LORTAB SUMMARY
Hydrocodone bitartrate and acetaminophen is supplied in tablet form for oral administration.
Lortab Tablets are indicated for the relief of moderate to moderately severe pain.
|
NEWS HIGHLIGHTSMedia Articles Related to Lortab (Hydrocodone / Acetaminophen)
hydrocodone/acetaminophen, Vicodin, Vicodin ES, Anexsia, Lorcet, Lorcet Plus, Norco
Source: MedicineNet Coccydynia Specialty [2008.01.07]
Title: hydrocodone/acetaminophen, Vicodin, Vicodin ES, Anexsia, Lorcet, Lorcet Plus, Norco
Category: Medications
Created: 12/31/1997
Last Editorial Review: 1/7/2008
Published Studies Related to Lortab (Hydrocodone / Acetaminophen)
Hydrocodone/acetaminophen and tramadol chlorhydrate combination tablets for the management of chronic cancer pain: a double-blind comparative trial. [2008.01]
OBJETIVES: The purpose of this study was to compare the analgesic efficacy and tolerability of opioids hydrocodone and tramadol in the relief of cancer pain... CONCLUSIONS: There was no superior analgesic efficacy with the administration of hydrocodone/acetaminophen when compared to patients receiving tramadol in the relief of cancer pain. Tramadol produced more mild side effects than hydrocodone.
Tramadol/acetaminophen or hydrocodone/acetaminophen for the treatment of ankle sprain: a randomized, placebo-controlled trial. [2007.04]
STUDY OBJECTIVE: This randomized, multicenter study compares the analgesic efficacy and safety of tramadol/acetaminophen versus hydrocodone/acetaminophen versus placebo for the treatment of acute musculoskeletal pain caused by ankle sprain... CONCLUSION: One or 2 capsules of 37.5 mg tramadol/325 mg acetaminophen and 1 capsule of 7.5 mg hydrocodone/650 mg acetaminophen were well tolerated, had comparable clinical utility, and were more effective than placebo in the management of acute musculoskeletal pain caused by ankle sprain.
Tramadol/Acetaminophen or Hydrocodone/Acetaminophen for the Treatment of Ankle Sprain: A Randomized, Placebo-Controlled Trial. [2006.11.17]
STUDY OBJECTIVE: This randomized, multicenter study compares the analgesic efficacy and safety of tramadol/acetaminophen versus hydrocodone/acetaminophen versus placebo for the treatment of acute musculoskeletal pain caused by ankle sprain... CONCLUSION: One or 2 capsules of 37.5 mg tramadol/325 mg acetaminophen and 1 capsule of 7.5 mg hydrocodone/650 mg acetaminophen were well tolerated, had comparable clinical utility, and were more effective than placebo in the management of acute musculoskeletal pain caused by ankle sprain.
Rofecoxib versus hydrocodone/acetaminophen for postoperative analgesia in functional endoscopic sinus surgery. [2006.04]
OBJECTIVES/HYPOTHESIS: Functional endoscopic sinus surgery (FESS) is less invasive and more tissue sparing than extirpative techniques, with an assumed benefit of diminished postoperative pain. Oral opioids are commonly prescribed after sinus surgery but are associated with adverse effects, including gastrointestinal and neurologic symptoms. Nonopioid analgesics have been suggested to offer similar pain control efficacy with fewer adverse effects. STUDY DESIGN: To investigate postoperative analgesia in FESS, a prospective randomized, double-blinded comparison of hydrocodone/acetaminophen 7.5/750 mg (an opioidderivative) with rofecoxib 50 mg (a cyclooxygenase-2 inhibitor) was performed... CONCLUSIONS: The use of nonopioid analgesics after FESS may provide similar pain control to oral opioids.
Profiling the subjective, psychomotor, and physiological effects of a hydrocodone/acetaminophen product in recreational drug users. [2005.06.01]
BACKGROUND: Hydrocodone (HYD) is a mu opioid agonist. Hydrocodone/acetaminophen HYD/ACET compounds are both widely prescribed and abused prescription painkillers in the United States. In the present study, we profiled the subjective, psychomotor, and physiological effects of the compound. It was of particular interest to determine if HYD/ACET had abuse liability-related subjective effects in a population of recreational drug users... CONCLUSIONS: HYD/ACET produced some abuse liability-related subjective effects in recreational drug users, which is consistent with the widespread non-medical use and abuse of this product.
Clinical Trials Related to Lortab (Hydrocodone / Acetaminophen)
A Study Comparing VicodinŽ CR and NORCOŽ to Placebo in Subjects With Acute Pain Following Bunionectomy [Completed]
The purpose of this study is to evaluate the effectiveness (level of pain control) and safety
of the administration of Extended Release Hydrocodone/Acetaminophen and Immediate Release
Hydrocodone/Acetaminophen with placebo over a 12 hour dosing period in patients who have had
a bunionectomy, and to assess the safety of the drug for 7 days after patients are discharged
from the hospital.
