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Ketamine (Ketamine Hydrochloride) - Side Effects and Adverse Reactions

 
 



ADVERSE REACTIONS

Cardiovascular

Blood pressure and pulse rate are frequently elevated following administration of ketamine alone. However, hypotension and bradycardia have been observed. Arrhythmia has also occurred.

Respiration

Although respiration is frequently stimulated, severe depression of respiration or apnea may occur following rapid intravenous administration of high doses of ketamine. Laryngospasms and other forms of airway obstruction have occurred during ketamine anesthesia.

Eye

Diplopia and nystagmus have been noted following ketamine administration. It also may cause a slight elevation in intraocular pressure measurement.

Psychological: (See SPECIAL NOTE.)

Neurological

In some patients, enhanced skeletal muscle tone may be manifested by tonic and clonic movements sometimes resembling seizures (see DOSAGE AND ADMINISTRATION section).

Gastrointestinal

Anorexia, nausea and vomiting have been observed; however, this is not usually severe and allows the great majority of patients to take liquids by mouth shortly after regaining consciousness (see DOSAGE AND ADMINISTRATION section).

General: Anaphylaxis

Local pain and exanthema at the injection site have infrequently been reported. Transient erythema and/or morbilliform rash have also been reported.



REPORTS OF SUSPECTED KETAMINE SIDE EFFECTS / ADVERSE REACTIONS

Below is a sample of reports where side effects / adverse reactions may be related to Ketamine. The information is not vetted and should not be considered as verified clinical evidence.

Possible Ketamine side effects / adverse reactions in 60 year old male

Reported by a health professional (non-physician/pharmacist) from France on 2012-01-19

Patient: 60 year old male

Reactions: Anaphylactic Shock, Skin Test Negative

Adverse event resulted in: life threatening event

Suspect drug(s):
Clindamycin
    Dosage: unk
    Indication: Nasal Septal Operation
    Start date: 2010-09-06

Ketamine
    Dosage: unk
    Indication: Nasal Septal Operation
    Start date: 2010-09-06

Solu-Medrol
    Dosage: unk
    Indication: Nasal Septal Operation
    Start date: 2010-09-06

Rocuronium Bromide
    Dosage: unk
    Indication: Nasal Septal Operation
    Start date: 2010-09-06

Sufenta Preservative Free
    Dosage: unk
    Indication: Nasal Septal Operation
    Start date: 2010-09-06

Diprivan
    Dosage: unk
    Indication: Nasal Septal Operation
    Start date: 2010-09-06



Possible Ketamine side effects / adverse reactions in 51 year old male

Reported by a health professional (non-physician/pharmacist) from France on 2012-05-07

Patient: 51 year old male

Reactions: Pancreatitis Acute, Pancreatic Necrosis

Adverse event resulted in: hospitalization

Suspect drug(s):
Cefazolin
    Dosage: 2 g, single
    Start date: 2011-11-08
    End date: 2011-11-08

Solu-Medrol
    Dosage: 80 mg, single
    Start date: 2011-11-08
    End date: 2011-11-08

Diprivan
    Dosage: 300 mg, single
    Indication: General Anaesthesia
    Start date: 2011-11-08
    End date: 2011-11-08

Morphine
    Dosage: unk
    Indication: General Anaesthesia
    Start date: 2011-11-08
    End date: 2011-11-10

Ketamine
    Dosage: 20 mg, single
    Indication: General Anaesthesia
    Start date: 2011-11-08
    End date: 2011-11-08

Midazolam HCL
    Dosage: 1 mg, single
    Indication: General Anaesthesia
    Start date: 2011-11-08
    End date: 2011-11-08

Acetaminophen
    Dosage: 1 g, 4x/day
    Indication: Anaesthesia
    Start date: 2011-11-08
    End date: 2011-11-10

Xanax
    Dosage: 1 mg, single
    Administration route: Oral
    Indication: Anaesthetic Premedication
    Start date: 2011-11-08
    End date: 2011-11-08

Acupan
    Dosage: 20 mg, 1x/day
    Indication: Analgesic Therapy
    Start date: 2011-11-08
    End date: 2011-11-09



See index of all Ketamine side effect reports >>

Drug label data at the top of this Page last updated: 2012-04-23

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