Lidocaine Hydrochloride Injection, intramuscular for Cardiac Arrhythmias, is a non-pyrogenic, sterile solution prepared from lidocaine hydrochloride, USP and Water for Injection.
Lidocaine hydrochloride is indicated in the management of cardiac arrhythmias, particularly those of ventricular origin, such as occur with acute myocardial infarction.
The selection of the intramuscular route of administration (single dose) is justified in the following circumstances:
- By a physician in whose opinion the potential benefits outweigh the possible risks even when ECG equipment is not available to verify the arrhythmia.
- By, or under the supervision of, a physician, including mobile coronary care units, when facilities for intravenous administration are not readily available, or under circumstances where maintaining continuous intravenous therapy is difficult or impossible.
- For use in the pre-hospital phase of suspected acute myocardial infarction by a patient who has transmitted his electrocardiogram with a CardioBeeper®, whose electrocardiogram demonstrates the presence of a ventricular arrhythmia and who is instructed by qualified medical personnel to self-administer the LidoPen® Auto-Injector.
Media Articles Related to Lidopen (Lidocaine)
While under general anesthesia rats' brains may 'remember' odor experienced
Source: Pain / Anesthetics News From Medical News Today [2014.03.19]
Rats' brains may remember odors they were exposed to while deeply anesthetized, suggests research in rats published in the April issue of Anesthesiology.
Anesthesia May Harm Children's Brains
Source: MedicineNet Ear Tubes Specialty [2012.08.20]
Title: Anesthesia May Harm Children's Brains
Category: Health News
Created: 8/20/2012 11:00:00 AM
Last Editorial Review: 8/20/2012 12:00:00 AM
A biomarker for postoperative cognitive dysfunction - aspartic acid in the hippocampus:
Source: Pain / Anesthetics News From Medical News Today [2014.04.01]
Postoperative cognitive dysfunction is the deterioration of cognitive performance after anesthesia and surgery, and manifests as impairments in short-term memory, concentration, language...
Comparable outcomes for outpatient, inpatient orthopaedic surgeries
Source: Arthritis / Rheumatology News From Medical News Today [2014.03.15]
As the effectiveness of anesthesia, pain management and rehabilitation continues to improve, more orthopaedic procedures are being done on an outpatient basis.
Published Studies Related to Lidopen (Lidocaine)
Cervical lidocaine for IUD insertional pain: a randomized controlled trial. 
intracervical 2% lidocaine gel for pain relief with IUD insertion... CONCLUSION: Topical or intracervical 2% lidocaine gel prior to IUD insertion does
Treatment for postoperative wound pain in gynecologic laparoscopic surgery:
topical lidocaine patches. 
CONCLUSIONS: Topical lidocaine patches at the laparoscopic port sites reduced
Lidocaine/tetracaine patch (Rapydan) for topical anaesthesia before arterial
access: a double-blind, randomized trial. 
non-inferior to subcutaneous local anaesthetic... CONCLUSIONS: Both the lidocaine/tetracaine patch and subcutaneous injection of
Intravenous lidocaine for the treatment of background or procedural burn pain. 
CONCLUSIONS: As current clinical evidence is based on only one single
Systemic lidocaine to improve postoperative quality of recovery after ambulatory
laparoscopic surgery. 
outpatient laparoscopic surgery... CONCLUSIONS: Systemic lidocaine improves postoperative quality of recovery in
Clinical Trials Related to Lidopen (Lidocaine)
J-Tip® Jet Injection of 1% Buffered Lidocaine or Saline Versus 4% Lidocaine Cream Before Venipuncture or IV Insertion [Not yet recruiting]
To measure and compare pain associated with venipuncture and peripheral intravenous catheter
insertion among pediatric emergency department patients randomized to treatment with one of
three different pain-reduction strategies: J-Tip® jet injection of 1% buffered lidocaine,
J-Tip® jet injection of sterile saline, or application of 4% lidocaine topical cream. The
investigators hypothesize that J-Tip® jet injection of 1% buffered lidocaine will provide
superior local anesthesia compared to saline or lidocaine cream.
Lidocaine and Ketamine in Abdominal Surgery [Recruiting]
This study is being done to determine if combined infusions of lidocaine and ketamine is
better than a lidocaine or ketamine infusion alone, or to placebo in improving recovery
after abdominal hysterectomy. Participants will be randomized into one of four groups.
Evaluations will be done through walking tests, pain and fatigue questionnaires and blood
A Study to Characterize the Phenotype in Patients With Morton's Neuroma and to Explore the Effect of Local Administration of Xylocaine (Lidocaine) [Recruiting]
To characterize the phenotype in patients with Morton's neuroma and to explore the effect of
local administration of Xylocaine (lidocaine)
Intrauterine Lidocaine Infusion for Essure Sterilization Procedures [Recruiting]
The purpose of this study is to assess the level of pain women experience with an Essure
procedure and the effect that lidocaine might have on that pain. We will also assess the
absorption of lidocaine in the uterus by measuring lidocaine levels in the blood.
The Effect of Intravenous Lidocaine and Intraperitoneal Lidocaine Irrigation on Pain After Laparoscopic Cholecystectomy [Recruiting]
This prospective randomized study aims to comparison the effectiveness of intravenous
lidocaine injection and intraperitoneam lidocaine irrigation on the relief of pain in
patients undergoing laparoscopic cholecystectomy.
A total of 83 patients will be randomized into one of three groups (group C or group I or
group P) based on Excel number generation.
Patients in group C will receive normal saline intravenous injection, and patients in group
I will receive an intravenous bolus injection of 1. 5 mg/kg lidocaine followed by a
continuous lidocaine infusion of 2 mg/kg/hr.
Patients in group P will receive intraperitoneal lidocaine irrigation with 3. 5 mg/kg
lidocaine and normal saline 100cc.
Visual analogue scale pain scores, fentanyl consumption and the frequency at which patients
pushed the button (FPB) of a patient-controlled analgesia system will be recorded at 2, 4,
8, 12, 24, 48 hours postoperatively.