablets 20 mg/25 mg to Lotensin HCT® Tablets 20 mg/25 mg [Completed]

Fasting Study of Benazepril HCl and Hydrochlorothiazide Tablets 20 mg/25 mg to Lotensin HCT® Tablets 20 mg/25 mg [Completed]

Fed Study of Amlodipine and Benazepril HCl Capsules 10 mg/20 mg to Lotrel® Capsules 10 mg/20 mg [Completed]

Fasting Study of Amlodipine and Benazepril HCl Capsules 10 mg/20 mg to Lotrel® Capsules 10 mg/20 mg [Completed]

Combination of Benazepril Plus Hydrochlorothiazide in Chinese Patients With Mild to Moderate Essential Hypertension [Completed]

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