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Librium (Chlordiazepoxide Hydrochloride) - Published Studies


Librium Related Published Studies

Well-designed clinical trials related to Librium (Chlordiazepoxide)

A double blind randomised comparison of chlordiazepoxide and lorazepam in alcohol withdrawal. [2013]

Gabapentin versus chlordiazepoxide for outpatient alcohol detoxification treatment. [2013]

A randomized, double-blind comparison of lorazepam and chlordiazepoxide in patients with uncomplicated alcohol withdrawal. [2009.05]

A double-blind randomized placebo-controlled trial of lofexidine in alcohol withdrawal: lofexidine is not a useful adjunct to chlordiazepoxide. [2001.09]

The comparison of the effects of multi and single doses of buspirone, chlordiazepoxide and hydroxyzine on psychomotor function and EEG. [1992]

Transdermal clonidine versus chlordiazepoxide in alcohol withdrawal: a randomized, controlled clinical trial. [1991.03]

Chlordiazepoxide vs. methadone in opiate withdrawal: a preliminary double blind trial. [1989.01]

Double blind study on the efficacy and safety of tetrabamate and chlordiazepoxide in the treatment of the acute alcohol withdrawal syndrome. [1989]

Clonidine versus chlordiazepoxide in acute alcohol withdrawal: a preliminary report. [1988.01]

Well-designed clinical trials possibly related to Librium (Chlordiazepoxide)

Alcohol withdrawal syndrome: symptom-triggered versus fixed-schedule treatment in an outpatient setting. [2011.05]

A prospective, randomized, trial of phenobarbital versus benzodiazepines for acute alcohol withdrawal. [2011.05]

Divalproex sodium (Depakote) for alcohol withdrawal and relapse prevention. [2002]

Interaction between extraversion and drug-induced conditions as indicated by the contingent negative variation. [1994.12]

Individualized treatment for alcohol withdrawal. A randomized double-blind controlled trial. [1994.08.17]

Adinazolam, diazepam, imipramine, and placebo in major depressive disorder: a controlled study. [1991.07]

Other research related to Librium (Chlordiazepoxide)

Cost-effectiveness analysis of baclofen and chlordiazepoxide in uncomplicated alcohol-withdrawal syndrome. [2014]

The discovery of chlordiazepoxide and the clinical introduction of benzodiazepines: half a century of anxiolytic drugs. [2011.05]

Septal co-infusions of glucose with the benzodiazepine agonist chlordiazepoxide impair memory, but co-infusions of glucose with the opiate morphine do not. [2010.03.30]

Buspirone, chlordiazepoxide and diazepam effects in a zebrafish model of anxiety. [2009.11]

The supra-additive hyperactivity caused by an amphetamine-chlordiazepoxide mixture exhibits an inverted-U dose response: negative implications for the use of a model in screening for mood stabilizers. [2009.06]

Psychological stress increases expression of IL-10 and its homolog IL-19 via beta-adrenoceptor activation: reversal by the anxiolytic chlordiazepoxide. [2009.03]

In vitro cytotoxicity study of oxaziridines generated after chlordiazepoxide, demoxepam, and desmethylchlordiazepoxide UV irradiation. [2009]

Acute cross tolerance to midazolam, and not pentobarbital and pregnanolone, after a single dose of chlordiazepoxide in monkeys discriminating midazolam. [2008.12]

Clozapine and olanzapine exhibit an intrinsic anxiolytic property in two conditioned fear paradigms: contrast with haloperidol and chlordiazepoxide. [2008.10]

Effects of chlordiazepoxide on footshock- and corticotropin-releasing factor-induced increases in cortical and hypothalamic norepinephrine secretion in rats. [2008.05]

An evaluation of data for 10 children born to mothers who attempted suicide by taking large doses of alprazolam during pregnancy. [2008.02]

Differential response to gepirone but not to chlordiazepoxide in malnourished rats subjected to learned helplessness. [2008.01]

Effect of restraint stress duration on humoral immune response in albino rats: modulation by chlordiazepoxide. [2008]

Exposure to predator odor stress increases efflux of frontal cortex acetylcholine and monoamines in mice: comparisons with immobilization stress and reversal by chlordiazepoxide. [2006.10.09]

An audit of symptom triggered chlordiazepoxide treatment of alcohol withdrawal on a medical admissions unit. [2005.11]

