Librium Related Published Studies
Well-designed clinical trials related to Librium (Chlordiazepoxide)
A randomized, double-blind comparison of lorazepam and chlordiazepoxide in patients with uncomplicated alcohol withdrawal. [2009.05]
A double-blind randomized placebo-controlled trial of lofexidine in alcohol withdrawal: lofexidine is not a useful adjunct to chlordiazepoxide. [2001.09]
The comparison of the effects of multi and single doses of buspirone, chlordiazepoxide and hydroxyzine on psychomotor function and EEG. [1992]
Transdermal clonidine versus chlordiazepoxide in alcohol withdrawal: a randomized, controlled clinical trial. [1991.03]
Chlordiazepoxide vs. methadone in opiate withdrawal: a preliminary double blind trial. [1989.01]
Double blind study on the efficacy and safety of tetrabamate and chlordiazepoxide in the treatment of the acute alcohol withdrawal syndrome. [1989]
Clonidine versus chlordiazepoxide in acute alcohol withdrawal: a preliminary report. [1988.01]
Well-designed clinical trials possibly related to Librium (Chlordiazepoxide)
Alcohol withdrawal syndrome: symptom-triggered versus fixed-schedule treatment in an outpatient setting. [2011.05]
A prospective, randomized, trial of phenobarbital versus benzodiazepines for acute alcohol withdrawal. [2011.05]
Divalproex sodium (Depakote) for alcohol withdrawal and relapse prevention. [2002]
Interaction between extraversion and drug-induced conditions as indicated by the contingent negative variation. [1994.12]
Individualized treatment for alcohol withdrawal. A randomized double-blind controlled trial. [1994.08.17]
Adinazolam, diazepam, imipramine, and placebo in major depressive disorder: a controlled study. [1991.07]
Other research related to Librium (Chlordiazepoxide)
The discovery of chlordiazepoxide and the clinical introduction of benzodiazepines: half a century of anxiolytic drugs. [2011.05]
Septal co-infusions of glucose with the benzodiazepine agonist chlordiazepoxide impair memory, but co-infusions of glucose with the opiate morphine do not. [2010.03.30]
Buspirone, chlordiazepoxide and diazepam effects in a zebrafish model of anxiety. [2009.11]
The supra-additive hyperactivity caused by an amphetamine-chlordiazepoxide mixture exhibits an inverted-U dose response: negative implications for the use of a model in screening for mood stabilizers. [2009.06]
Psychological stress increases expression of IL-10 and its homolog IL-19 via beta-adrenoceptor activation: reversal by the anxiolytic chlordiazepoxide. [2009.03]
In vitro cytotoxicity study of oxaziridines generated after chlordiazepoxide, demoxepam, and desmethylchlordiazepoxide UV irradiation. [2009]
Acute cross tolerance to midazolam, and not pentobarbital and pregnanolone, after a single dose of chlordiazepoxide in monkeys discriminating midazolam. [2008.12]
Clozapine and olanzapine exhibit an intrinsic anxiolytic property in two conditioned fear paradigms: contrast with haloperidol and chlordiazepoxide. [2008.10]
Effects of chlordiazepoxide on footshock- and corticotropin-releasing factor-induced increases in cortical and hypothalamic norepinephrine secretion in rats. [2008.05]
An evaluation of data for 10 children born to mothers who attempted suicide by taking large doses of alprazolam during pregnancy. [2008.02]
Differential response to gepirone but not to chlordiazepoxide in malnourished rats subjected to learned helplessness. [2008.01]
Effect of restraint stress duration on humoral immune response in albino rats: modulation by chlordiazepoxide. [2008]
Exposure to predator odor stress increases efflux of frontal cortex acetylcholine and monoamines in mice: comparisons with immobilization stress and reversal by chlordiazepoxide. [2006.10.09]
An audit of symptom triggered chlordiazepoxide treatment of alcohol withdrawal on a medical admissions unit. [2005.11]
A comparison of chlordiazepoxide, bretazenil, L838,417 and zolpidem in a validated mouse Vogel conflict test. [2005.11]
Termination of pseudopregnancy in the rat alters the response to progesterone, chlordiazepoxide, and MK-801 in the elevated plus-maze. [2005.07]
Chlordiazepoxide-induced Stevens-Johnson syndrome. [2005.06]
Evidence for PTZ-like cues as a function of time following treatment with chlordiazepoxide: implications for understanding tolerance and withdrawal. [2005.05]
