LEVORPHANOL SUMMARY
Levorphanol tartrate is a potent opioid analgesic with a molecular formula of C17H23NO • C4H6O6• 2H2O and molecular weight 443.
Levorphanol tartrate tablets are indicated for the management of moderate to severe pain where an opioid analgesic is appropriate.
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NEWS HIGHLIGHTS
Clinical Trials Related to Levorphanol
Evolution of Analgesic Tolerance With Opioids [Completed]
The purpose of this study is to determine the extent to which analgesic tolerance develops
in chronic pain patients who are either started on opioids or who receive an increase in
pre-study opioid dose level and then observed during long-term (20 weeks) stable opioid
therapy. In addition to clinical measures of relief of ongoing chronic pain, estimation of
tolerance development will be supplemented by periodic assessment of the anti-nociceptive
effects of opioids using the brief thermal sensitization model.
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Page last updated: 2011-07-25
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