DRUG ABUSE AND DEPENDENCE
Ketamine has been reported being used as a drug of abuse.
Reports suggest that ketamine produces a variety of symptoms including, but
not limited to anxiety, dysphoria, disorientation, insomnia, flashbacks, hallucinations,
and psychotic episodes. Ketamine dependence and tolerance are possible following
prolonged administration. A withdrawal syndrome with psychotic features has
been described following discontinuation of long-term ketamine use. Therefore,
ketamine should be prescribed and administered with caution.
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