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Ketamine (Ketamine Hydrochloride) - Summary

 

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KETAMINE SUMMARY

Ketamine hydrochloride is a nonbarbiturate anesthetic chemically designated (±)-2-(o -Chlorophenyl)-2-(methylamino) cyclohexanone hydrochloride. It is formulated as a slightly acid (pH 3.5 to 5.5) sterile solution for intravenous or intramuscular injection in concentrations containing the equivalent of either 50 or 100 mg ketamine base per milliliter and contains not more than 0.1 mg/mL benzethonium chloride added as a preservative.

Ketamine hydrochloride injection is indicated as the sole anesthetic agent for diagnostic and surgical procedures that do not require skeletal muscle relaxation. Ketamine hydrochloride injection is best suited for short procedures but it can be used, with additional doses, for longer procedures.

Ketamine hydrochloride injection is indicated for the induction of anesthesia prior to the administration of other general anesthetic agents.

Ketamine hydrochloride injection is indicated to supplement low-potency agents, such as nitrous oxide.

Specific areas of application are described in the CLINICAL PHARMACOLOGY section.

KETAMINE NEWS HIGHLIGHTS

Media Articles Related to Ketamine

GE Healthcare Ranks #1 For Anesthesia Service In Md Buyline's Q2 2008 Survey
Source: Pain / Anesthetics News From Medical News Today [2008.09.25]

Springer To Partner With The Canadian Anesthesiologists' Society
Source: Pain / Anesthetics News From Medical News Today [2008.09.27]

USC School Of Dentistry Teachers Hypnosis As An Alternative To Novocain
Source: Dentistry News From Medical News Today [2008.09.24]

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Published Studies Related to Ketamine

A comparison of caudal bupivacaine and ketamine with penile block for paediatric circumcision. [2008.07.24]

Comparison of prophylactic use of midazolam, ketamine, and ketamine plus midazolam for prevention of shivering during regional anaesthesia: a randomized double-blind placebo controlled trial. [2008.07.11]

Effect of ondansetron on the incidence of vomiting associated with ketamine sedation in children: a double-blind, randomized, placebo-controlled trial. [2008.07]

Postoperative ketamine administration decreases morphine consumption in major abdominal surgery: a prospective, randomized, double-blind, controlled study. [2008.06]

Comparison of S-(+)-ketamine- with sufentanil-based anaesthesia for elective coronary artery bypass graft surgery: effect on troponin T levels. [2008.06]

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Clinical Trials Related to Ketamine

Ketamine on Acute Pain in Females and Males [Completed]

Ketamine Improves Post-Thoracotomy Analgesia [Completed]

Ketamine Frequency Treatment for Major Depressive Disorder [Enrolling by invitation]

KETOR: Effects of Peri Operative Administration of Ketamine on Long Term Post Thoracotomy Pain [Completed]

Assessing the Effects of a Nasal Corticosteroid on PMI-150 (Intranasal Ketamine) [Completed]

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Page last updated: 2008-09-27

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