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Lopid (Gemfibrozil) - Indications and Dosage



Nitrofurantoin monohydrate/macrocrystals capsules, USP is indicated only for the treatment of acute uncomplicated urinary tract infections (acute cystitis) caused by susceptible strains of Escherichia coli or Staphylococcus saprophyticus.

Nitrofurantoin is not indicated for the treatment of pyelonephritis or perinephric abscesses.

To reduce the development of drug-resistant bacteria and maintain the effectiveness of nitrofurantoin monohydrate/macrocrystals capsules, USP and other antibacterial drugs, nitrofurantoin monohydrate/macrocrystals capsules, USP should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

Nitrofurantoins lack the broader tissue distribution of other therapeutic agents approved for urinary tract infections. Consequently, many patients who are treated with nitrofurantoin monohydrate/macrocrystals capsules, USP, are predisposed to persistence or reappearance of bacteriuria. (See CLINICAL STUDIES.) Urine specimens for culture and susceptibility testing should be obtained before and after completion of therapy. If persistence or reappearance of bacteriuria occurs after treatment with nitrofurantoin monohydrate/macrocrystals capsules, USP, other therapeutic agents with broader tissue distribution should be selected. In considering the use of nitrofurantoin monohydrate/macrocrystals capsules, USP, lower eradication rates should be balanced against the increased potential for systemic toxicity and for the development of antimicrobial resistance when agents with broader tissue distribution are utilized.


Nitrofurantoin monohydrate/macrocrystals capsules, USP should be taken with food.

Adults and Pediatric Patients Over 12 Years: One 100 mg capsule every 12 hours for seven days.


Nitrofurantoin monohydrate/macrocrystals capsules, USP is available as 100 mg opaque black cap and yellow body, size”0” hard gelatin capsules printed with ‘ RX 518’ in white ink on cap and in black ink on body containing off-white to light yellow powder and a yellow tablet debossed with ‘ RX595’ on one side and plain on the other side.

NDC 63304-518-20 Bottles of 20

NDC 63304-518-05 Bottles of 500

Store at 20 - 25° C (68 - 77° F) [See USP Controlled Room Temperature].

Dispense in a tight, light resistant container.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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