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Lamictal (Lamotrigine) - Published Studies

 
 



Lamictal Related Published Studies

Well-designed clinical trials related to Lamictal (Lamotrigine)

Analysis of three lamotrigine extended-release clinical trials: comparison of pragmatic ITT and LOCF methodologies. [2012]

Longitudinal changes in magnetisation transfer ratio in secondary progressive multiple sclerosis: data from a randomised placebo controlled trial of lamotrigine. [2012]

Efficacy and safety of pregabalin versus lamotrigine in patients with newly diagnosed partial seizures: a phase 3, double-blind, randomised, parallel-group trial. [2011.10]

A double-blind placebo-controlled trial of lamotrigine as an antidepressant augmentation agent in treatment-refractory unipolar depression. [2011.10]

Effects of lamotrigine and phenytoin on the pharmacokinetics of atorvastatin in healthy volunteers. [2011.07]

Long-term outcome of bipolar depressed patients receiving lamotrigine as add-on to lithium with the possibility of the addition of paroxetine in nonresponders: a randomized, placebo-controlled trial with a novel design. [2011.02]

Pregabalin effect on steady-state pharmacokinetics of carbamazepine, lamotrigine, phenobarbital, phenytoin, topiramate, valproate, and tiagabine. [2011.02]

Lamotrigine in the immediate treatment of outpatients with depersonalization disorder without psychiatric comorbidity: randomized, double-blind, placebo-controlled study. [2011.02]

Cognitive and behavioral effects of lamotrigine and carbamazepine monotherapy in patients with newly diagnosed or untreated partial epilepsy. [2011.01]

Lamotrigine in the immediate treatment of outpatients with depersonalization disorder without psychiatric comorbidity: randomized, double-blind, placebo-controlled study. [2011]

Adjunctive lamotrigine XR for primary generalized tonic-clonic seizures in a randomized, placebo-controlled study. [2010.11]

Effects of lamotrigine on hippocampal activation in corticosteroid-treated patients. [2010.11]

A comparison of pregabalin, lamotrigine, and placebo as adjunctive therapy in patients with refractory partial-onset seizures. [2010.09]

Efficacy and safety of two treatment algorithms in bipolar depression consisting of a combination of lithium, lamotrigine or placebo and paroxetine. [2010.09]

A double-blind, placebo-controlled trial of lamotrigine for pathological skin picking: treatment efficacy and neurocognitive predictors of response. [2010.08]

Lamotrigine versus lithium as maintenance treatment in bipolar I disorder: an open, randomized effectiveness study mimicking clinical practice. The 6th trial of the Danish University Antidepressant Group (DUAG-6). [2010.08]

Lamotrigine for neuroprotection in secondary progressive multiple sclerosis: a randomised, double-blind, placebo-controlled, parallel-group trial. [2010.07]

A fMRI evaluation of lamotrigine for the treatment of trigeminal neuropathic pain: pilot study. [2010.06]

Genetic association study of treatment response with olanzapine/fluoxetine combination or lamotrigine in bipolar I depression. [2010.05]

Interleaved transcranial magnetic stimulation and fMRI suggests that lamotrigine and valproic acid have different effects on corticolimbic activity. [2010.04]

Levetiracetam, lamotrigine, and phenobarbital in patients with epileptic seizures and Alzheimer's disease. [2010.04]

Ethosuximide, valproic acid, and lamotrigine in childhood absence epilepsy. [2010.03.04]

Antiepileptic drugs and quality of life in the elderly: results from a randomized double-blind trial of carbamazepine and lamotrigine in patients with onset of epilepsy in old age. [2010.03]

Effects of charcoal on the absorption and elimination of the antiepileptic drugs lamotrigine and oxcarbazepine. [2010]

Lamotrigine for neuroprotection in secondary progressive multiple sclerosis: a randomised, double-blind, placebo-controlled, parallel-group trial. [2010]

Levetiracetam, lamotrigine, and phenobarbital in patients with epileptic seizures and Alzheimer's disease. [2010]

The effect of raltegravir on the glucuronidation of lamotrigine. [2009.10]

A preliminary study of lamotrigine in the treatment of affective instability in borderline personality disorder. [2009.09]

Cardiac function and antiepileptic drug treatment in the elderly: a comparison between lamotrigine and sustained-release carbamazepine. [2009.08]

[Valproic acid versus lamotrigine as a monotherapy for absence epilepsy in children] [2009.08]

Olanzapine/fluoxetine combination vs. lamotrigine in the 6-month treatment of bipolar I depression. [2009.07]