Autoshaping of chlordiazepoxide drinking in non-deprived rats. [2005.02.28]
A population-based case-control study of oral chlordiazepoxide use during pregnancy and risk of congenital abnormalities. [2004.07]
Effects of chlordiazepoxide on extinction and re-acquisition of operant behaviour in mice. [2004.05]
Continuous-infusion flumazenil in the management of chlordiazepoxide toxicity. [2003.11]
Effects of chlordiazepoxide (Librium) during pregnancy and lactation. [2003.05]
Further evidence for the predictive validity of the unstable elevated exposed plus-maze, a behavioural model of extreme anxiety in rats: differential effects of fluoxetine and chlordiazepoxide. [2002.11]
Relation between discriminative and reinforcing effects of midazolam, pentobarbital, chlordiazepoxide, zolpidem, and imidazenil in baboons. [2002.10]
One-trial tolerance to the effects of chlordiazepoxide in the elevated plus-maze is not due to acquisition of a phobic avoidance of open arms during initial exposure. [2002.06.21]
Similar effects of medial supramammillary or systemic injection of chlordiazepoxide on both theta frequency and fixed-interval responding. [2002.03]
The light-enhanced startle paradigm as a putative animal model for anxiety: effects of chlordiazepoxide, flesinoxan and fluvoxamine. [2002.01]
Effects of drug discrimination history on anti-punishment properties of chlordiazepoxide in rats. [2000.11]
Prenatally protein-malnourished rats are less sensitive to the amnestic effects of medial septal infusions of chlordiazepoxide. [2000.09]
Effects of two acute stressors on the anxiolytic efficacy of chlordiazepoxide. [2000.07]
Effects of intraseptal zolpidem and chlordiazepoxide on spatial working memory and high-affinity choline uptake in the hippocampus. [2000.03]
Avoidance of time-out from response-independent food presentation: effects of chlordiazepoxide and buspirone. [1998.10]
The role of subtypes of the opioid receptor in the anxiolytic action of chlordiazepoxide. [1998]
Detection of visual signals by rats: effects of chlordiazepoxide and cholinergic and adrenergic drugs on sustained attention. [1997.12]
Presession noise increases sensitivity to chlordiazepoxide's discriminative stimulus in pigeons. [1997.10]
Effects of chlordiazepoxide, buspirone and cocaine on behavior suppressed by timeout presentation. [1997.06]
Repeated administration of flumazenil does not alter its potency in modifying schedule-controlled behavior in chlordiazepoxide-treated rhesus monkeys. [1997.05]
Anxiety- and activity-related effects of diazepam and chlordiazepoxide in the rat light/dark and dark/light tests. [1997.04]
Chlordiazepoxide improves the performance of septal lesioned but not hippocampal lesioned animals in a Morris maze. [1996.07.01]
[The effect of nifedipine and chlordiazepoxide on alcohol withdrawal syndrome] [1996.03]
Effects of chlordiazepoxide and scopolamine, but not aging, on the detection and identification of conditional visual stimuli. [1995.03]
Treatment of alprazolam withdrawal with chlordiazepoxide substitution and taper. [1994.07]
Crossmodal divided attention in rats: effects of chlordiazepoxide and scopolamine. [1994.06]
Effects of chlordiazepoxide and cocaine on concurrent food and avoidance-of-timeout schedules. [1994.05]
Influence of microwave exposure on chlordiazepoxide effects in the mouse staircase test. [1994.04]
Effect of pentobarbital and chlordiazepoxide on the central pressor action of angiotensins in normo- and hypertensive rats. [1994.02.21]
Effects of intracranial infusions of chlordiazepoxide on spatial learning in the Morris water maze. II. Neuropharmacological specificity. [1993.12.31]
Dissociation constant of chlordiazepoxide in montmorillonite suspension and its pharmaceutical application for a controlled-release dosage form. [1993.09]
Magnesium valproate attenuates hyperactivity induced by dexamphetamine-chlordiazepoxide mixture in rodents. [1993.06.24]
Inhibition of DFMO-induced audiogenic seizures by chlordiazepoxide. [1993]
Development of tolerance to anxiolytic effects of chlordiazepoxide in elevated plus-maze test and decrease of GABAA receptors. [1993]
Clinical experience in the therapy of bites from exotic snakes in Berlin. [1992.11]
Diazepam- and chlordiazepoxide-mediated increases in erythrocyte aldehyde dehydrogenase activity and its possible implications. [1992.05]
