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Lidocaine and Dextrose (Lidocaine Hydrochloride) - Summary

 


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SUMMARY

Lidocaine Hydrochloride and
5% Dextrose Injection USP

0.4% and 0.8% Lidocaine Hydrochloride and 5% Dextrose Injection, USP are sterile, nonpyrogenic solutions of lidocaine hydrochloride and 5% Dextrose Injection, USP for use in the management of ventricular arrhythmias. Each 100 mL contains lidocaine hydrochloride, anhydrous 400 mg (4 mg/mL) or 800 mg (8 mg/mL) and dextrose hydrous 5 g in water for injection. The osmolarity of the solutions is 282 and 311 mOsmol/liter (calc.) respectively. May contain hydrochloric acid and/or sodium hydroxide for pH adjustment. pH 4.0 (3.0 − 5.5). The solution contains no bacteriostatic, antimicrobial agent or added buffer (except for pH adjustment) and is intended only for use as a single-dose administration. When smaller doses are required, the unused portion should be discarded. Lidocaine administered intravenously is a cardiac antiarrhythmic agent.

Lidocaine Hydrochloride administered intravenously is specifically indicated in the acute management of (1) ventricular arrhythmias occurring during cardiac manipulation, such as cardiac surgery; and (2) life-threatening arrhythmias, particularly those which are ventricular in origin, such as occur during acute myocardial infarction.


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NEWS HIGHLIGHTS RELATED TO LIDOCAINE AND DEXTROSE

Published Studies Related to Lidocaine and Dextrose (Lidocaine)

Lidocaine hydrochloride gel for ocular anesthesia: results of a prospective, randomized study. [2008.09]

The duration of intrathecal bupivacaine mixed with lidocaine. [2008.09]

A randomized clinical trial of lidocaine jelly for prevention of inadvertent retrograde stone migration during pneumatic lithotripsy of ureteral stone. [2008.09]

The effect of intravenous lidocaine on QT changes during tracheal intubation. [2008.09]

I.V. ropivacaine compared with lidocaine for the treatment of tinnitus. [2008.08]

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Clinical Trials Related to Lidocaine and Dextrose (Lidocaine)

Comparison of the Total Dose and Efficacy of Two Lidocaine Concentrations Needed for Cutaneous Surgery Local Anesthesia [Completed]

Preemptive Analgesia for Postlaminectomy [Completed]

Lidocaine Lubricant in Pediatric Urethral Catheterization [Completed]

Efficacy and Safety Study of Lidocaine Vaginal Gel for Recurrent Dysmenorrhea (Painful Periods) [Active, not recruiting]

Lidocaine Supplement for Minimal Invasive Parathyroid Surgery [Completed]

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Page last updated: 2008-11-03

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