NEWS HIGHLIGHTSMedia Articles Related to Keppra XR (Levetiracetam)
Link Between Epilepsy And Autism Found
Source: Autism News From Medical News Today [2013.05.16]
Adults with epilepsy are more likely to have a greater number of characteristics of autism and Asperger syndrome, according to new research by the University of Bath, England. The finding was discovered by Dr. SallyAnn Wakeford, a PhD student from the University's Department of Psychology, and revealed a previously unknown link between epileptic seizures and the signs of autism in adults...
Brain Cells Cure Epilepsy In Mouse Model
Source: Epilepsy News From Medical News Today [2013.05.08]
UCSF scientists controlled seizures in epileptic mice with a one-time transplantation of medial ganglionic eminence (MGE) cells, which inhibit signaling in overactive nerve circuits, into the hippocampus, a brain region associated with seizures, as well as with learning and memory...
Model Cell System Offers Insights Into Epilepsy, Schizophrenia, Other Neuropsych Disorders
Source: Autism News From Medical News Today [2013.05.06]
Medical researchers have manipulated human stem cells into producing types of brain cells known to play important roles in neurodevelopmental disorders such as epilepsy, schizophrenia and autism...
Implanted Device Predicts Epilepsy Seizures In Humans
Source: Epilepsy News From Medical News Today [2013.05.02]
For the first time, a small device implanted in the brain has accurately predicted the onset of seizures in some adults who have epilepsy that doesn't respond to drugs, according to a small proof-of-concept study published Online First in The Lancet Neurology...
Implanted Device May Predict Epilepsy Seizures, Study Suggests
Source: MedicineNet Seizure Specialty [2013.05.02]
Title: Implanted Device May Predict Epilepsy Seizures, Study Suggests
Category: Health News
Created: 5/2/2013 10:35:00 AM
Last Editorial Review: 5/2/2013 12:00:00 AM
Published Studies Related to Keppra XR (Levetiracetam)
Levetiracetam in the treatment of alcohol dependence: toward the end of the
story? [2012]
that levetiracetam may be efficient in alcohol-related disorder... CONCLUSIONS: By conducting a state-of-the-art randomized-controlled clinical
A double-blind, placebo-controlled trial assessing the efficacy of levetiracetam
extended-release in very heavy drinking alcohol-dependent patients. [2012]
population of very heavy drinkers... CONCLUSIONS: This multisite clinical trial showed no efficacy for levetiracetam
Double-masked, placebo-controlled study of intravenous levetiracetam for the
treatment of status epilepticus and acute repetitive seizures in dogs. [2012]
BACKGROUND: Status epilepticus (SE) and acute repetitive seizures (ARS) are
common canine neurologic emergencies...
A randomized, double-blind, placebo-controlled trial of levetiracetam for dyskinesia in Parkinson's disease. [2011.07]
BACKGROUND: This randomized double blind, placebo-controlled crossover study investigated the antidyskinetic effects of levetiracetam in Parkinson's disease... CONCLUSIONS: Levetiracetam was well tolerated at doses up to 2000 mg per day, but we did not detect any antidyskinetic properties. (c) 2011 Movement Disorder Society. Copyright (c) 2011 Movement Disorder Society.
The anticonvulsant levetiracetam for the treatment of pain in polyneuropathy: a randomized, placebo-controlled, cross-over trial. [2011.07]
Levetiracetam is an anticonvulsant which is assumed to act by modulating neurotransmitter release via binding to the vesicle protein SV2A. This could have an impact on signaling in the nociceptive system, and a pilot study indicated relief of neuropathic pain with levetiracetam. OBJECTIVES: The aim of this study was to test the analgesic effect of levetiracetam in painful polyneuropathy... CONCLUSION: This study indicates that the anticonvulsant levetiracetam has no clinically relevant effect on painful polyneuropathy. Copyright (c) 2010 European Federation of International Association for the Study of Pain Chapters. Published by Elsevier Ltd. All rights reserved.
Clinical Trials Related to Keppra XR (Levetiracetam)
Pharmacokinetic and Safety Trial of Intravenous Levetiracetam in the Treatment of Neonatal Seizures [Recruiting]
Assess the Safety and Efficacy of a Seizure Medication,Levetiracetam(LEV;Keppra),in Neuroscience Intensive Care Unit Patients [Recruiting]
To show that the use of intravenous levitiracetam(LEV;Keppra)for seizure prevention in
patients in the Neuroscience Intensive Care Unit will result in fewer side effects compared
to the current standard of care anticonvulsant and will be at least as effective as the
current standard of care in preventing clinical and sub-clinical seizure activity.
Study of Antiepileptic Drug in Generalised Convulsive Status Epilepticus [Recruiting]
An Open Label Study of L059 (Levetiracetam) in Japanese Epilepsy Subjects With Generalized Tonic-clonic Seizures [Recruiting]
The investigators will provide Levetiracetam treatment to epilepsy subjects in Japan who are
judged to benefit from continued treatment with Levetiracetam by the investigators and who
are willing to continuously receive this drug.
Levetiracetam: The Anti-Convulsant of Choice for Elderly Patients With Dementia [Recruiting]
Elderly persons with dementia are at risk for seizures, however, traditional anticonvulsants
are poorly tolerated in this population. Our goal is to examine Levetiracetam (Keppra) in
elderly dementia patients with seizures. While it has been established that Keppra controls
seizures in this age group, it is important to demonstrate that treatment with Keppra would
not affect cognitive abilities in this large population of patients . As this population is
already cognitively impaired, the best choice of anticonvulsant would be one that does not
further compromise their cognitive abilities. Keppra is an excellent anticonvulsant agent
in the elderly for a variety of reasons, including safety, favorable side effect profile,
lack of interaction with other drugs, and efficacy. Our retrospective pilot data suggests
that cognition is not negatively affected by Keppra. The current prospective study will
assess the cognitive abilities of persons with cognitive impairment at baseline and at weeks
4 and 12. The overall objective is to determine the cognitive tolerability of Keppra for
seizures in elderly cognitively impaired patients.
Reports of Suspected Keppra XR (Levetiracetam) Side Effects
Convulsion (23),
Foetal Exposure During Pregnancy (19),
Pregnancy (16),
Upper Respiratory Tract Infection (10),
Premature Baby (10),
Death (6),
Dyspepsia (6),
Inappropriate Schedule of Drug Administration (6),
Rash (6),
Cerebrovascular Accident (6), more >>
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