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Lamprene (Clofazimine) - Summary

 


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LAMPRENE SUMMARY

Lamprene®

Lamprene, clofazimine, is an antileprosy agent available as soft gelatin capsules for oral administration. Each capsule contains 50 mg of micronized clofazimine suspended in an oil-wax base. Clofazimine is a substituted iminophenazine bright-red dye.

Lamprene is indicated in the treatment of lepromatous leprosy, including dapsone-resistant lepromatous leprosy and lepromatous leprosy complicated by erythema nodosum leprosum. Lamprene has not been demonstrated to be effective in the treatment of other leprosy-associated inflammatory reactions.

      Combination drug therapy has been recommended for initial treatment of multibacillary leprosy to prevent the development of drug resistance.


See all Lamprene indications & dosage >>

LAMPRENE NEWS HIGHLIGHTS

Published Studies Related to Lamprene (Clofazimine)

Two-year combination antibiotic therapy with clarithromycin, rifabutin, and clofazimine for Crohn's disease. [2007.06]

Double-blind, randomized, controlled clinical trial of clofazimine compared with chloroquine in patients with systemic lupus erythematosus. [2005.10]

Does clofazimine (B663) reach Mycobacterium leprae persisting in Schwann cells and endothelial cells of endoneurial blood vessels in peripheral nerves? [2008.08]

[Melkersson-Rosenthal syndrome treated with clofazimine] [2008.01.14]

Photosensitisation induced by clofazimine in a cat. [2007.09]

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Clinical Trials Related to Lamprene (Clofazimine)

A Randomized Controlled Prophylactic Study of Clofazimine To Prevent Mycobacterium Avium Complex Infection in HIV Disease [Completed]

A Phase II/III Trial of Rifampin, Ciprofloxacin, Clofazimine, Ethambutol, and Amikacin in the Treatment of Disseminated Mycobacterium Avium Infection in HIV-Infected Individuals. [Completed]

The Safety and Effectiveness of Clarithromycin Plus Ethambutol Used With or Without Clofazimine in the Treatment of MAC in Patients With AIDS [Completed]

Uniform Multidrug Therapy Regimen for Leprosy Patients [Recruiting]

Clofazamine for the Treatment of Mycobacterium Avium Intracellulare(MAI) [Completed]

more >>

Page last updated: 2008-11-03

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