LidoSite™ Topical System
comprised of the
LidoSite ™ Patch
(Lidocaine HCl / Epinephrine topical iontophoretic patch) 10%/0.1%
LidoSite ™ Controller
The LidoSite™ Topical System (LidoSite™ System) consists of a LidoSite™ Patch and a LidoSite™ Controller, a portable microprocessor-controlled battery-powered DC current source. The LidoSite™ System delivers lidocaine and epinephrine simultaneously by topical iontophoresis to achieve dermal analgesia on intact skin. Iontophoresis is based on the principle that a soluble salt or drug can be transported across the skin barrier as a part of an electric current induced in the skin.
LidoSite™ System is a topical local anesthetic delivery system indicated for use on normal intact skin to provide local analgesia for superficial dermatological procedures such as venipuncture, intravenous cannulation, and laser ablation of superficial skin lesions.
LidoSite™ System is indicated for use on patients 5 years of age and older.
Media Articles Related to Lidosite (Lidocaine / Epinephrine Iontophoresis)
Are the cognitive side effects of anesthesia overlooked?
Source: Medical Devices / Diagnostics News From Medical News Today [2014.08.19]
Although guidelines are commonly in place to minimize pain-related side effects of anesthesia, a new survey finds that less attention is paid to the risk of cognitive side effects.
For pediatric knee surgery, regional anesthesia reduces pain, speeds recovery
Source: Bones / Orthopedics News From Medical News Today [2014.08.14]
A recent study of an ultrasound-guided regional anesthesia technique, called femoral nerve block, shows that it leads to less opioid use and allows the majority of patients to go home within hours of...
Dopamine release from ventral tegmental area may help speed emergence from anesthesia, avoid complications
Source: Pain / Anesthetics News From Medical News Today [2014.07.31]
Stimulating one of two dopamine-producing regions in the brain was able to arouse animals receiving general anesthesia with either isoflurane or propofol.
The disruptive effects of anesthesia on brain cell connections are likely temporary
Source: Pain / Anesthetics News From Medical News Today [2014.07.30]
A study of juvenile rat brain cells suggests that the effects of a commonly used anesthetic drug on the connections between brain cells are temporary.
'Ramp control' algorithm simplifies preoperative test for patients with severe sleep apnea
Source: Pain / Anesthetics News From Medical News Today [2014.08.01]
New anesthesia technique helps show cause of obstruction in sleep apneaA simplified anesthesia procedure may enable more widespread use of preoperative testing to demonstrate the cause of airway...
Clinical Trials Related to Lidosite (Lidocaine / Epinephrine Iontophoresis)
Gluing Lacerations Utilizing Epinephrine [Recruiting]
Minor lacerations are a commonly treated injury in the paediatric emergency department .
Over the past decade, standard closure of these lacerations has evolved from suture repair
to closure with tissue adhesive (also referred to as "skin glue"). Local anaesthetic is not
routinely used during application of skin glue as it was with sutures. There are, however,
several potential advantages to pre-treating wounds with topical LET
(Lidocaine-Epinephrine-Tetracaine), a liquid gel with anaesthetic and vasoconstrictive
properties. Some believe LET can improve patient comfort, increase the ease of glue
application, and lead to better healing when used on lacerations being repaired with tissue
adhesive. This study aims to address the question of whether or not pre-treatment with LET
improves outcomes in minor lacerations repaired with skin glue. The primary hypothesis is
that pre-treatment of minor lacerations with LET will decrease pain (as measured on a Visual
Analog Scale) during repair with tissue adhesive.
Comparison of Epinephrine-lidocaine Solution and Dexmedetomidine -Lidocaine Solution [Not yet recruiting]
Scalp infiltration with Epinephrine- containing lidocaine solution is common method for
craniotomy but it may result in transient but significant hypotension in patients undergoing
neurosurgery. Dexmedetomidine, a potent alpha2 adrenoceptor agonist which dose-dependently
reduces arterial blood pressure and heart rate, decreases the hemodynamic and catecholamine
response, and dexmedetomidine has an effect of peripheral vasoconstriction thus it is thus
theologically appropriate for reducing bleeding during scalp incision in craniotomy.
The aim of this study is to compare the effect of dexmedetomidine-lidocaine solution on
hemodynamic response, scalp bleeding to epinephrine-lidocaine solution.