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Leukine (Sargramostim) - Current Clinical Trials

 


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Leukine Related Clinical Trials

Randomized Phase 2 Trial of Pre-Chemotherapy Leukine Vs. Leukine-Dexamethasone in Combination With Gemzar & 5-FU in Patients With Metastatic Renal Cell Carcinoma [Withdrawn]

Immuno-Augmentation With GM-CSF of Pneumococcal Vaccine in Chronic Lymphocytic Leukemia Patients [Active, not recruiting]

GM-CSF as Adjuvant Therapy of Melanoma [Completed]

Randomized Phase III Trial of Leukine® Vs Neupogen® in Patients Receiving Cisplatin & Gemcitabine for Urothelial Cancer [Terminated]

Open-Label Trial of LEUKINE® in Active Crohn's Disease [Completed]

Phase I Trial of mBACOD and Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) in AIDS-Associated Large Cell, Immunoblastic, and Small Non-Cleaved Lymphoma [Completed]

Efficacy Study of Sargramostim in the Retreatment of Patients Who Have Crohn’s Disease Who Have Previously Responded to Treatment With Sargramostim [Completed]

Injection Of AJCC Stage IIB, IIC, III And IV Melanoma Patients With A Multi-Epitope Peptide Vaccine Using GM-CSF DNA As An Adjuvant: A Pilot Trial To Assess Safety And Immunity [Active, not recruiting]

Open-Label of LEUKINE® in Active Crohn's Disease [Terminated]

A Phase II Trial of Docetaxel/Prednisone in Combination With Sargramostim as Treatment for Hormone-Refractory Prostate Cancer [Active, not recruiting]

A Phase I Trial of Recombinant Human Granulocyte-Macrophage Colony Stimulating Factor (rHuGM-CSF), Recombinant Alpha Interferon and Azidothymidine (AZT) in AIDS-Associated Kaposi's Sarcoma

Vaccine Therapy and Sargramostim Compared With Placebo and Sargramostim Following Rituximab in Treating Patients With Non-Hodgkin's Lymphoma [Active, not recruiting]

Study of Sargramostim in Moderately to Severely Active Crohn’s Disease [Terminated]

Phase II Trial of Rituximab Plus Sargramostim for Newly Diagnosed Follicular B-Cell Lymphoma in Adults [Recruiting]

Combination Chemotherapy, Radiation Therapy, and Sargramostim Before and After Surgery in Treating Patients With Soft Tissue Sarcoma That Can Be Removed By Surgery [Active, not recruiting]

Study of Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) for Patients With Rising Prostate-Specific Antigen (PSA) [Active, not recruiting]

Fludarabine, Cyclophosphamide, and Rituximab (FCR) Plus Sargramostim (GM-CSF) as Frontline Therapy for Symptomatic Chronic Lymphocytic Leukemia [Recruiting]

Sargramostim in Reducing Graft-Versus-Host Disease in Patients Who Are Undergoing Donor Stem Cell Transplantation for Hematologic Cancer or Aplastic Anemia [Completed]

Docetaxel Followed By GM-CSF in Treating Patients With Metastatic Prostate Cancer That Did Not Respond to Previous Hormone Therapy [Recruiting]

A Prospective, Randomized, Phase III Trial of FLAC (5-Fluorouracil, Leucovorin, Adriamycin, Cytoxan) Chemotherapy With GM-CSF (Granulocyte-Macrophage Colony-Stimulating Factor) Versus PIXY 321 in Advanced Breast Cancer [Completed]

Sargramostim After Bone Marrow Transplantation in Treating Patients With Myelodysplastic Syndrome [Completed]

Vaccine Therapy Plus Sargramostim and Chemotherapy in Treating Women With Stage II or Stage III Breast Cancer [Completed]

A Multicenter, Randomized, Placebo-Controlled, Double-Blinded, Phase I Trial to Evaluate the Safety and Immunogenicity of Live Recombinant Canarypox ALVAC-HIV vCP205 Combined With GM-CSF in Healthy, HIV-1 Uninfected Volunteers [Completed]

Phase II Study of Fludarabine and Mitoxantrone, Followed by GM-CSF and Rituximab [Recruiting]

Sargramostim Following Allogeneic Bone Marrow Transplantation in Treating Patients With Chronic Myelogenous Leukemia [Active, not recruiting]

CHOP-Rituximab Augmented With GM-CSF in Patients With Previously Untreated Diffuse Large B Cell Non-Hodgkin's Lymphoma [Recruiting]

Topotecan Plus Sargramostim in Treating Patients With Advanced Cancer [Active, not recruiting]

Vaccine Therapy and/or Sargramostim in Treating Patients With Locally Advanced or Metastatic Melanoma [Active, not recruiting]

A Safety/Tolerability and Pharmakokinetic Study of Sargramostim Administrated in the Gingiva [Recruiting]

Halt Growth of Liver Tumors From Uveal Melanoma With Closure of Liver Artery Following Injection of GM-CSF [Recruiting]

Vaccine Therapy With or Without Sargramostim in Treating Patients With Advanced or Metastatic Cancer [Completed]

Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) for Maintenance of Prostate Cancer for Patients Responding to Taxotere [Recruiting]

Vaccination of Patients With Renal Cell Cancer With Dendritic Cell Tumor Fusions and GM-CSF [Recruiting]

GM-CSF With or Without Vaccine Therapy After Combination Chemotherapy and Rituximab as First-Line Therapy in Treating Patients With Stage II, Stage III, or Stage IV Diffuse Large B-Cell Lymphoma [Suspended]

Efficacy Study of Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) for Use in Human IVF [Recruiting]

Rituximab and GM-CSF in Treating Patients With Chronic Lymphocytic Leukemia [Active, not recruiting]

Vaccine Therapy and Sargramostim With or Without Docetaxel in Treating Patients With Metastatic Lung Cancer or Metastatic Colorectal Cancer [Active, not recruiting]

Interferon Alfa Plus Sargramostim in Treating Patients With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia [Active, not recruiting]

The Effectiveness of GM-CSF in HIV-Positive Patients Who Are Also Receiving Anti-HIV Therapy [Completed]

An Open Label Phase I Study of Subcutaneously Administered Recombinant Human GM-CSF in Patients With AIDS Virus Infection and Leukopenia [Completed]

Vaccine Therapy With or Without Sargramostim in Treating Patients With Metastatic Prostate Cancer [Recruiting]

A Phase I Study of the Combination of Recombinant GM-CSF, AZT, and Chemotherapy (ABV) (Adriamycin, Bleomycin, Vincristine) in AIDS and Kaposi's Sarcoma [Completed]

A Pilot Trial Evaluating an Alternating Schedule of Recombinant Human GM-CSF and Azidothymidine in Patients With HIV Infection and Leukopenia [Completed]

A Pilot Study to Evaluate the Effects of Subcutaneously Administered Recombinant Human Granulocyte-Macrophage Colony Stimulating Factor in Pediatric HIV-Infected Patients With Neutropenia Secondary to Azidothymidine [Completed]

Immunotherapy With NK Cell, Rituximab and Rhu-GMCSF in Non-Myeloablative Allogeneic Stem Cell Transplantation [Recruiting]

Proteinase 3 PR1 Peptide Mixed With Montanide ISA-51 VG Adjuvant and Administered With GM-CSF and Peginterferon Alfa-2b [PEG-INTRON(R)] [Recruiting]

GM-CSF in Patients With Pulmonary Alveolar Proteinosis [Recruiting]

Vaccine Therapy and Sargramostim in Treating Patients With Sarcoma or Brain Tumor

GM-CSF and Rituximab After Autologous Stem Cell Transplant in Treating Patients With Relapsed or Refractory Follicular Non-Hodgkin Lymphoma [Recruiting]

GM-CSF in Women With Recurrent Ovary Cancer [Recruiting]

Vaccine Therapy in Treating Patients With Breast Cancer [Recruiting]

Radiation Therapy and Sargramostim in Treating Patients With Advanced Solid Tumors

Study of Aerosolized Sargramostim in Treating Patients With Melanoma Metastatic to the Lung

Phase III Ganciclovir +/- rGM-CSF for AIDS-Related CMV Retinitis [Completed]

PEG-Interferon Alfa-2b, Sargramostim, and Thalidomide in Treating Patients With Metastatic Kidney Cancer [Active, not recruiting]

Vaccine Therapy, Interleukin-2, and Sargramostim in Treating Patients With Advanced Tumors

Vaccine Therapy With or Without Sargramostim in Treating Patients With Stage IIB, Stage IIC, Stage III, or Stage IV Melanoma

Monoclonal Antibody Therapy With Sargramostim and Interleukin-2 in Treating Children With Neuroblastoma [Completed]

Rituximab, Autologous Vaccine Therapy, and Sargramostim in Treating Patients With Recurrent or Refractory Follicular B-Cell Lymphoma

Vaccine Therapy With or Without Sargramostim in Treating Patients Who Have Undergone Surgery for Melanoma

Combination Chemotherapy Followed By Filgrastim or Sargramostim in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia [Active, not recruiting]

Cyclophosphamide, Doxorubicin, Etoposide, and Prednisone OR Cyclophosphamide, Doxorubicin, Vincristine, Prednisone, and Rituximab Followed by Vaccine Therapy Plus Sargramostim in Treating Patients With Stage II, Stage III, or Stage IV Follicular Lymphoma [Recruiting]

A Phase I/II Pilot Study of Simultaneously Administered Rhu GM-CSF ( CHO Cell ) and Azidothymidine ( AZT ) in Patients With Severe HIV Infection and Leukopenia: Pharmacokinetics and Feasibility [Completed]

Combination Chemotherapy Followed By Vaccine Therapy Plus Sargramostim in Treating Patients With Stage III or Stage IV Non-Hodgkin's Lymphoma

Sargramostim in Treating Patients With Kidney Cancer That Has Spread to the Lung [Active, not recruiting]