A comparison of chlordiazepoxide, bretazenil, L838,417 and zolpidem in a validated mouse Vogel conflict test. [2005.11]

Termination of pseudopregnancy in the rat alters the response to progesterone, chlordiazepoxide, and MK-801 in the elevated plus-maze. [2005.07]

Chlordiazepoxide-induced Stevens-Johnson syndrome. [2005.06]

Evidence for PTZ-like cues as a function of time following treatment with chlordiazepoxide: implications for understanding tolerance and withdrawal. [2005.05]

Autoshaping of chlordiazepoxide drinking in non-deprived rats. [2005.02.28]

A population-based case-control study of oral chlordiazepoxide use during pregnancy and risk of congenital abnormalities. [2004.07]

Effects of chlordiazepoxide on extinction and re-acquisition of operant behaviour in mice. [2004.05]

Continuous-infusion flumazenil in the management of chlordiazepoxide toxicity. [2003.11]

Effects of chlordiazepoxide (Librium) during pregnancy and lactation. [2003.05]

Further evidence for the predictive validity of the unstable elevated exposed plus-maze, a behavioural model of extreme anxiety in rats: differential effects of fluoxetine and chlordiazepoxide. [2002.11]

Relation between discriminative and reinforcing effects of midazolam, pentobarbital, chlordiazepoxide, zolpidem, and imidazenil in baboons. [2002.10]

One-trial tolerance to the effects of chlordiazepoxide in the elevated plus-maze is not due to acquisition of a phobic avoidance of open arms during initial exposure. [2002.06.21]

Similar effects of medial supramammillary or systemic injection of chlordiazepoxide on both theta frequency and fixed-interval responding. [2002.03]

The light-enhanced startle paradigm as a putative animal model for anxiety: effects of chlordiazepoxide, flesinoxan and fluvoxamine. [2002.01]

Effects of drug discrimination history on anti-punishment properties of chlordiazepoxide in rats. [2000.11]

Prenatally protein-malnourished rats are less sensitive to the amnestic effects of medial septal infusions of chlordiazepoxide. [2000.09]

Effects of two acute stressors on the anxiolytic efficacy of chlordiazepoxide. [2000.07]

Effects of intraseptal zolpidem and chlordiazepoxide on spatial working memory and high-affinity choline uptake in the hippocampus. [2000.03]

Avoidance of time-out from response-independent food presentation: effects of chlordiazepoxide and buspirone. [1998.10]

The role of subtypes of the opioid receptor in the anxiolytic action of chlordiazepoxide. [1998]

Detection of visual signals by rats: effects of chlordiazepoxide and cholinergic and adrenergic drugs on sustained attention. [1997.12]

Presession noise increases sensitivity to chlordiazepoxide's discriminative stimulus in pigeons. [1997.10]

Effects of chlordiazepoxide, buspirone and cocaine on behavior suppressed by timeout presentation. [1997.06]

Repeated administration of flumazenil does not alter its potency in modifying schedule-controlled behavior in chlordiazepoxide-treated rhesus monkeys. [1997.05]

Anxiety- and activity-related effects of diazepam and chlordiazepoxide in the rat light/dark and dark/light tests. [1997.04]

Chlordiazepoxide improves the performance of septal lesioned but not hippocampal lesioned animals in a Morris maze. [1996.07.01]

[The effect of nifedipine and chlordiazepoxide on alcohol withdrawal syndrome] [1996.03]

Effects of chlordiazepoxide and scopolamine, but not aging, on the detection and identification of conditional visual stimuli. [1995.03]

Treatment of alprazolam withdrawal with chlordiazepoxide substitution and taper. [1994.07]

Crossmodal divided attention in rats: effects of chlordiazepoxide and scopolamine. [1994.06]

Effects of chlordiazepoxide and cocaine on concurrent food and avoidance-of-timeout schedules. [1994.05]

Influence of microwave exposure on chlordiazepoxide effects in the mouse staircase test. [1994.04]

Effect of pentobarbital and chlordiazepoxide on the central pressor action of angiotensins in normo- and hypertensive rats. [1994.02.21]

Effects of intracranial infusions of chlordiazepoxide on spatial learning in the Morris water maze. II. Neuropharmacological specificity. [1993.12.31]

Dissociation constant of chlordiazepoxide in montmorillonite suspension and its pharmaceutical application for a controlled-release dosage form. [1993.09]

