LidoSite™ Topical System
comprised of the
LidoSite ™ Patch
(Lidocaine HCl / Epinephrine topical iontophoretic patch) 10%/0.1%
LidoSite ™ Controller
The LidoSite™ Topical System (LidoSite™ System) consists of a LidoSite™ Patch and a LidoSite™ Controller, a portable microprocessor-controlled battery-powered DC current source. The LidoSite™ System delivers lidocaine and epinephrine simultaneously by topical iontophoresis to achieve dermal analgesia on intact skin. Iontophoresis is based on the principle that a soluble salt or drug can be transported across the skin barrier as a part of an electric current induced in the skin.
LidoSite™ System is a topical local anesthetic delivery system indicated for use on normal intact skin to provide local analgesia for superficial dermatological procedures such as venipuncture, intravenous cannulation, and laser ablation of superficial skin lesions.
LidoSite™ System is indicated for use on patients 5 years of age and older.
Media Articles Related to Lidosite (Lidocaine / Epinephrine Iontophoresis)
Stimulating a specific brain pathway may induce active emergence from anesthesia
Source: Neurology / Neuroscience News From Medical News Today [2014.07.24]
Researchers may be one step closer to better understanding how anesthesia works.
Study finds low hand hygiene compliance rates during anesthesia administration
Source: Pain / Anesthetics News From Medical News Today [2014.07.02]
Anesthesia providers are missing opportunities to clean their hands during surgical procedures, according to a study published in the American Journal of Infection Control, the official publication...
Use of regional anesthesia during hip fracture surgery not associated with lower risk of death
Source: Pain / Anesthetics News From Medical News Today [2014.06.24]
Among more than 56,000 adults undergoing hip repair between 2004 and 2011, the use of regional anesthesia compared with general anesthesia was not associated with a lower risk of death at 30 days...
Anesthesia May Harm Children's Brains
Source: MedicineNet Ear Tubes Specialty [2012.08.20]
Title: Anesthesia May Harm Children's Brains
Category: Health News
Created: 8/20/2012 11:00:00 AM
Last Editorial Review: 8/20/2012 12:00:00 AM
Hydroxyethyl starch in resuscitation fluid has direct harmful effects on kidney cells
Source: Urology / Nephrology News From Medical News Today [2014.07.14]
The increased risk of kidney injury related to the use of hydroxyethyl starch (HES) in resuscitation fluids reflects the mass of HES molecules, according to a report in Anesthesia & Analgesia...
Clinical Trials Related to Lidosite (Lidocaine / Epinephrine Iontophoresis)
Gluing Lacerations Utilizing Epinephrine [Recruiting]
Minor lacerations are a commonly treated injury in the paediatric emergency department .
Over the past decade, standard closure of these lacerations has evolved from suture repair
to closure with tissue adhesive (also referred to as "skin glue"). Local anaesthetic is not
routinely used during application of skin glue as it was with sutures. There are, however,
several potential advantages to pre-treating wounds with topical LET
(Lidocaine-Epinephrine-Tetracaine), a liquid gel with anaesthetic and vasoconstrictive
properties. Some believe LET can improve patient comfort, increase the ease of glue
application, and lead to better healing when used on lacerations being repaired with tissue
adhesive. This study aims to address the question of whether or not pre-treatment with LET
improves outcomes in minor lacerations repaired with skin glue. The primary hypothesis is
that pre-treatment of minor lacerations with LET will decrease pain (as measured on a Visual
Analog Scale) during repair with tissue adhesive.
Comparison of Epinephrine-lidocaine Solution and Dexmedetomidine -Lidocaine Solution [Not yet recruiting]
Scalp infiltration with Epinephrine- containing lidocaine solution is common method for
craniotomy but it may result in transient but significant hypotension in patients undergoing
neurosurgery. Dexmedetomidine, a potent alpha2 adrenoceptor agonist which dose-dependently
reduces arterial blood pressure and heart rate, decreases the hemodynamic and catecholamine
response, and dexmedetomidine has an effect of peripheral vasoconstriction thus it is thus
theologically appropriate for reducing bleeding during scalp incision in craniotomy.
The aim of this study is to compare the effect of dexmedetomidine-lidocaine solution on
hemodynamic response, scalp bleeding to epinephrine-lidocaine solution.