LOMOTIL SUMMARY
Lomotil® Cv
(diphenoxylate hydrochloride
and atropine sulfate tablets, USP)
Tablets
(diphenoxylate hydrochloride
and atropine sulfate oral solution, USP)
Liquid
Each Lomotil tablet and each 5 ml of Lomotil liquid for oral use contains:
diphenoxylate hydrochloride 2.5 mg
atropine sulfate................. 0.025 mg
Diphenoxylate hydrochloride is an antidiarrheal.
Atropine sulfate is an anticholinergic.
A subtherapeutic amount of atropine sulfate is present to discourage deliberate overdosage.
Lomotil (diphenoxylate/atropine) is indicated for the following:
Lomotil is effective as adjunctive therapy in the management of diarrhea.
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NEWS HIGHLIGHTSMedia Articles Related to Lomotil (Diphenoxylate / Atropine)
Health Tip: When Infants Get Diarrhea (HealthDay)
Source: Y! Health News Search RSS Feed [2009.11.19]
HealthDay - (HealthDay News) -- Diarrhea in infants is common, often a
quick bout caused by a virus. But in some cases among young children,
diarrhea can quickly become dangerous, says the U.S. National Library of
Medicine.
Health Tip: When Infants Get Diarrhea
Source: MedicineNet Dehydration Specialty [2009.11.19]
Title: Health Tip: When Infants Get Diarrhea
Category: Health News
Created: 11/19/2009 8:10:00 AM
Last Editorial Review: 11/19/2009
Study Examines Campaign To Increase Use Of Zinc To Prevent Childhood Diarrhea
Source: GastroIntestinal / Gastroenterology News From Medical News Today [2009.11.05]
Scientific American reports on a multiyear PLoS Medicine study, published on Monday, which "followed a nationwide public health campaign to increase zinc use for childhood diarrhea in Bangladesh." "A 10-day course of zinc tablets ...
Also In Global Health News: Breast Cancer In Developing World; Burkina Faso ITN Distribution; Diarrhea In People Over Age Five; Gates Q&A
Source: Tropical Diseases News From Medical News Today [2009.11.04]
Researchers Highlight 'Troubling Increase' In Breast Cancer In Developing Countries "International cancer specialists meet this week to plan an assault on a troubling increase of breast cancer in developing countries, where nearly two-thirds of women aren't diagnosed until it has spread through their bodies," the Associated Press reports.
New Research Reveals The Cause Of Common Chronic Diarrhea
Source: Endocrinology News From Medical News Today [2009.11.03]
A common type of chronic diarrhoea may be caused by a hormone deficiency, according to new research published in the November issue of Clinical Gastroenterology and Hepatology.
Published Studies Related to Lomotil (Diphenoxylate / Atropine)
Pretreatment with Diphenoxylate Hydrochloride/Atropine Sulfate (Lomotil) does not Decrease Physiologic Bowel FDG Activity on PET/CT Scans of the Abdomen and Pelvis. [2009.03]
CONCLUSIONS: Pretreatment with Lomotil prior to PET/CT scanning confers no benefit toward the reduction of physiologic FDG uptake by the small bowel and colon.
Are one or two dangerous? Diphenoxylate-atropine exposure in toddlers. [2008.01]
Lomotil (Pfizer Inc., New York, NY) (diphenoxylate-atropine) is said to be potentially toxic to toddlers with exposure to as little as one to two tablets. A review of the data on diphenoxylate-atropine poisonings from the American Association of Poison Control Centers annual reports, review articles, and case series disputes this view.
Clinical Trials Related to Lomotil (Diphenoxylate / Atropine)
Diphenoxylate / Atropine to Decrease FDG Activity During F-18 FDG PET [Completed]
2-[18F]-fluoro-2-deoxyD-glucose positron emission tomography (FDG PET) has proven to be a
valuable clinical tool for the staging and surveillance of lymphoma. 1-6 Occasionally, lymph
nodes in the mesentery and retroperitoneum can be difficult to distinguish from normal bowel
activity on PET scans despite three-plane and cine maximal image projection (MIP) imaging.
This uncertainty limits the clinical usefulness of PET in some cases of lymphoma. 7-8 In
addition, bowel activity can also hinder interpretation of PET scans in other types of solid
tumors including melanoma and colorectal cancer. 6,9,10 Our goal is to determine how well
diphenoxylate/atropine 5mg/0. 05mg (Lomotil) decreases bowel activity and how this decrease
impacts clinical decision-making, specifically for lymphoma staging and surveillance. This is
a prospective, randomized, double-blinded study involving 60 patients undergoing PET scans
for newly diagnosed or recurrent, untreated lymphoma.
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