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Lithium Carbonate (Lithium Carbonate) - Description and Clinical Pharmacology


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Each capsule for oral administration contains 150 mg, 300 mg or 600 mg of lithium carbonate. In addition, each capsule contains the following inactive ingredient:

150 mg: Talc.

300 mg: Talc.

600 mg: Colloidal Silicon Dioxide, Stearic Acid and Talc.

Capsule shell for the 150 mg potency contains: Gelatin and Titanium Dioxide.

Capsule shell for the 300 mg potency contains: D&C Yellow #10, FD&C Green #3, FD&C Red #40, FD&C Yellow #6, Gelatin and Titanium Dioxide.

Capsule shell for the 600 mg potency contains: Titanium Dioxide, Gelatin and FD&C Red #40.

The printing ink contains: D&C Yellow #10, FD&C Blue #1, FD&C Blue #2, FD&C Red #40, n-Butyl Alcohol, Pharmaceutical Glaze, Propylene Glycol, SDA-3A Alcohol, and Synthetic Black Iron Oxide.

Lithium is an element of the alkali-metal group with atomic number 3, atomic weight 6.94 and an emission line at 671 nm on the flame photometer.

Lithium Carbonate is a white, light, alkaline powder with molecular formula Li2CO3 and molecular weight 73.89.


Preclinical studies have shown that lithium alters sodium transport in nerve and muscle cells and effects a shift toward intraneuronal metabolism of catecholamines, but the specific biochemical mechanism of lithium action in mania is unknown.

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