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Klaron (Sulfacetamide Sodium Topical) - Summary

 
 



KLARON SUMMARY

Each mL of Klaron® (sodium sulfacetamide lotion) Lotion, 10% contains 100 mg of sodium sulfacetamide in a vehicle consisting of purified water; propylene glycol; lauramide DEA (and) diethanolamine; polyethylene glycol 400, monolaurate; hydroxyethyl cellulose; sodium chloride; sodium metabisulfite; methylparaben; xanthan gum; EDTA and simethicone. Sodium sulfacetamide is a sulfonamide with antibacterial activity.

Klaron Lotion is indicated in the topical treatment of acne vulgaris.


See all Klaron indications & dosage >>

NEWS HIGHLIGHTS

Media Articles Related to Klaron (Sulfacetamide Topical)

Spironolactone: The 'Other' Hormonal Acne Therapy
Source: MedPageToday.com - medical news plus CME for physicians [2015.08.28]
(MedPage Today) -- Expert: drug is effective and its safety issues can be managed

Acne Pictures Slideshow: Quick Cover-ups, Do's and Don'ts
Source: MedicineNet Acne Specialty [2015.08.14]
Title: Acne Pictures Slideshow: Quick Cover-ups, Do's and Don'ts
Category: Slideshows
Created: 8/1/2012 12:00:00 AM
Last Editorial Review: 8/14/2015 12:00:00 AM

Experimental Treatment Uses Nitric Oxide for Acne
Source: MedicineNet Acne Specialty [2015.08.03]
Title: Experimental Treatment Uses Nitric Oxide for Acne
Category: Health News
Created: 7/31/2015 12:00:00 AM
Last Editorial Review: 8/3/2015 12:00:00 AM

Could a Vitamin Play a Role in Acne Outbreaks?
Source: MedicineNet Acne Specialty [2015.06.25]
Title: Could a Vitamin Play a Role in Acne Outbreaks?
Category: Health News
Created: 6/24/2015 12:00:00 AM
Last Editorial Review: 6/25/2015 12:00:00 AM

Acne patients: 'substantial proportion' fail to collect prescribed treatment
Source: Compliance News From Medical News Today [2015.03.22]
Dermatologist-prescribed treatments are being left on pharmacy shelves by up to a quarter of people with acne, according to a new study.

more news >>

Published Studies Related to Klaron (Sulfacetamide Topical)

Combination sodium sulfacetamide 10% and sulfur 5% cream with sunscreens versus metronidazole 0.75% cream for rosacea. [2005.06]
Topical metronidazole and combination sodium sulfacetamide and sulfur commonly are used to treat rosacea. Recently, the relative efficacy and safety of sodium sulfacetamide 10% and sulfur 5% cream with sunscreens (Rosac Cream) (n = 75) and metronidazole 0.75% cream (Metrocream) (n = 77) were compared in an investigator-blinded, randomized, parallel-group study at 6 sites...

Interaction of topical sulfacetamide and topical dapsone with benzoyl peroxide. [2009.09]
CONCLUSIONS: Knowledge of the chemical reaction between benzoyl peroxide and sulfacetamide and dapsone will help minimize the occurrence of this interaction on our patients' skin.

Treatment of papulopustular rosacea with sodium sulfacetamide 10%/sulfur 5% emollient foam. [2009.03]
Acne rosacea is a chronic cutaneous disorder affecting as many as 14 million Americans.The high patient satisfaction ratings for SSSE foam suggest that the product may improve long-term compliance rates, with the potential to yield more favorable clinical outcomes.

Evaluating the role of topical therapies in the management of rosacea: focus on combination sodium sulfacetamide and sulfur formulations. [2004.01]
The combination of sodium sulfacetamide and sulfur is unique in the rosacea armamentarium because of its dual use as topical therapy and therapeutic cleanser. Several formulations of sulfacetamide 10% and sulfur 5% are now available as topical lotions and cleansers.The sulfacetamide/sulfur cleansers serve as adjunctive therapy by providing additive effects to other topical and oral therapies for rosacea with favorable tolerability and cosmetic appeal.

Measurement of aqueous humor flow following scleral injection of sulfacetamide as marker: effect of methazolamide, timolol, and pilocarpine. [1989.01]
A simple technique for rapid determination of the flow of aqueous humor (AH) in rabbits is described. Data from control eyes and eyes treated with known inhibitors of aqueous humor production are presented as evidence of the suitability of the technique for comparing the influence of other drugs on aqueous flow.

more studies >>

Clinical Trials Related to Klaron (Sulfacetamide Topical)

Effects of Hyperbaric Oxygen Therapy on Surgical Wound Healing [Enrolling by invitation]
The aim of this study is to test the effect of Hyperbaric Oxygen Therapy) HBOT (100% oxygen; 2. 0 ATA; 90 minute total exposure) and compare against a hyperbaric sham treatment (HBST) (patient's breathing room air; 2. 0 ATA; 90 minute exposure) in reducing edema and ecchymosis. HBOT will be applied as a single pre-operative and a single post-operative treatment for patients undergoing eyelid surgery. Briefly, patients will be exposed to HBOT 2-4 hours prior to undergoing surgery, 2-4 hours post-surgery and healing will be assessed at day 3, 10, 21, 30 & 90 days after surgery. Edema and ecchymosis will be assessed in a time series to determine the extent that HBOT reduces these clinical signs. The primary null hypothesis to test will be that no differences in scores will exist between treatment and control at day 3, 10 & 21 post-surgery. A secondary null hypothesis to test is the time required to change a score will be no different between the two groups. HBOT=hyperbaric oxygen therapy; HBST=hyperbaric sham treatment

