NEWS HIGHLIGHTS
Published Studies Related to Latisse (Bimatoprost Ophthalmic)
A randomised crossover study comparing bimatoprost and latanoprost in subjects with primary angle closure glaucoma. [2009.06]
BACKGROUND/AIMS: To compare the intraocular pressure (IOP) lowering efficacy and side effects of latanoprost 0.005% and bimatoprost 0.03% in subjects with chronic primary angle closure glaucoma (PACG)... CONCLUSIONS: Bimatoprost once daily was similarly effective in reducing IOP compared with latanoprost once daily in subjects with chronic PACG. Both drugs were well tolerated with mild ocular adverse events.
Effect of bimatoprost on intraocular pressure after cataract surgery. [2008.12]
BACKGROUND: An increase in intraocular pressure (IOP) frequently occurs after otherwise uneventful phacoemulsification cataract surgery. This study was conducted to determine the efficacy of bimatoprost 0.03% drops given preoperatively in preventing IOP rise following phacoemulsification cataract surgery... INTERPRETATION: When compared with placebo, prophylactic use of 1 drop of bimatoprost before phacoemulsification cataract surgery failed to produce a significantly different effect on IOP levels from placebo at 3 hours postoperatively, but it caused a significant IOP reduction at 24 hours.
Long-term efficacy and safety of bimatoprost for intraocular pressure lowering in glaucoma and ocular hypertension: year 4. [2008.10]
BACKGROUND: Bimatoprost 0.03% has been shown to consistently reduce mean intraocular pressure (IOP) more than timolol 0.5% over 2 years. To further evaluate long-term safety and efficacy, once-daily bimatoprost 0.03% was compared with timolol 0.5% twice daily through year 4... CONCLUSION: Bimatoprost once daily provided sustained IOP lowering greater than timolol twice daily and was well tolerated over long-term use.
A comparison of dorzolamide/timolol-fixed combination versus bimatoprost in patients with open-angle glaucoma who are poorly controlled on latanoprost. [2008.08]
PURPOSE: The aim of this study was to evaluate the intraocular pressure (IOP) efficacy and safety of dorzolamide/timolol in fixed combination (DTFC) versus bimatoprost in open-angle glaucoma (OAG) patients poorly controlled (> or =21 mmHg) on latanoprost... CONCLUSIONS: This study suggests that OAG patients generally can obtain similar IOP control at individual time points (when a Bonferroni correction is considered) by switching to either DTFC or bimatoprost, but overall diurnal control is statistically better with bimatoprost.
Comparative study of the stability of bimatoprost 0.03% and latanoprost 0.005%: a patient-use study. [2008.06.11]
BACKGROUND: The stability of ophthalmic preparations in multidose containers is influenced by the preservative as well as the stability of the active ingredient. Unstable drugs may require refrigeration to preserve their active ingredient level and they are more likely to degrade over time, therefore becoming more susceptible to degradation based on patient mishandling. The purpose of this study was to determine the degree of molecular degradation that occurs in bimatoprost and latanoprost in a patient-use setting... CONCLUSION: This study showed that bimatoprost maintained > or =100% concentration throughout the study period while latanoprost did not.
Clinical Trials Related to Latisse (Bimatoprost Ophthalmic)
Intraocular Pressure Reduction With the Bimatoprost/Timolol Fixed Combination [Recruiting]
The purpose of this study is to examine the ocular hypotensive effect of Bimatoprost and the
potential additional effect of the Bimatoprost/Timolol fixed combination in eyes with ocular
hypertension, primary open angle glaucoma or exfoliation glaucoma.
Safety and Efficacy Study of Bimatoprost to Treat Hypotrichosis of the Eyelashes After Application to the Eyelid Margin [Recruiting]
This one-year study evaluates the long-term safety and effectiveness of bimatoprost solution
application to the eyelid margin (where the eyelashes meet the skin) to treat hypotrichosis
of the eyelashes (inadequate or not enough eyelashes). There will be two different types of
subjects participating in the study 1)those with inadequate eyelashes due to natural causes
or 2) those with inadequate eyelashes following a complete course of chemotherapy treatment.
There will be two treatment periods of six months each. Subjects will receive either the
study medication or vehicle in either of the two treatment periods.
The Effects of Xalatan, Travatan and Lumigan on Skin Pigmentation Near the Eye [Recruiting]
Study of Bimatoprost Solution in Increasing Eyelash Prominence in African Americans With Eyelash Hypotrichosis [Not yet recruiting]
This study will evaluate the safety and efficacy of bimatoprost solution 0. 03% once daily to
the upper eyelid margins (where the eyelashes meet the skin) compared with vehicle in
increasing overall eyelash prominence in self-identified African American/ethnic black
subjects exhibiting hypotrichosis of the eyelashes (inadequate or not enough eye lashes).
Safety and Efficacy of AGN 210699 Ophthalmic Solution in Patients With Ocular Hypertension or Primary Open-Angle Glaucoma [Recruiting]
The study will evaluate the safety and efficacy of AGN 210669 ophthalmic solution in
comparison with AGN 210669 vehicle and bimatoprost ophthalmic solution dosed once-daily each
morning, in subjects with ocular hypertension or primary open-angle glaucoma. Subjects will
be followed for 2 weeks.
|
PATIENT REVIEWS / RATINGS / COMMENTSBased on a total of 1 ratings/reviews, Latisse has an overall score of 10. The effectiveness score is 8 and the side effect score is 10. The scores are on ten point scale: 10 - best, 1 - worst.
| | Latisse review by 33 year old female patient | | | Rating |
| Overall rating: | |  |
| Effectiveness: | | Considerably Effective |
| Side effects: | | No Side Effects | | |
Treatment Info |
| Condition / reason: | | eyelash loss |
| Dosage & duration: | | one drop brushed on eyelash base (dosage frequency: 1x per day) for the period of 3mos |
| Other conditions: | | none |
| Other drugs taken: | | none | | |
Reported Results |
| Benefits: | | within a month of starting treatment eyelashes started to grow thicker, longer and darker |
| Side effects: | | had occassional slight itching after application, but not consistently so and it wasn't all that bothersome |
| Comments: | | put one drop of product on an eyeliner brush, then brushed across each eyelid at the base of the eyelashes. applied daily |
|
|
