Lidocaine Hydrochloride Injection, intramuscular for Cardiac Arrhythmias, is a non-pyrogenic, sterile solution prepared from lidocaine hydrochloride, USP and Water for Injection.
Lidocaine hydrochloride is indicated in the management of cardiac arrhythmias, particularly those of ventricular origin, such as occur with acute myocardial infarction.
The selection of the intramuscular route of administration (single dose) is justified in the following circumstances:
- By a physician in whose opinion the potential benefits outweigh the possible risks even when ECG equipment is not available to verify the arrhythmia.
- By, or under the supervision of, a physician, including mobile coronary care units, when facilities for intravenous administration are not readily available, or under circumstances where maintaining continuous intravenous therapy is difficult or impossible.
- For use in the pre-hospital phase of suspected acute myocardial infarction by a patient who has transmitted his electrocardiogram with a CardioBeeper®, whose electrocardiogram demonstrates the presence of a ventricular arrhythmia and who is instructed by qualified medical personnel to self-administer the LidoPen® Auto-Injector.
Media Articles Related to Lidopen (Lidocaine)
The Death of Joan Rivers: Endoscopy and Anesthesia Risks
Source: MedicineNet Heart Attack Pathology: Photo Essay Specialty [2014.12.09]
Title: The Death of Joan Rivers: Endoscopy and Anesthesia Risks
Category: Doctor's Views
Created: 9/8/2014 12:00:00 AM
Last Editorial Review: 12/9/2014 12:00:00 AM
The ups and downs of the seemingly idle brain
Source: Neurology / Neuroscience News From Medical News Today [2015.01.22]
Even in its quietest moments, the brain is never "off." Instead, while under anesthesia, during slow-wave sleep, or even amid calm wakefulness, the brain's cortex maintains a cycle of activity and...
Published Studies Related to Lidopen (Lidocaine)
Intraoperative systemic lidocaine for pre-emptive analgesics in subtotal
gastrectomy: a prospective, randomized, double-blind, placebo-controlled study. 
lidocaine infusion in patients who underwent subtotal gastrectomy... CONCLUSION: Intravenous lidocaine infusion reduces pain during the postoperative
Efficacy of intraperitoneal and intravenous lidocaine on pain relief after
laparoscopic cholecystectomy. 
infusion for postoperative pain control after laparoscopic cholecystectomy (LC)... CONCLUSIONS: The IP administration of lidocaine and IV lidocaine infusion
Lidocaine/tetracaine peel in topical anesthesia prior to laser-assisted hair
removal: Phase-II and Phase-III study results. 
peel"), which air-dries and can be peeled off 30 min post-application... CONCLUSIONS: After a 30-min application, LT peel was effective and well-tolerated
Reducing the pain of microemulsion propofol injections: a double-blind,
randomized study of three methods of tourniquet and lidocaine. 
of tourniquet application and lidocaine administration on MP injection pain... CONCLUSIONS: We concluded that intravenous retention of lidocaine with the
Higher dose cervical 2% lidocaine gel for IUD insertion: a randomized controlled
for pain during intrauterine device (IUD) insertion... CONCLUSIONS: Two percent lidocaine gel placed on the anterior lip of the cervix
Clinical Trials Related to Lidopen (Lidocaine)
J-Tip® Jet Injection of 1% Buffered Lidocaine or Saline Versus 4% Lidocaine Cream Before Venipuncture or IV Insertion [Not yet recruiting]
To measure and compare pain associated with venipuncture and peripheral intravenous catheter
insertion among pediatric emergency department patients randomized to treatment with one of
three different pain-reduction strategies: J-Tip® jet injection of 1% buffered lidocaine,
J-Tip® jet injection of sterile saline, or application of 4% lidocaine topical cream. The
investigators hypothesize that J-Tip® jet injection of 1% buffered lidocaine will provide
superior local anesthesia compared to saline or lidocaine cream.
Lidocaine and Ketamine in Abdominal Surgery [Recruiting]
This study is being done to determine if combined infusions of lidocaine and ketamine is
better than a lidocaine or ketamine infusion alone, or to placebo in improving recovery
after abdominal hysterectomy. Participants will be randomized into one of four groups.
Evaluations will be done through walking tests, pain and fatigue questionnaires and blood
A Study to Characterize the Phenotype in Patients With Morton's Neuroma and to Explore the Effect of Local Administration of Xylocaine (Lidocaine) [Recruiting]
To characterize the phenotype in patients with Morton's neuroma and to explore the effect of
local administration of Xylocaine (lidocaine)
Intrauterine Lidocaine Infusion for Essure Sterilization Procedures [Recruiting]
The purpose of this study is to assess the level of pain women experience with an Essure
procedure and the effect that lidocaine might have on that pain. We will also assess the
absorption of lidocaine in the uterus by measuring lidocaine levels in the blood.
Comparison of Synera Patch Versus LMX-4 Cream Versus Placebo Patch for Pain Reduction During Venipuncture in Children [Recruiting]
The purpose of this study is to compare the effect of Synera patch versus LMX-4 cream and
placebo on the level of pain, observed distress, difficulty of venipuncture and skin side
effects in children undergoing intravenous blood draw in the emergency setting or the