A Study to Evaluate the Interaction Between VicodinŽ CR and Ethanol in Healthy Male and Female Moderate Alcohol Drinkers [Completed]
A Study Comparing the Analgesic Activity of Extended Release Hydrocodone/Acetaminophen (VicodinŽ CR) and Placebo in Subjects With Pain Following Bunionectomy Surgery [Completed]
The purpose of this study is to evaluate the effectiveness (level of pain control) and safety
of the administration of 2 different dose levels of Extended Release
Hydrocodone/Acetaminophen with placebo over a 48 hour dosing period in patients who have had
bunionectomy surgery, and to assess the safety of the drug for 7 days after patients are
discharged from the hospital.
A Study of Extended-Release Hydrocodone/Acetaminophen (Vicodin CRŽ) in Subjects With Acute Pain Following Bunionectomy [Completed]
The purpose of this study is to evaluate the effectiveness (level of pain control) and safety
of the administration of Extended-Release Hydrocodone/Acetaminophen compared to placebo over
a 48 hour dosing period in patients who have had bunionectomy surgery and to assess the
safety of the drug for 7 days after patients are discharged from the hospital.
A Study Comparing the Analgesic Efficacy and Safety of Extended Release Hydrocodone/Acetaminophen (VicodinŽ CR)and Placebo in Subjects With Osteoarthritis [Completed]
The purpose of this study is to evaluate the effectiveness (level of pain control) and safety
of the administration of Extended Release Hydrocodone/Acetaminophen with placebo over a
5-week dosing period in patients with osteoarthritis.
|
PATIENT REVIEWS / RATINGS / COMMENTSBased on a total of 4 ratings/reviews, Lortab has an overall score of 6.25. The effectiveness score is 8.50 and the side effect score is 6. The scores are on ten point scale: 10 - best, 1 - worst. Below are selected reviews: the highest, the median and the lowest rated.
| | Lortab review by 20 year old male patient | | | Rating |
| Overall rating: | |   |
| Effectiveness: | | Highly Effective |
| Side effects: | | Mild Side Effects | | |
Treatment Info |
| Condition / reason: | | Severe low back pain that went down right leg. |
| Dosage & duration: | | 10/500 (dosage frequency: three times daily) for the period of about 6 months |
| Other conditions: | | n/a |
| Other drugs taken: | | Flexeril and Lyrica | | |
Reported Results |
| Benefits: | | The treatment benefits were of a great benefit to me. before i took the lortab i couldn't sleep, work, and i could barely get out of bed the pain was so severe. Before the lortab i did try the flexeril first and it didn't help, then I tried it with the Lyrica that only dulled the pain a little. Then the lortab and it helped tremendously. I started on two times a day after a month went to three and it helped to the point where i could work and I could get out of bed and do things like cut the grass or hiking and just many of other things. My overall experience were tremendous with minimal side effects!!!!! |
| Side effects: | | The Side effects I experienced were minimal such as dizzyness, or lightheaded but addding a little food before my dose would most of time cure the side effects. |
| Comments: | | I was diagnosed with a disc problem that was pinching my nerves in low back. My Sciatica was being pinched by the disc causing my leg to hurt really bad and numbness and tingling were involved. I started taking flexeril first and it by itself wasn't helping. Then i was put on lyrica 2 times daily with the flexerill and it dulled the pain but not much. After that i really didn't want nothing that strong but the pain was severe so the doc put me on lortab 2 times daily to start with and 3 times daily the next month and that helped tremendously. I did physicall therapy for about three months. and now i have minimal back pain and i can function like a normall 20 year old. |
|
| | Lortab review by 37 year old female patient | | | Rating |
| Overall rating: | | |
| Effectiveness: | | Highly Effective |
| Side effects: | | Severe Side Effects | | |
Treatment Info |
| Condition / reason: | | pain from recovering from abdominal surgery |
| Dosage & duration: | | 10 (dosage frequency: every 6 hours) for the period of few weeks |
| Other conditions: | | none |
| Other drugs taken: | | none | | |
Reported Results |
| Benefits: | | treated pain due to an open wound from abdominal surgery |
| Side effects: | | severe nausea, dizziness, lightheaded...I couldn't eat or drink many foods |
| Comments: | | taking pain medication while recovering from surgery...had an open wound with wound vac. The pain was so severe, especially when it came time to change the dressings and clean out the wound in which case I would double up on the medication. It helped with the pain, but also doubled the side effects I was feeling. |
|
| | Lortab review by 37 year old female patient | | | Rating |
| Overall rating: | | |
| Effectiveness: | | Highly Effective |
| Side effects: | | Severe Side Effects | | |
Treatment Info |
| Condition / reason: | | pain from recovering from abdominal surgery |
| Dosage & duration: | | 10 (dosage frequency: every 6 hours) for the period of few weeks |
| Other conditions: | | none |
| Other drugs taken: | | none | | |
Reported Results |
| Benefits: | | treated pain due to an open wound from abdominal surgery |
| Side effects: | | severe nausea, dizziness, lightheaded...I couldn't eat or drink many foods |
| Comments: | | taking pain medication while recovering from surgery...had an open wound with wound vac. The pain was so severe, especially when it came time to change the dressings and clean out the wound in which case I would double up on the medication. It helped with the pain, but also doubled the side effects I was feeling. |
|
|
|
Page last updated: 2008-03-26
|
