LO Ovral (Norgestrel / Ethinyl Estradiol) - Clinical Pharmacology

CLINICAL PHARMACOLOGY

MODE OF ACTION

Combination oral contraceptives act by suppression of gonadotropins. Although the primary mechanism of this action is inhibition of ovulation, other alterations include changes in the cervical mucus (which increase the difficulty of sperm entry into the uterus) and the endometrium (which reduce the likelihood of implantation).