Granulocyte-Macrophage Colony-Stimulating Factor and Zidovudine: A Phase I Study of Concurrent Administration in Patients With AIDS and Severe ARC [Completed]

Chemotherapy Plus Sargramostim in Treating Patients With Refractory Myeloid Cancer [No longer recruiting]

Phase II Trial of (IL-2) With Priming and (GM-CSF) in Patients With Advanced Melanoma [Recruiting]

Sargramostim in Treating Patients With Chronic Phase Chronic Myelogenous Leukemia Who Are Not in Complete Cytogenetic Remission Following Initial Treatment [No longer recruiting]

Safety and Efficacy Study of GM-CSF, Thalidomide Plus Docetaxel in Prostate Cancer [Recruiting]

Combination Chemotherapy Plus Sargramostim in Treating Patients With Cancer of the Uterus [Completed]

Phenylbutyrate, Dexamethasone, and Sargramostim in Treating Patients With Refractory or Relapsed Acute Myeloid Leukemia [Completed]

GM-CSF and Combination Chemotherapy in Treating Patients Who Are Undergoing Surgery for Stage II or Stage III Colon Cancer [Recruiting]

Ketoconazole, Hydrocortisone, and GM-CSF in Treating Patients With Progressive Prostate Cancer After Hormone Therapy [Active, not recruiting]

Vaccine Therapy Plus GM-CSF in Treating Patients With Multiple Myeloma Undergoing Bone Marrow or Peripheral Stem Cell Transplantation [No longer recruiting]

Vaccine Therapy With or Without Sargramostim in Treating Patients With Cancer [Active, not recruiting]

Combination Chemotherapy and Peripheral Stem Cell Transplantation Followed by Interleukin-2 and Sargramostim in Treating Patients With Inflammatory Stage IIIB or Metastatic Stage IV Breast Cancer [Active, not recruiting]

Vaccine Therapy and Sargramostim After Rituximab in Treating Patients With Refractory or Progressive Non-Hodgkin's Lymphoma [No longer recruiting]

HER-2/Neu Vaccine Plus GM-CSF in Treating Patients With Stage III or Stage IV Breast, Ovarian, or Non-Small Cell Lung Cancer [Active, not recruiting]

Vaccine Therapy and GM-CSF in Treating Patients With Prostate Cancer That Progressed After Surgery and/or Radiation Therapy [Active, not recruiting]

Vaccine Therapy Plus Sargramostim and Interleukin-2 Compared With Nilutamide Alone in Treating Patients With Prostate Cancer [Active, not recruiting]

A Phase I/II Study of Recombinant Human GM-CSF in Patients With AIDS Virus Infection and Leukopenia [Completed]

Activity of TroVax® Alone vs. TroVax® Plus GM-CSF in Patients With Prostate Cancer [No longer recruiting]

A Study to Compare the Effectiveness of a Four Drug Anti-HIV Regimen Given Alone or in Combination With GM-CSF or IL-12 to HIV-Positive Patients [Completed]

Reconstruction of Monocytic Immunocompetence by GM-CSF in Patients With Severe Sepsis and Septic Shock [Recruiting]

Monoclonal Antibody Therapy Plus Sargramostin in Treating Patients With Advanced Neuroblastoma [No longer recruiting]

Inhaled Sargramostim in Treating Patients With Melanoma Metastatic to the Lung [Recruiting]

Vaccine Therapy With gp100 and/or Sargramostim in Treating Patients With Malignant Melanoma [No longer recruiting]

Interleukin-2 and Sargramostim After Chemotherapy in Treating Patients With Stage III or Stage IV Melanoma [Completed]

Interleukin-2, Vinblastine, and GM-CSF in Treating Patients With Metastatic Kidney Cancer [No longer recruiting]

Vaccine Therapy, Chemotherapy, and GM-CSF in Treating Patients With Advanced Pancreatic Cancer [Completed]

Vaccine Therapy and Interleukin-12 With Either Alum or Sargramostim After Surgery in Treating Patients With Melanoma [Completed]

Monoclonal Antibody 3F8 and Sargramostim in Treating Patients With Neuroblastoma [Recruiting]

Monoclonal Antibody 3F8 and GM-CSF in Treating Young Patients With High-Risk, Refractory or Relapsed Neuroblastoma [Recruiting]

Intermittent Chemotherapy With or Without GM-CSF for Metastatic HPRC [Recruiting]

Sargramostim to Prevent Mucositis in Patients Receiving Radiation Therapy for Laryngeal Cancer [No longer recruiting]

GM-CSF Before Surgery in Treating Patients With Localized Prostate Cancer [Recruiting]

Vaccine Therapy and GM-CSF in Treating Patients With Recurrent or Metastatic Melanoma [Recruiting]

GM-CSF and Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Advanced Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer That Did Not Respond to Cisplatin or Carboplatin [Recruiting]

MS-275 and GM-CSF in Treating Patients With Myelodysplastic Syndrome and/or Relapsed or Refractory Acute Myeloid Leukemia [Recruiting]

Vaccine Therapy and GM-CSF in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer That Cannot Be Removed By Surgery [Not yet recruiting]

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