Patients Response to Early Switch To Oral:Osteomyelitis Study [Not yet recruiting]
Based on the current literature, investigators hypothesize that patients with osteomyelitis who are treated with the standard approach of intravenous antibiotics for the full duration of therapy will have the same clinical outcomes as patients treated with the experimental approach of intravenous antibiotics with early switch to oral antibiotics. The primary objective of this study is to compare patients with osteomyelitis treated with the standard approach of intravenous antibiotics for the full duration of therapy versus patients treated with intravenous antibiotics with an early switch to oral antibiotics in relation to clinical outcomes at 12 months after discontinuation of antibiotic therapy. Secondary objectives of the study include the evaluation of adverse events related to the use of antibiotics as well as the cost of care evaluated from the hospital perspective.

Intraductal Meibomian Gland Probing Trial [Active, not recruiting]
In this research study, the investigators are looking at the effects of Meibomian Gland Probing (MGP) versus a sham (fake) procedure in patients with refractory MGD who have already tried traditional management with no success in resolving their clinical signs (as seen by their ophthalmologist) or their symptoms. The investigators are also evaluating the effects of using two (2) post-procedural medication treatments: Blephamide or GenTeal PM Night-Time to determine if treatment after the MGP procedure has an effect on its outcome.

The Effect of Sodium Thiosulfate Eardrops on Hearing Loss in Patients Who Receive Cisplatin Therapy [Terminated]
This is a pilot, randomized, self-controlled study of the effects of intratympanic sodium thiosulfate (STS) on the degree of hearing loss in patients receiving cisplatin therapy. Sodium thiosulfate is an inactive ingredient contained in sulfacetamide ophthalmic solution which is used routinely as an otic solution delivered to the middle ear space. The hypothesis of this study is that local administration of sodium thiosulfate (STS) will result in improved hearing compared to ears not receiving the study drug in patients receiving systemic cisplatin therapy.

ORCA - Oracea« for Rosacea: A Community-based Assessment [Completed]
The objective of this study is to assess the effectiveness, safety, subject satisfaction and quality of life with Oracea« when used as monotherapy or as add-on therapy to existing topical regimens for the treatment of rosacea.

more trials >>


PATIENT REVIEWS / RATINGS / COMMENTS

Based on a total of 3 ratings/reviews, Klaron has an overall score of 8.67. The effectiveness score is 8.67 and the side effect score is 8.67. The scores are on ten point scale: 10 - best, 1 - worst.
 

Klaron review by 28 year old female patient

  Rating
Overall rating:  
Effectiveness:   Highly Effective
Side effects:   No Side Effects
  
Treatment Info
Condition / reason:   acne
Dosage & duration:   a thin film to affected area twice a day (dosage frequency: twice a day) for the period of two years
Other conditions:   none
Other drugs taken:   orthotricyclene
  
Reported Results
Benefits:   Acne cleared up remarkably, pretty much disappeared altogether.
Side effects:   No side effects.
Comments:   It took about two to three months to see any improvement, but improvement was steady until my acne was completely cleared up.

 

Klaron review by 25 year old female patient

  Rating
Overall rating:  
Effectiveness:   Considerably Effective
Side effects:   Moderate Side Effects
  
Treatment Info
Condition / reason:   Skin Problem
Dosage & duration:   Topical application (dosage frequency: twice a day) for the period of One Year
Other conditions:   Skin condition only
Other drugs taken:   None
  
Reported Results
Benefits:   Reduced bad boils and acne on the skin surface
Side effects:   Drying of the skin, some redness and some skin irritation
Comments:   This lotion was applied to cleansed skin topically twice a day for a period of one year. The result was the drying of and reduction of very bad acne and skin boil breakouts with the side effect of red, dried and slightly sensitive skin. This was reduced by using a non allergenic topical skin moisturizer which alleviated the side effects

 

Klaron review by 25 year old female patient

  Rating
Overall rating:  
Effectiveness:   Considerably Effective
Side effects:   Moderate Side Effects
  
Treatment Info
Condition / reason:   Skin Problem
Dosage & duration:   Topical application (dosage frequency: twice a day) for the period of One Year
Other conditions:   Skin condition only
Other drugs taken:   None
  
Reported Results
Benefits:   Reduced bad boils and acne on the skin surface
Side effects:   Drying of the skin, some redness and some skin irritation
Comments:   This lotion was applied to cleansed skin topically twice a day for a period of one year. The result was the drying of and reduction of very bad acne and skin boil breakouts with the side effect of red, dried and slightly sensitive skin. This was reduced by using a non allergenic topical skin moisturizer which alleviated the side effects

See all Klaron reviews / ratings >>

Page last updated: 2015-08-28

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