Levothroid (Levothyroxine Sodium) - Summary

LEVOTHROID SUMMARY

LEVOTHROID^® (levothyroxine sodium tablets, USP) contains synthetic crystalline L-3,3',5,5'-tetraiodothyronine sodium salt [levothyroxine (T₄) sodium]. Synthetic T₄ is identical to that produced in the human thyroid gland.

Levothyroxine sodium is used for the following indications:

Hypothyroidism - As replacement or supplemental therapy in congenital or acquired hypothyroidism of any etiology, except transient hypothyroidism during the recovery phase of subacute thyroiditis. Specific indications include: primary (thyroidal), secondary (pituitary), and tertiary (hypothalamic) hypothyroidism and subclinical hypothyroidism. Primary hypothyroidism may result from functional deficiency, primary atrophy, partial or total congenital absence of the thyroid gland, or from the effects of surgery, radiation, or drugs, with or without the presence of goiter.

Pituitary TSH Suppression - In the treatment or prevention of various types of euthyroid goiters (see WARNINGS and PRECAUTIONS), including thyroid nodules (see WARNINGS and PRECAUTIONS), subacute or chronic lymphocytic thyroiditis (Hashimoto's thyroiditis), multinodular goiter (see WARNINGS and PRECAUTIONS) and, as an adjunct to surgery and radioiodine therapy in the management of thyrotropin-dependent well-differentiated thyroid cancer.

See all Levothroid indications & dosage >>

LEVOTHROID NEWS HIGHLIGHTS

Media Articles Related to Levothroid (Levothyroxine)

levothyroxine sodium, Synthroid, Levoxyl, Levothroid, Unithroid
Source: MedicineNet Hypothyroidism During Pregnancy Specialty [2007.11.16]

more >>

Published Studies Related to Levothroid (Levothyroxine)

Lipid profile in different degrees of hypothyroidism and effects of levothyroxine replacement in mild thyroid failure. [2008.04]

Levothyroxine in euthyroid autoimmune thyroiditis and type 1 diabetes: a randomized, controlled trial. [2007.05]

Levothyroxine in euthyroid autoimmune thyroiditis and type 1 diabetes: a randomised, controlled trial. [2007.02.13]

Comparative bioavailability of different formulations of levothyroxine and liothyronine in healthy volunteers. [2006.12]

A bioequivalence study of levothyroxine tablets versus an oral levothyroxine solution in healthy volunteers. [2006.04]

more >>

Clinical Trials Related to Levothroid (Levothyroxine)

Fasting Study of Levothyroxine Sodium Tablets 300 μg to Levothroid® Tablets 300 μg [Completed]

Fasting Study of Levothyroxine Sodium Tablets 200 mg to Synthroid Tablets 200 mg [Completed]

Fasting Study of Levothyroxine Sodium Tablets 300 μg to Synthroid® Tablets 300 μg [Completed]

Fasting Study of Levothyroxine Sodium Tablets 300 Mcg to Synthroid® Tablets 300 Mcg [Completed]

Phase 4 Study in Secondary Hypothyroidism: Body Weight Adapted Thyroxin Treatment and Triiodothyronine Supplementation [Completed]

more >>

LEVOTHROID PATIENT REVIEWS / RATINGS / COMMENTS

Levothroid review by 46 year old female patient
		Rating
Overall rating:
Effectiveness:		Considerably Effective
Side effects:		No Side Effects
		Treatment Info
Condition / reason:		hypothyroidism
Dosage & duration:		.88mg taken once daily for the period of still take it
Other conditions:		none
Other drugs taken:		none
		Reported Results
Benefits:		I had felt very tired all the time before I started taking the medication. Also my skin and hair seemed to be very dry. I have noticed a significant improvement in my energy level since taking the medication. Also my skin and hair have both improved over time.
Side effects:		I didn't have any side effects that I could associate with taking the medication.
Comments:		I take the medication first thing in the morning about 30 minutes to an hour before I eat breakfast.

Levothroid review by 55 year old female patient
		Rating
Overall rating:
Effectiveness:		Highly Effective
Side effects:		No Side Effects
		Treatment Info
Condition / reason:		thyroid
Dosage & duration:		.1mg taken daily for the period of 20+ years
Other conditions:		n/a
Other drugs taken:		n/a
		Reported Results
Benefits:		balancing of thyroid back to normal range. Prior to treatment, patient had some mental confusion, weight gain, needed extreme amounts of sleep. With treatment, mental acuity was obtained, weight stablized, energy increased. At one time treatment was discontinued for one month by MD to ensure that the thyroid gland was not producing adequate amounts of thyroid. Patient was put back on treatment after blood tests confirmed levels in bloodstream. This treatment has made a positive difference in patients life.
Side effects:		n/a
Comments:		.1mg daily orally.

Levothroid review by 55 year old female patient
		Rating
Overall rating:
Effectiveness:		Highly Effective
Side effects:		No Side Effects
		Treatment Info
Condition / reason:		thyroid
Dosage & duration:		.1mg taken daily for the period of 20+ years
Other conditions:		n/a
Other drugs taken:		n/a
		Reported Results
Benefits:		balancing of thyroid back to normal range. Prior to treatment, patient had some mental confusion, weight gain, needed extreme amounts of sleep. With treatment, mental acuity was obtained, weight stablized, energy increased. At one time treatment was discontinued for one month by MD to ensure that the thyroid gland was not producing adequate amounts of thyroid. Patient was put back on treatment after blood tests confirmed levels in bloodstream. This treatment has made a positive difference in patients life.
Side effects:		n/a
Comments:		.1mg daily orally.