DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more

Leucovorin (Leucovorin Calcium) - Summary

 

-- advertisement --

LEUCOVORIN SUMMARY

LEUCOVORIN CALCIUM TABLETS USP
5 mg, 10 mg, 15 mg, 25 mg

Leucovorin Calcium Tablets USP contain either 5 mg, 10 mg, 15 mg or 25 mg leucovorin as the calcium salt of N-[4-[[(2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl] amino]benzoyl]-L-glutamic acid. This is equivalent to either 5.40 mg, 10.80 mg, 16.21 mg or 27.01 mg of anhydrous leucovorin calcium, respectively.

Leucovorin Calcium Tablets USP are indicated to diminish the toxicity and counteract the effects of impaired methotrexate elimination and of inadvertent overdosages of folic acid antagonists.

LEUCOVORIN NEWS HIGHLIGHTS

Media Articles Related to Leucovorin

Oral Agents as Good as Bolus 5-FU-Leucovorin Regimens for Adjuvant Treatment of Colon Cancer
Source: Medscape Pharmacotherapy Headlines [2004.06.10]

more>>

Published Studies Related to Leucovorin

Randomized phase II study of irinotecan, leucovorin and 5-fluorouracil (ILF) versus cisplatin plus ILF (PILF) combination chemotherapy for advanced gastric cancer. [2008.04]

Preoperative chemoradiotherapy for rectal cancer: randomized trial comparing oral uracil and tegafur and oral leucovorin vs. intravenous 5-fluorouracil and leucovorin. [2008.01.01]

Severe enteropathy among patients with stage II/III colon cancer treated on a randomized trial of bolus 5-fluorouracil/leucovorin plus or minus oxaliplatin: a prospective analysis. [2007.11.01]

A prospective randomised phase III trial of adjuvant chemotherapy with 5-fluorouracil and leucovorin in patients with stage II colon cancer. [2007.10.22]

Phase III study of capecitabine plus oxaliplatin compared with fluorouracil and leucovorin plus oxaliplatin in metastatic colorectal cancer: a final report of the AIO Colorectal Study Group. [2007.09.20]

more>>

Clinical Trials Related to Leucovorin

Study of Taxotere, Cisplatin, 5-Fluorouracil, and Leucovorin for Squamous Cell Carcinoma of the Head and Neck [Completed]

High-Dose Fluorouracil With or Without Leucovorin Compared With Standard Fluorouracil Plus Leucovorin Following Surgery in Treating Patients With Stage III Colon Cancer [Active, not recruiting]

Phase I Irinotecan, 5-Fluorouracil and Leucovorin Combination [Active, not recruiting]

Fluorouracil and Leucovorin and/or Levamisole After Surgery In Treating Patients With Dukes' B Or Dukes' C Colon Cancer [Active, not recruiting]

Irinotecan, 5-Fluorouracil, and Leucovorin in Colorectal Carcinoma [Active, not recruiting]

more>>

Page last updated: 2008-06-22

-- advertisement -- The American Red Cross

We comply with
HONcode standard.
Verify here.
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2008