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Levo-Dromoran (Levorphanol Tartrate) - Published Studies

 


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Levo-Dromoran Related Published Studies

Well-designed clinical trials possibly related to Levo-Dromoran (Levorphanol)

Efficacy of pre- and postoperative oral dextromethorphan for reduction of intra- and 24-hour postoperative morphine consumption for transabdominal hysterectomy. [2007.07]

Preoperative oral dextromethorphan vs. clonidine to prevent tourniquet-induced cardiovascular responses in orthopaedic patients under general anaesthesia. [2007.06]

A phase III randomized, double-blind, placebo-controlled study evaluating dextromethorphan plus slow-release morphine for chronic cancer pain relief in terminally ill patients. [2007.04]

Efficacy of a single evening dose of syrup containing paracetamol, dextromethorphan hydrobromide, doxylamine succinate and ephedrine sulfate in subjects with multiple common cold symptoms. [2007.04]

Simultaneous determination of dextromethorphan, dextrorphan, and guaifenesin in human plasma using semi-automated liquid/liquid extraction and gradient liquid chromatography tandem mass spectrometry. [2007.01.17]

Placebo-controlled comparison of a morphine/dextromethorphan combination with morphine on experimental pain and hyperalgesia in healthy volunteers. [2007.01]

Dextromethorphan premedication reduces midazolam requirement: objective and subjective parameters in peribronchoscopy. [2007]

Preoperative cotreatment with dextromethorphan and ketorolac provides an enhancement of pain relief after laparoscopic-assisted vaginal hysterectomy. [2006.11]

Dextromethorphan premedication reduced postoperative analgesic consumption in patients after oral surgery. [2006.11]

Dextromethorphan and quinidine in adult patients with uncontrolled painful diabetic peripheral neuropathy: a 29-day, multicenter, open-label, dose-escalation study. [2006.10]

Child assessment of dextromethorphan, diphenhydramine, and placebo for nocturnal cough due to upper respiratory infection. [2006.09]

Comparative bioavailability of the microemulsion formulation of cyclosporine (Neoral) with a generic dispersion formulation (Cicloral) in young healthy male volunteers. [2006.06]

Randomized, controlled trial of dextromethorphan/quinidine for pseudobulbar affect in multiple sclerosis. [2006.05]

Absolute oral bioavailability of traxoprodil in cytochrome P450 2D6 extensive and poor metabolisers. [2006]

Effect of a triphasic oral contraceptive on drug-metabolizing enzyme activity as measured by the validated cooperstown 5+1 cocktail. [2005.12]

QT and QTc interval with standard and supratherapeutic doses of darifenacin, a muscarinic M3 selective receptor antagonist for the treatment of overactive bladder. [2005.09]

MorphiDex (morphine sulfate/dextromethorphan hydrobromide combination) in the treatment of chronic pain: three multicenter, randomized, double-blind, controlled clinical trials fail to demonstrate enhanced opioid analgesia or reduction in tolerance. [2005.06]

Inhibition of CYP2D6 activity by bupropion. [2005.06]

Preincisional dextromethorphan combined with thoracic epidural anesthesia and analgesia improves postoperative pain and bowel function in patients undergoing colonic surgery. [2005.05]

The interaction effect of perioperative cotreatment with dextromethorphan and intravenous lidocaine on pain relief and recovery of bowel function after laparoscopic cholecystectomy. [2005.02]

Intravenous dextromethorphan to human volunteers: relationship between pharmacokinetics and anti-hyperalgesic effect. [2005.02]

Other research related to Levo-Dromoran (Levorphanol)

Can levorphanol be used like methadone for intractable refractory pain? [2007.04]

Levorphanol: the forgotten opioid. [2007.03]

Other possibly related research studies

Dextromethorphan/quinidine: a novel dextromethorphan product for the treatment of emotional lability. [2006.12]

Dextromethorphan abuse in adolescence: an increasing trend: 1999-2004. [2006.12]

3-Hydroxymorphinan, a metabolite of dextromethorphan, protects nigrostriatal pathway against MPTP-elicited damage both in vivo and in vitro. [2006.12]

Effect of diet on the development of drug metabolism by cytochrome P-450 enzymes in healthy infants. [2006.12]

[Dextromethorphan enhances analgesic activity of propacetamol--experimental study] [2005]

Additive effect of dextromethorphan on the inhibitory effect of anti-NT4 on morphine tolerance. [2006]

Dextromethorphan protects male but not female mice with brain ischemia. [2006.08.21]

Potential interactions of methylphenidate and atomoxetine with dextromethorphan. [2006.07]

Dextromethorphan abuse in Thai adolescents: A report of two cases and review of literature. [2005.11]

Modeling film-coat non-uniformity in polymer coated pellets: a stochastic approach. [2006.10.12]

The intravenous ketamine test predicts subsequent response to an oral dextromethorphan treatment regimen in fibromyalgia patients. [2006.06]

Pseudobulbar affect in multiple sclerosis: toward the development of innovative therapeutic strategies. [2006.06.15]

Chronic addiction to dextromethorphan cough syrup: a case report. [2006.05]

Evaluation of the drug interaction potential of aplaviroc, a novel human immunodeficiency virus entry inhibitor, using a modified cooperstown 5 + 1 cocktail. [2006.05]

CYP2D6 genotype and phenotype in Amerindians of Tepehuano origin and Mestizos of Durango, Mexico. [2006.05]

Preparation and in vitro release of dual-drug resinates containing equivalent content dextromethorphan and diphenhydramine. [2006.04]

Efficacy, abuse, and toxicity of over-the-counter cough and cold medicines in the pediatric population. [2006.04]