Magnesium valproate attenuates hyperactivity induced by dexamphetamine-chlordiazepoxide mixture in rodents. [1993.06.24]

Inhibition of DFMO-induced audiogenic seizures by chlordiazepoxide. [1993]

Development of tolerance to anxiolytic effects of chlordiazepoxide in elevated plus-maze test and decrease of GABAA receptors. [1993]

Clinical experience in the therapy of bites from exotic snakes in Berlin. [1992.11]

Diazepam- and chlordiazepoxide-mediated increases in erythrocyte aldehyde dehydrogenase activity and its possible implications. [1992.05]

Schedule dependence of the interaction of naloxone and chlordiazepoxide. [1992.03]

Assessment of a cholinergic contribution to chlordiazepoxide-induced deficits of place learning in the Morris water maze. [1992.03]

Effects of nitrendipine, chlordiazepoxide, flumazenil and baclofen on the increased anxiety resulting from alcohol withdrawal. [1992.01]

Effects of chlordiazepoxide and beta-carboline 3-carboxylic acid ethyl ester on non-suppressed and minimally-suppressed responding in the squirrel monkey. [1992]

Spinally mediated antinociception following intrathecal chlordiazepoxide--further evidence for a benzodiazepine spinal analgesic effect. [1991.09]

Prenatal oxazepam enhances mouse maternal aggression in the offspring, without modifying acute chlordiazepoxide effects. [1991.01]

Effects of chlordiazepoxide, morphine and amphetamine on responding suppressed by different levels of electric shock in the pigeon are rate dependent. [1991]

Anxiolytic potential of a microgram dose of chlordiazepoxide in the open-field test. [1990.10.23]

Ethological analysis of the effects of MK-801 upon aggressive male mice: similarity to chlordiazepoxide. [1990.09]

Oral administration of chlordiazepoxide plus sodium nitrite investigated for tumor initiating activity in the rat liver. [1990.08]

Evidence that the increased anxiety detected in the elevated plus-maze during chlordiazepoxide withdrawal is not due to enhanced noradrenergic activity. [1989.12]

A liquid diet model of chlordiazepoxide dependence in mice. [1989.12]

Chlordiazepoxide alters intravenous cocaine self-administration in rats. [1989.08]

Chlordiazepoxide and valproate enhancement of saline drinking by nondeprived rats: effects of bicuculline, picrotoxin and Ro15-1788. [1989.06]

Respiratory effects of epidural morphine and sufentanil in the absence and presence of chlordiazepoxide. [1989.04]

Chlordiazepoxide metabolite accumulation in liver disease. [1989.01]

Age and gender effects on chlordiazepoxide kinetics: relation to antipyrine disposition. [1989]

Effects of the acute and chronic administration of chlordiazepoxide on the development of spontaneous motility in chick embryos. [1989]

Toxicity in a case of acute and massive overdose of chlordiazepoxide and its correlation to blood concentration. [1989]

Is substance P a primary afferent neurotransmitter for nociceptive input? III. Valproic acid and chlordiazepoxide decrease behaviors elicited by intrathecal injection of substance P and excitatory compounds. [1988.07.12]

[Effects of chlordiazepoxide on passive avoidance learning in Wistar-Imamichi and F344/Du strain rats] [1987.06]

Effects of delta-9-tetrahydrocannabinol, chlordiazepoxide (Librium), and their combination on pregnancy and offspring in mice [correction of rats]. [1987]

Other possibly related research studies

Benzodiazepines and Risk for Breast Cancer. [2006.01.05]

A selective test for antidepressant treatments using rats bred for stress-induced reduction of motor activity in the swim test. [2005.10]

Different systems in the posterior hypothalamic nucleus of rats control theta frequency and trigger movement. [2005.08.30]

Effects of CRF1 receptor antagonists and benzodiazepines in the Morris water maze and delayed non-matching to position tests. [2005.04]

Evaluation of the effects of lamotrigine, valproate and carbamazepine in a rodent model of mania. [2005.03.07]

Effects of baicalein on beta-amyloid peptide-(25-35)-induced amnesia in mice. [2004.12.03]

[Determination of five components in compound hypotensive tablet by HPLC] [2004.08]

Altered response to benzodiazepine anxiolytics in mice lacking GABA B(1) receptors. [2004.08.16]

The NK1 receptor antagonist NKP608 lacks anxiolytic-like activity in Swiss-Webster mice exposed to the elevated plus-maze. [2004.09.23]

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