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Lomotil (Diphenoxylate Hydrochloride / Atropine Sulfate) - Summary

 
 



LOMOTIL SUMMARY

LOMOTIL (DIPHENOXYLATE/ATROPINE) contains diphenoxylate hydrochloride, an antidiarrheal and atropine sulfate, an anticholinergic.

LOMOTIL (DIPHENOXYLATE/ATROPINE) is indicated for the following:

Lomotil is effective as adjunctive therapy in the management of diarrhea.


See all Lomotil indications & dosage >>

NEWS HIGHLIGHTS

Media Articles Related to Lomotil (Diphenoxylate / Atropine)

When to Call the Doctor for Fever, Nausea, Diarrhea, Colds, and Coughs
Source: MedicineNet Bruises Specialty [2016.12.01]
Title: When to Call the Doctor for Fever, Nausea, Diarrhea, Colds, and Coughs
Category: Doctor's & Expert's views on Symptoms
Created: 12/20/2010 12:00:00 AM
Last Editorial Review: 12/1/2016 12:00:00 AM

IBS-D (Irrititable Bowel Syndrome with Diarrhea)
Source: MedicineNet Laxatives For Constipation Specialty [2016.08.10]
Title: IBS-D (Irrititable Bowel Syndrome with Diarrhea)
Category: Diseases and Conditions
Created: 8/10/2016 12:00:00 AM
Last Editorial Review: 8/10/2016 12:00:00 AM

Addicts Using Diarrhea Drug Imodium to Get High
Source: MedicineNet Poison Control Centers Specialty [2016.05.06]
Title: Addicts Using Diarrhea Drug Imodium to Get High
Category: Health News
Created: 5/5/2016 12:00:00 AM
Last Editorial Review: 5/6/2016 12:00:00 AM

Travelers' Diarrhea
Source: MedicineNet Giardia Lamblia Specialty [2016.03.16]
Title: Travelers' Diarrhea
Category: Diseases and Conditions
Created: 4/3/1999 12:00:00 AM
Last Editorial Review: 3/16/2016 12:00:00 AM

Diarrhea
Source: MedicineNet Giardia Lamblia Specialty [2015.10.29]
Title: Diarrhea
Category: Diseases and Conditions
Created: 12/31/1997 12:00:00 AM
Last Editorial Review: 10/29/2015 12:00:00 AM

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Published Studies Related to Lomotil (Diphenoxylate / Atropine)

Pretreatment with Diphenoxylate Hydrochloride/Atropine Sulfate (Lomotil) does not Decrease Physiologic Bowel FDG Activity on PET/CT Scans of the Abdomen and Pelvis. [2009.03]
CONCLUSIONS: Pretreatment with Lomotil prior to PET/CT scanning confers no benefit toward the reduction of physiologic FDG uptake by the small bowel and colon.

Are one or two dangerous? Diphenoxylate-atropine exposure in toddlers. [2008.01]
Lomotil (Pfizer Inc., New York, NY) (diphenoxylate-atropine) is said to be potentially toxic to toddlers with exposure to as little as one to two tablets. A review of the data on diphenoxylate-atropine poisonings from the American Association of Poison Control Centers annual reports, review articles, and case series disputes this view.

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Clinical Trials Related to Lomotil (Diphenoxylate / Atropine)

Diphenoxylate / Atropine to Decrease FDG Activity During F-18 FDG PET [Completed]
2-[18F]-fluoro-2-deoxyD-glucose positron emission tomography (FDG PET) has proven to be a valuable clinical tool for the staging and surveillance of lymphoma. 1-6 Occasionally, lymph nodes in the mesentery and retroperitoneum can be difficult to distinguish from normal bowel activity on PET scans despite three-plane and cine maximal image projection (MIP) imaging. This uncertainty limits the clinical usefulness of PET in some cases of lymphoma. 7-8 In addition, bowel activity can also hinder interpretation of PET scans in other types of solid tumors including melanoma and colorectal cancer. 6,9,10 Our goal is to determine how well diphenoxylate/atropine 5mg/0. 05mg (Lomotil) decreases bowel activity and how this decrease impacts clinical decision-making, specifically for lymphoma staging and surveillance. This is a prospective, randomized, double-blinded study involving 60 patients undergoing PET scans for newly diagnosed or recurrent, untreated lymphoma.

more trials >>

Reports of Suspected Lomotil (Diphenoxylate / Atropine) Side Effects

Chronic Obstructive Pulmonary Disease (23)Emphysema (23)Amnesia (22)Bedridden (21)Diarrhoea (17)Nausea (8)Syncope (7)Fatigue (6)Incorrect Dose Administered (6)Hyponatraemia (6)more >>


Page last updated: 2016-12-01

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