Alterations of postsynaptic density proteins in the hippocampus of rat offspring from the morphine-addicted mother: Beneficial effect of dextromethorphan. [2006]

Effects of dextrorotatory morphinans on alpha3beta4 nicotinic acetylcholine receptors expressed in Xenopus oocytes. [2006.04.24]

Ovariectomy ameliorates dextromethorphan--induced memory impairment in young female rats. [2006.01]

A qualitative systematic review of peri-operative dextromethorphan in post-operative pain. [2006.01]

Phenotypical expression of CYP2D6 in amerindians of tepehuano origin from Durango, Mexico. [2005]

Repetitive dextromethorphan at adolescence affects water maze learning in female rats. [2006.02]

Review of pseudobulbar affect including a novel and potential therapy. [2005.09]

Effects of steady-state lasofoxifene on CYP2D6- and CYP2E1-mediated metabolism. [2006.01]

Effect of low-dose ritonavir (100 mg twice daily) on the activity of cytochrome P450 2D6 in healthy volunteers. [2005.12]

Measurement of CYP2D6 and CYP3A4 activity in vivo with dextromethorphan: sources of variability and predictors of adverse effects in 419 healthy subjects. [2005.12]

The effect of CYP2D6 polymorphisms on dextromethorphan metabolism in Mexican Americans. [2005.11]

Adolescent abuse of dextromethorphan. [2005.09]

The treatment of the behavioral sequelae of autism with dextromethorphan: a case report. [2005.08]

Side effects of dextromethorphan abuse, a case series. [2005.09]

A study of the effects of lorazepam and dextromethorphan on the response to cortical 1 Hz repetitive transcranial magnetic stimulation. [2005.09.08]

Dextromethorphan-induced delirium and possible methadone interaction. [2005.03]

Effects of the competitive N-methyl-D-aspartate receptor antagonist, LY235959 [(-)-6-phosphonomethyl-deca-hydroisoquinoline-3-carboxylic acid], on responding for cocaine under both fixed and progressive ratio schedules of reinforcement. [2005.10]

Effects of the N-methyl-D-aspartate receptor antagonist dextromethorphan on temporal summation of pain are similar in fibromyalgia patients and normal control subjects. [2005.05]

Is antagonism of alpha3beta4 nicotinic receptors a strategy to reduce morphine dependence? [2005.04.25]

Dextromethorphan to dextrorphan urinary metabolic ratio does not reflect dextromethorphan oral clearance. [2005.07]

Femtomolar concentrations of dextromethorphan protect mesencephalic dopaminergic neurons from inflammatory damage. [2005.04]

The dextromethorphan analog dimemorfan attenuates kainate-induced seizures via sigma1 receptor activation: comparison with the effects of dextromethorphan. [2005.04]

Dextromethorphan metabolic phenotyping in an Iranian population. [2005.02]

Protective effect of dextromethorphan against endotoxic shock in mice. [2005.01.15]

[Fundamentals of modern treatment of myopia] [2005]

Over-the-counter cold medications-postmortem findings in infants and the relationship to cause of death. [2005.10]

Possible role of pseudoephedrine and other over-the-counter cold medications in the deaths of very young children. [2007.03]

Identification of critical residues in novel drug metabolizing mutants of cytochrome P450 BM3 using random mutagenesis. [2007.02.08]

Reboxetine and cytochrome P450--comparison with paroxetine treatment in humans. [2007.01]

Incorporating in vitro information on drug metabolism into clinical trial simulations to assess the effect of CYP2D6 polymorphism on pharmacokinetics and pharmacodynamics: dextromethorphan as a model application. [2007.02]

Mesenteric artery clamping/unclamping-induced acute lung injury is attenuated by N-methyl-D-aspartate antagonist dextromethorphan. [2006.11]

Beneficial effects of LK-4, an analog of dextromethorphan on lipopolysaccharide-induced sepsis in rats. [2006.11]

Drug release properties of polymer coated ion-exchange resin complexes: experimental and theoretical evaluation. [2007.03]

Dextromethorphan or dextrorphan have a local anesthetic effect on infiltrative cutaneous analgesia in rats. [2007.05]

A placebo double-blind pilot study of dextromethorphan for problematic behaviors in children with autism. [2007.01]

Impairments in water maze learning of aged rats that received dextromethorphan repeatedly during adolescent period. [2007.03]

Potential interactions of methylphenidate and atomoxetine with dextromethorphan. [2006.07]

"Crystal dex:" free-base dextromethorphan. [2007.05]

Dextromethorphan: a review of N-methyl-d-aspartate receptor antagonist in the management of pain. [2007.03]

Post-treatment of dextromethorphan reverses morphine effect on conditioned place preference in rats. [2007.06]

Effect of honey on CYP3A4, CYP2D6 and CYP2C19 enzyme activity in healthy human volunteers. [2007.04]

Dextromethorphan-induced near-fatal suicide attempt in a slow metabolizer at cytochrome P450 2D6. [2007.06]

"Pharming": the abuse of prescription and over-the-counter drugs in teens. [2007.06]

Therapeutic use of dextromethorphan: key learnings from treatment of pseudobulbar affect. [2007.08.15]

Involuntary emotional expression disorder: treating the untreated. [2007.04]

Effects of dextrorotatory morphinans on brain Na+ channels expressed in Xenopus oocytes. [2007.06.14]

Modulating drug release and matrix erosion of alginate matrix capsules by microenvironmental interaction with calcium ion. [2007.08]

Effects of environmental enrichment on sensitivity to mu, kappa, and mixed-action opioids in female rats. [2008.07.05]

Effectiveness of opioids in the treatment of chronic non-cancer pain. [2008.03]

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