DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more

Lomotil (Diphenoxylate Hydrochloride / Atropine Sulfate) - Summary



LOMOTIL (DIPHENOXYLATE/ATROPINE) contains diphenoxylate hydrochloride, an antidiarrheal and atropine sulfate, an anticholinergic.

LOMOTIL (DIPHENOXYLATE/ATROPINE) is indicated for the following:

Lomotil is effective as adjunctive therapy in the management of diarrhea.

See all Lomotil indications & dosage >>


Media Articles Related to Lomotil (Diphenoxylate / Atropine)

IBS-D (Irritable Bowel Syndrome with Diarrhea)
Source: MedicineNet Constipation Specialty [2017.09.22]
Title: IBS-D (Irritable Bowel Syndrome with Diarrhea)
Category: Diseases and Conditions
Created: 8/10/2016 12:00:00 AM
Last Editorial Review: 9/22/2017 12:00:00 AM

Source: MedicineNet Addison Disease Specialty [2017.03.21]
Title: Diarrhea
Category: Symptoms and Signs
Created: 10/13/2003 12:00:00 AM
Last Editorial Review: 3/21/2017 12:00:00 AM

Travelers' Diarrhea
Source: MedicineNet attapulgite Specialty [2016.03.16]
Title: Travelers' Diarrhea
Category: Diseases and Conditions
Created: 4/3/1999 12:00:00 AM
Last Editorial Review: 3/16/2016 12:00:00 AM

New Meds OK'd for Hard-to-Treat IBS With Diarrhea
Source: MedicineNet alosetron Specialty [2015.05.29]
Title: New Meds OK'd for Hard-to-Treat IBS With Diarrhea
Category: Health News
Created: 5/29/2015 12:00:00 AM
Last Editorial Review: 5/29/2015 12:00:00 AM

A 37-Year-Old Woman With Bloating and Itchy Vesicles
Source: Medscape Allergy & Clinical Immunology Headlines [2017.09.29]
A 37-year-old woman presents with diarrhea and bloating over the past few years. She also reports itchy vesicles around the extensor surfaces of her arms and legs. What condition is responsible?

more news >>

Published Studies Related to Lomotil (Diphenoxylate / Atropine)

Pretreatment with Diphenoxylate Hydrochloride/Atropine Sulfate (Lomotil) does not Decrease Physiologic Bowel FDG Activity on PET/CT Scans of the Abdomen and Pelvis. [2009.03]
CONCLUSIONS: Pretreatment with Lomotil prior to PET/CT scanning confers no benefit toward the reduction of physiologic FDG uptake by the small bowel and colon.

Are one or two dangerous? Diphenoxylate-atropine exposure in toddlers. [2008.01]
Lomotil (Pfizer Inc., New York, NY) (diphenoxylate-atropine) is said to be potentially toxic to toddlers with exposure to as little as one to two tablets. A review of the data on diphenoxylate-atropine poisonings from the American Association of Poison Control Centers annual reports, review articles, and case series disputes this view.

more studies >>

Clinical Trials Related to Lomotil (Diphenoxylate / Atropine)

Diphenoxylate / Atropine to Decrease FDG Activity During F-18 FDG PET [Completed]
2-[18F]-fluoro-2-deoxyD-glucose positron emission tomography (FDG PET) has proven to be a valuable clinical tool for the staging and surveillance of lymphoma. 1-6 Occasionally, lymph nodes in the mesentery and retroperitoneum can be difficult to distinguish from normal bowel activity on PET scans despite three-plane and cine maximal image projection (MIP) imaging. This uncertainty limits the clinical usefulness of PET in some cases of lymphoma. 7-8 In addition, bowel activity can also hinder interpretation of PET scans in other types of solid tumors including melanoma and colorectal cancer. 6,9,10 Our goal is to determine how well diphenoxylate/atropine 5mg/0. 05mg (Lomotil) decreases bowel activity and how this decrease impacts clinical decision-making, specifically for lymphoma staging and surveillance. This is a prospective, randomized, double-blinded study involving 60 patients undergoing PET scans for newly diagnosed or recurrent, untreated lymphoma.

more trials >>

Reports of Suspected Lomotil (Diphenoxylate / Atropine) Side Effects

Chronic Obstructive Pulmonary Disease (23)Emphysema (23)Amnesia (22)Bedridden (21)Diarrhoea (17)Nausea (8)Syncope (7)Fatigue (6)Incorrect Dose Administered (6)Hyponatraemia (6)more >>

Page last updated: 2017-09-29

-- advertisement -- The American Red Cross
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2017