Attenuation of amygdala atrophy with lamotrigine in patients receiving corticosteroid therapy. [2009.06]

A double-blind randomized trial of mood stabilizer augmentation using lamotrigine and valproate for patients with schizophrenia who are stabilized and partially responsive. [2009.06]

Lamotrigine in the treatment of binge-eating disorder with obesity: a randomized, placebo-controlled monotherapy trial. [2009.05]

Lamotrigine and valproate pharmacokinetics interactions in epileptic patients. [2009.04]

Effects of valproate or lamotrigine monotherapy on the reproductive endocrine and insulin-related metabolic profile in Chinese adults with epilepsy: a prospective randomized study. [2009.04]

Lamotrigine and valproic acid have different effects on motorcortical neuronal excitability. [2009.04]

The efficacy of lamotrigine in clozapine-resistant schizophrenia: a systematic review and meta-analysis. [2009.04]

Effects of lamotrigine compared with levetiracetam on anger, hostility, and total mood in patients with partial epilepsy. [2009.03]

Efficacy and safety of lamotrigine as add-on treatment to lithium in bipolar depression: a multicenter, double-blind, placebo-controlled trial. [2009.02]

The efficacy of lamotrigine in clozapine-resistant schizophrenia: A systematic review and meta-analysis. [2009.01.29]

A single blind comparison of lithium and lamotrigine for the treatment of bipolar II depression. [2008.12]

Bioequivalence of generic lamotrigine 100-mg tablets in healthy Thai male volunteers: a randomized, single-dose, two-period, two-sequence crossover study. [2008.10]

Lamotrigine does not prolong QTc in a thorough QT/QTc study in healthy subjects. [2008.09]

Attenuation of the effects of corticosteroids on declarative memory with lamotrigine. [2008.09]

Hyperandrogenism, ovulatory dysfunction, and polycystic ovary syndrome with valproate versus lamotrigine. [2008.08]

Efficacy of lamotrigine in the management of chemotherapy-induced peripheral neuropathy: a phase 3 randomized, double-blind, placebo-controlled trial, N01C3. [2008.06.15]

Adjunctive lamotrigine for partial seizures in patients aged 1 to 24 months. [2008.05.27]

Population pharmacokinetics of lamotrigine in elderly patients. [2008.04]

Olanzapine or lamotrigine addition to lithium in remitted bipolar disorder patients with anxiety disorder comorbidity: a randomized, single-blind, pilot study. [2008.04]

[A retrospective study of the effectiveness of lamotrigine in monotherapy for the treatment of epileptic seizures. The ERELMO study] [2008.02.16]

Six-month prospective life charting of mood symptoms with lamotrigine monotherapy versus placebo in rapid cycling bipolar disorder. [2008.01.01]

Open-label, concomitant use of lamotrigine and other medications for bipolar disorder. [2008.01]

Efficacy and safety of antidepressant augmentation with lamotrigine in patients with treatment-resistant depression: a randomized, placebo-controlled, double-blind study. [2008]

Adjunctive lamotrigine for partial seizures in patients aged 1 to 24 months. [2007.12.12]

Lamotrigine as add-on therapy in schizophrenia: results of 2 placebo-controlled trials. [2007.12]

Lack of pharmacokinetic interaction of levetiracetam on carbamazepine, valproic acid, topiramate, and lamotrigine in children with epilepsy. [2007.11]

Double-blind, placebo-controlled trial of lamotrigine in combination with other medications for neuropathic pain. [2007.10]

A randomized, double-blind, placebo-controlled, two-period, crossover, pilot trial of lamotrigine in patients with central pain due to multiple sclerosis. [2007.09]

Double-Blind, Placebo-Controlled Trial of Lamotrigine in Combination with Other Medications for Neuropathic Pain. [2007.07.25]

Lack of Pharmacokinetic Interaction of Levetiracetam on Carbamazepine, Valproic Acid, Topiramate, and Lamotrigine in Children with Epilepsy. [2007.07.25]

An international multicenter randomized double-blind controlled trial of lamotrigine and sustained-release carbamazepine in the treatment of newly diagnosed epilepsy in the elderly. [2007.07]

The effect of lamotrigine augmentation of clozapine in a sample of treatment-resistant schizophrenic patients: a double-blind, placebo-controlled study. [2007.07]

Monotherapy of lamotrigine versus carbamazepine in patients with poststroke seizure. [2007.07]