Schedule dependence of the interaction of naloxone and chlordiazepoxide. [1992.03]
Assessment of a cholinergic contribution to chlordiazepoxide-induced deficits of place learning in the Morris water maze. [1992.03]
Effects of nitrendipine, chlordiazepoxide, flumazenil and baclofen on the increased anxiety resulting from alcohol withdrawal. [1992.01]
Effects of chlordiazepoxide and beta-carboline 3-carboxylic acid ethyl ester on non-suppressed and minimally-suppressed responding in the squirrel monkey. [1992]
Spinally mediated antinociception following intrathecal chlordiazepoxide--further evidence for a benzodiazepine spinal analgesic effect. [1991.09]
Prenatal oxazepam enhances mouse maternal aggression in the offspring, without modifying acute chlordiazepoxide effects. [1991.01]
Effects of chlordiazepoxide, morphine and amphetamine on responding suppressed by different levels of electric shock in the pigeon are rate dependent. [1991]
Anxiolytic potential of a microgram dose of chlordiazepoxide in the open-field test. [1990.10.23]
Ethological analysis of the effects of MK-801 upon aggressive male mice: similarity to chlordiazepoxide. [1990.09]
Oral administration of chlordiazepoxide plus sodium nitrite investigated for tumor initiating activity in the rat liver. [1990.08]
Evidence that the increased anxiety detected in the elevated plus-maze during chlordiazepoxide withdrawal is not due to enhanced noradrenergic activity. [1989.12]
A liquid diet model of chlordiazepoxide dependence in mice. [1989.12]
Chlordiazepoxide alters intravenous cocaine self-administration in rats. [1989.08]
Chlordiazepoxide and valproate enhancement of saline drinking by nondeprived rats: effects of bicuculline, picrotoxin and Ro15-1788. [1989.06]
Respiratory effects of epidural morphine and sufentanil in the absence and presence of chlordiazepoxide. [1989.04]
Chlordiazepoxide metabolite accumulation in liver disease. [1989.01]
Age and gender effects on chlordiazepoxide kinetics: relation to antipyrine disposition. [1989]
Effects of the acute and chronic administration of chlordiazepoxide on the development of spontaneous motility in chick embryos. [1989]
Toxicity in a case of acute and massive overdose of chlordiazepoxide and its correlation to blood concentration. [1989]
Is substance P a primary afferent neurotransmitter for nociceptive input? III. Valproic acid and chlordiazepoxide decrease behaviors elicited by intrathecal injection of substance P and excitatory compounds. [1988.07.12]
[Effects of chlordiazepoxide on passive avoidance learning in Wistar-Imamichi and F344/Du strain rats] [1987.06]
Effects of delta-9-tetrahydrocannabinol, chlordiazepoxide (Librium), and their combination on pregnancy and offspring in mice [correction of rats]. [1987]
Other possibly related research studies
Benzodiazepines and Risk for Breast Cancer. [2006.01.05]
A selective test for antidepressant treatments using rats bred for stress-induced reduction of motor activity in the swim test. [2005.10]
Different systems in the posterior hypothalamic nucleus of rats control theta frequency and trigger movement. [2005.08.30]
Effects of CRF1 receptor antagonists and benzodiazepines in the Morris water maze and delayed non-matching to position tests. [2005.04]
Evaluation of the effects of lamotrigine, valproate and carbamazepine in a rodent model of mania. [2005.03.07]
Effects of baicalein on beta-amyloid peptide-(25-35)-induced amnesia in mice. [2004.12.03]
[Determination of five components in compound hypotensive tablet by HPLC] [2004.08]
Altered response to benzodiazepine anxiolytics in mice lacking GABA B(1) receptors. [2004.08.16]
The NK1 receptor antagonist NKP608 lacks anxiolytic-like activity in Swiss-Webster mice exposed to the elevated plus-maze. [2004.09.23]
Anxiogenic effect of sleep deprivation in the elevated plus-maze test in mice. [2004.11]
Anxiolytic-like effects of the corticotropin-releasing factor1 (CRF1) antagonist DMP904 [4-(3-pentylamino)-2,7-dimethyl-8-(2-methyl-4-methoxyphenyl)-pyrazolo-[1,5-a]-pyrimidine] administered acutely or chronically at doses occupying central CRF1 receptors in rats. [2004.04]
Elevated startle during withdrawal from acute morphine: a model of opiate withdrawal and anxiety. [2004.01]
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