DOSAGE AND ADMINISTRATION
Initiate treatment at 5 mg once daily, and consider increasing the dose to 10 mg once daily if 5 mg is tolerated.
Tablets may be administered with or without food. Tablets should not be split, crushed, or chewed. Doses higher than 10 mg once daily have not been studied in patients with pulmonary arterial hypertension (PAH).
Pregnancy Testing in Females of Reproductive Potential
Initiate treatment with Letairis in females of reproductive potential only after a negative pregnancy test. Obtain monthly pregnancy tests during treatment [see Use in Specific Populations].
DOSAGE FORMS AND STRENGTHS
5 mg and 10 mg film-coated tablets for oral administration
- Each 5 mg tablet is square convex, pale pink, with "5" on one side and "GSI" on the other side.
- Each 10 mg tablet is oval convex, deep pink, with "10" on one side and "GSI" on the other side.