Media Articles Related to Laryng-O-Jet (Lidocaine Topical)
Combining dental, medical procedures may safely limit children's anesthesia exposure
Source: Dentistry News From Medical News Today [2016.10.27]
Children who require both dental and non-dental medical procedures should have them completed under one general anesthesia session whenever possible, which is ideal for both the patient and family...
Trends in Tramadol: Pharmacology, Metabolism, and Misuse
Source: Medscape Anesthesiology Headlines [2017.02.15]
Learn about the unique characteristics of tramadol, its pharmacogenomic considerations, and its potential for abuse in this comprehensive review.
Anesthesia & Analgesia
UW study: Incidence of consciousness during surgery lower than previous estimates
Source: Pain / Anesthetics News From Medical News Today [2016.12.19]
An international study of 260 surgical patients found that, contrary to many previous studies, just more than four percent were conscious of the external world while under general anesthesia but...
Published Studies Related to Laryng-O-Jet (Lidocaine Topical)
Lidocaine/tetracaine peel in topical anesthesia prior to laser-assisted hair
removal: Phase-II and Phase-III study results. 
peel"), which air-dries and can be peeled off 30 min post-application... CONCLUSIONS: After a 30-min application, LT peel was effective and well-tolerated
Cervical lidocaine for IUD insertional pain: a randomized controlled trial. 
intracervical 2% lidocaine gel for pain relief with IUD insertion... CONCLUSION: Topical or intracervical 2% lidocaine gel prior to IUD insertion does
Treatment for postoperative wound pain in gynecologic laparoscopic surgery:
topical lidocaine patches. 
CONCLUSIONS: Topical lidocaine patches at the laparoscopic port sites reduced
Lidocaine/tetracaine patch (Rapydan) for topical anaesthesia before arterial
access: a double-blind, randomized trial. 
non-inferior to subcutaneous local anaesthetic... CONCLUSIONS: Both the lidocaine/tetracaine patch and subcutaneous injection of
Intracervical lidocaine gel for intrauterine device insertion: a randomized
controlled trial. 
decreased insertion pain compared to placebo... CONCLUSIONS: Intracervical 2% lidocaine gel does not decrease IUD insertion pain.
Clinical Trials Related to Laryng-O-Jet (Lidocaine Topical)
Tumescent Lidocaine Maximum Safe mg/kg Dosage [Enrolling by invitation]
This pharmacokinetic clinical trial is a dose ranging study of lidocaine in tumescent local
anesthesia. The goal is to understand the absorption pharmacokinetic of tumescent lidocaine
and to determine an objective (statistical) estimate of the maximum safe mg/kg dosage of
lidocaine in tumescent local anesthesia without liposuction.
Lidocaine Infusion as a Treatment for Cocaine Relapse and Craving [Recruiting]
We propose that the systemic administration of lidocaine following the induction of
cue-induced craving, relative to saline plus cue-induced craving or lidocaine without
cue-induced craving, will block the reconsolidation of cue memories. This will lead to a
reduction in cue-induced craving upon repeated testing as well as subsequent cocaine use and
Lidocaine: Effect of Lidocaine in Chronic Cough [Completed]
People cough in order to clear their airways. Most coughs are caused by viruses and settle
down by themselves, but some people develop persistent coughing which can be anywhere from 8
weeks to several years. This is called chronic cough. People with chronic cough find the
symptom distressing and it can have a major impact on their quality of life. Patients with
chronic cough often report a sensation at the back of their throat which makes them feel an
urge to cough. There is some evidence that Lidocaine (an anaesthetic used during medical
procedures) can suppress a person's cough when given to patients via a nebuliser (a machine
that turns liquid into a fine mist).
It is currently unknown whether using a local anaesthetic, such as Lidocaine, in the form of
a throat spray would successfully suppress a person's cough. A throat spray would be an
easier treatment option in chronic cough patients. Thus, the investigators research aims to
compare cough rates, severity and urge to cough scores between Lidocaine throat spray and
Lidocaine Infusion for Chronic Pain in Opioid Dependent Patients [Recruiting]
Prescription drug abuse represents a major healthcare problem, with treatment costs reaching
billions of dollars annually in the United States alone. Today opioids are commonly
prescribed for chronic non-cancer pain and are only partially effective for short-term pain
relief. Whereas opioids are initially part of the solution for pain, it eventually often
turns to be a problem in patient with chronic pain. Long-term treatment with opioids can be
complicated by development of tolerance, dependency, addiction, abnormal pain sensitivity,
hormonal changes, and immune modulation. Unfortunately, the chronic use of anti-inflammatory
drugs is associated with a marked increase in adverse effects.
The purpose of this study is to determine whether systemic administration of lidocaine
provides effective pain relief in opioid dependent chronic pain patients. Investigators
intend to demonstrate that lidocaine infusion can improve pain relief and physical function
in opioid dependent patients, thus improving compliance and patient satisfaction, which may
potentially help wean patients off narcotics. The long-term goal of this proposal is to
decrease opioid dependence in chronic pain patients by using lidocaine infusion.
Intra-arterial Lidocaine for Pain Control Post Uterine Fibroid Embolization [Recruiting]
Uterine artery embolization (UAE) is a minimally invasive treatment for women with
symptomatic fibroids. It is similar to hysterectomy in term of satisfaction and symptoms
improvement, with fewer complications and at lower cost. However, the majority of women
undergoing UFE experience important pain after the procedure despite optimal analgesia, with
one third reporting pain equal or worse than labor. Pain is the more common cause of
prolonged hospital stay or readmission. There is need for a simple, efficient way to reduce
For this prospective randomized study, the hypothesis is that an anesthetic drug, lidocaine,
injected in the uterine arteries diminishes pain post-UFE. Patients will be randomized in 3
groups: control, lidocaine injected during embolization, and lidocaine injected after
embolization. Pain will be evaluated using a validated scale at 4h and 24h
post-intervention. Hospital length-of-stay and total narcotic dose administered will be
evaluated in the three groups.
This is the first Canadian study evaluating lidocaine use for pain control in UFE patients.
Results will be transferable to clinical practice, considering the use of lidocaine is
simple and cost is negligible. It could have a great impact on pain management in women
undergoing UFE in all practice settings.