Levemir (Insulin Detemir Subcutaneous) - Summary

LEVEMIR SUMMARY

LEVEMIR^®(insulin detemir [rDNA origin] injection)

LEVEMIR^® (insulin detemir [rDNA origin] injection) is a sterile solution of insulin detemir for use as an injection. Insulin detemir is a long-acting basal insulin analog, with up to 24 hours duration of action, produced by a process that includes expression of recombinant DNA in Saccharomyces cerevisiae followed by chemical modification. Insulin detemir differs from human insulin in that the amino acid threonine in position B30 has been omitted, and a C14 fatty acid chain has been attached to the amino acid B29.

LEVEMIR is indicated for once- or twice-daily subcutaneous administration for the treatment of adult and pediatric patients with type 1 diabetes mellitus or adult patients with type 2 diabetes mellitus who require basal (long acting) insulin for the control of hyperglycemia.

LEVEMIR NEWS HIGHLIGHTS

Published Studies Related to Levemir (Insulin Detemir Subcutaneous)

Comparison of insulin analogue regimens in people with type 2 diabetes mellitus in the PREFER Study: a randomized controlled trial. [2008.07.17]

Long-term efficacy and safety of insulin detemir compared to Neutral Protamine Hagedorn insulin in patients with Type 1 diabetes using a treat-to-target basal-bolus regimen with insulin aspart at meals: a 2-year, randomized, controlled trial. [2008.04]

A randomised, 52-week, treat-to-target trial comparing insulin detemir with insulin glargine when administered as add-on to glucose-lowering drugs in insulin-naive people with type 2 diabetes. [2008.03]

Different brain responses to hypoglycemia induced by equipotent doses of the long-acting insulin analog detemir and human regular insulin in humans. [2008.03]

Improving glycemic control with insulin detemir using the 303 Algorithm in insulin naive patients with type 2 diabetes: a subgroup analysis of the US PREDICTIVE 303 study. [2008.01]

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Clinical Trials Related to Levemir (Insulin Detemir Subcutaneous)

Observational Study on Treatment Satisfaction of Levemir® Versus Protaphane® During "Real-Life" Usage in Germany [Recruiting]

Observational Study of Safety and Tolerability of Levemirâ„¢ FlexPenâ„¢ (Insulin Detemir) in the Treatment of Type 1 and Type 2 Diabetes Mellitus [Recruiting]

Observational Study of Glycaemic Control in Patients Uncontrolled on Oral Antidiabetic Agents and Starting With 1 (Once) Daily Levemir® (Insulin Detemir) as the Treatment of Type 2 Diabetes Mellitus [Recruiting]

Observational Study on the Weight Effect of Insulin Detemir (Levemir®) in Type 2 Diabetics [Recruiting]

Observational Safety Study in Subjects Using Levemir® (Insulin Detemir) for the Treatment of Type 2 Diabetes Mellitus [Recruiting]

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