Kaletra (Lopinavir / Ritonavir) - Summary

KALETRA SUMMARY

KALETRA®
(lopinavir/ritonavir) capsules
(lopinavir/ritonavir) oral solution

KALETRA (lopinavir/ritonavir) is a co-formulation of lopinavir and ritonavir. Lopinavir is an inhibitor of the HIV protease. As co-formulated in KALETRA, ritonavir inhibits the CYP3A-mediated metabolism of lopinavir, thereby providing increased plasma levels of lopinavir.

KALETRA is indicated in combination with other antiretroviral agents for the treatment of HIV-infection.

KALETRA NEWS HIGHLIGHTS

Media Articles Related to Kaletra (Lopinavir / Ritonavir)

lopinavir and ritonavir, Kaletra
Source: MedicineNet atazanavir Specialty [2005.10.16]

Herpes Suppression May Not Prevent HIV Infection
Source: MedicineNet Genital Herpes In Women Specialty [2008.06.20]

HIV's Genetic 'Flight Plan' Filed
Source: MedPage Today Infectious Disease [2008.10.02]

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Published Studies Related to Kaletra (Lopinavir / Ritonavir)

Absence of HIV-1 shedding in male genital tract after 1 year of first-line lopinavir/ritonavir alone or in combination with zidovudine/lamivudine. [2008.06]

Long-term (4 years) efficacy of lopinavir/ritonavir monotherapy for maintenance of HIV suppression. [2008.06]

Lopinavir/ritonavir monotherapy or plus zidovudine and lamivudine in antiretroviral-naive HIV-infected patients. [2008.01.30]

Induction therapy with trizivir plus efavirenz or lopinavir/ritonavir followed by trizivir alone in naive HIV-1-infected adults. [2008.01.30]

Seven-year efficacy of a lopinavir/ritonavir-based regimen in antiretroviral-naive HIV-1-infected patients. [2008.01]

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Clinical Trials Related to Kaletra (Lopinavir / Ritonavir)

A Comparison Study of Kaletra Soft-Gel Capsules and Kaletra Tablets in an African American Cohort [Completed]

Efficacy of Simplified Two Drug Kaletra Regimen vs. Kaletra Triple Drug Standard of Care Regimen in Treatment naïve HIV Infected Patients [Completed]

A Multicenter Study to Assess the Tolerability of Once Daily Lopinavir/Ritonavir (LPV/r) Liquid Versus Capsules [Not yet recruiting]

Safety and Efficacy of Kaletra in ARV Therapy Experienced Patients [Terminated]

Lopinavir/Ritonavir Monotherapy vs Standard HAART in HIV/HCV Coinfected ARV Naive Patients Starting Treatment With Anti HCV Therapy [Recruiting]

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