Effectiveness and weight effects of open-label lamotrigine with and without concomitant psychotropic medications in patients with bipolar I disorder. [2007.05.22]

The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: an unblinded randomised controlled trial. [2007.03.24]

The effect of lamotrigine augmentation of clozapine in a sample of treatment-resistant schizophrenic patients: A double-blind, placebo-controlled study. [2007.03.23]

Oral contraceptives induce lamotrigine metabolism: evidence from a double-blind, placebo-controlled trial. [2007.03]

Lamotrigine for treatment of pain associated with diabetic neuropathy: results of two randomized, double-blind, placebo-controlled studies. [2007.03]

Lamotrigine in patients with epilepsy and comorbid depressive symptoms. [2007.02]

Variation in lamotrigine plasma concentrations with hormonal contraceptive monthly cycles in patients with epilepsy. [2006.09]

Lamotrigine as an add-on treatment for depersonalization disorder: a retrospective study of 32 cases. [2006.09]

Adjunctive treatment for mood stabilization of patients with bipolar I disorder treated with lamotrigine. [2006.09]

Cognitive effects of lamotrigine compared with topiramate in patients with epilepsy. [2006.08.08]

Lopinavir/ritonavir reduces lamotrigine plasma concentrations in healthy subjects. [2006.08]

Lamotrigine adjunctive therapy among children and adolescents with primary generalized tonic-clonic seizures. [2006.08]

A 7-week, randomized, double-blind trial of olanzapine/fluoxetine combination versus lamotrigine in the treatment of bipolar I depression. [2006.07]

Impact of lamotrigine and lithium on weight in obese and nonobese patients with bipolar I disorder. [2006.07]

Effect of lamotrigine on cognition in children with epilepsy. [2006.05.23]

Distinct cognitive neurophysiologic profiles for lamotrigine and topiramate. [2006.04]

Pharmacokinetics and tolerability of lamotrigine and olanzapine coadministered to healthy subjects. [2006.04]

Effects of lamotrigine and lithium on body weight during maintenance treatment of bipolar I disorder. [2006.04]

The effect of dermatologic precautions on the incidence of rash with addition of lamotrigine in the treatment of bipolar I disorder: a randomized trial. [2006.03]

Effects of clozapine plus lamotrigine on phencyclidine-induced hyperactivity. [2006.03]

A single-center, double-blind, placebo-controlled evaluation of lamotrigine in the treatment of obesity in adults. [2006.02]

Treatment-resistant bipolar depression: a STEP-BD equipoise randomized effectiveness trial of antidepressant augmentation with lamotrigine, inositol, or risperidone. [2006.02]

Subjective preference for lamotrigine or topiramate in healthy volunteers: Relationship to cognitive and behavioral functioning. [2006.02]

Lamotrigine versus carbamazepine monotherapy for epilepsy. [2006.01.25]

Double-blind, placebo-controlled study of lamotrigine in primary generalized tonic-clonic seizures. [2005.12.13]

Lack of pharmacokinetic interaction between oxcarbazepine and lamotrigine. [2005.12]

The LAM-SAFE Study: lamotrigine versus carbamazepine or valproic acid in newly diagnosed focal and generalised epilepsies in adolescents and adults. [2005.12]

Effects of clozapine plus lamotrigine on phencyclidine-induced hyperactivity. [2005.11.19]

Cognitive and behavioral effects of lamotrigine and topiramate in healthy volunteers. [2005.06.28]

New onset geriatric epilepsy: a randomized study of gabapentin, lamotrigine, and carbamazepine. [2005.06.14]

Lamotrigine treatment of aggression in female borderline-patients: a randomized, double-blind, placebo-controlled study. [2005.05]

A medication screening trial evaluation of reserpine, gabapentin and lamotrigine pharmacotherapy of cocaine dependence. [2005.03]

In vivo biopharmaceutical characterisation of a new formulation containing the antiepileptic drug lamotrigine in comparison to plain and dispersible/chewable lamotrigine tablets. [2005]

Effects of lamotrigine on the symptoms and life qualities of patients with post polio syndrome: a randomized, controlled study. [2005]

Placebo-controlled trial of lamotrigine added to conventional and atypical antipsychotics in schizophrenia. [2004.09.15]

Lamotrigine versus valproic acid as first-line monotherapy in newly diagnosed typical absence seizures: an open-label, randomized, parallel-group study. [2004.09]

Efficacy and tolerability of conversion to monotherapy with lamotrigine compared with valproate and carbamazepine in patients with epilepsy. [2004.08]

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