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Isuprel (Isoproterenol Hydrochloride Intracardiac) - Summary

 


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ISUPREL SUMMARY

ISUPREL®
Isoproterenol Hydrochloride
Injection, USP

Isoproterenol hydrochloride is 3,4-Dihydroxy-α-[(isopropylamino)methyl] benzyl alcohol hydrochloride, a synthetic sympathomimetic amine that is structurally related to epinephrine but acts almost exclusively on beta receptors.

Isoproterenol hydrochloride injection is indicated:

  • For mild or transient episodes of heart block that do not require electric shock or pacemaker therapy.

  • For serious episodes of heart block and Adams-Stokes attacks (except when caused by ventricular tachycardia or fibrillation). (See CONTRAINDICATIONS.)

  • For use in cardiac arrest until electric shock or pacemaker therapy, the treatments of choice, is available. (See CONTRAINDICATIONS.)

  • For bronchospasm occurring during anesthesia.

  • As an adjunct to fluid and electrolyte replacement therapy and the use of other drugs and procedures in the treatment of hypovolemic and septic shock, low cardiac output (hypoperfusion) states, congestive heart failure, and cardiogenic shock. (See WARNINGS.)


See all Isuprel indications & dosage >>

ISUPREL NEWS HIGHLIGHTS

Published Studies Related to Isuprel (Isoproterenol Intracardiac)

Bolus isoproterenol infusions provide a reliable method for assessing interoceptive awareness. [2008.09.27]

Head-up tilt table testing in syncope: safety and efficiency of isosorbide versus isoproterenol in pediatric population. [2008.09]

L-arginine inhibits isoproterenol-induced cardiac hypertrophy through nitric oxide and polyamine pathways. [2008.08]

Effect of the endothelin receptor antagonist CPU0213, and its modulation by rifampin, on cardiac and vascular tissue following chronic isoproterenol treatment. [2008.07]

Effects of isoproterenol treatment for 7 days on inflammatory mediators in the rat aorta. [2008.07]

more >>

Clinical Trials Related to Isuprel (Isoproterenol Intracardiac)

Vascular Response to Isoproterenol and β2 Adrenergic Receptor Polymorphisms [Completed]

Isoproterenol Challenge to Detect Arrhythmogenic Right Ventricular Cardiomyopathy [Completed]

Association of Beta-2 Adrenergic Agonist and Corticosteroid Injection in the Treatment of Lipomas [Recruiting]

Pharmacological Modulation of the Intrarenal Pressure During Endourological Procedures in the Upper Urinary Tract [Completed]

Retrograde Intrarenal Stone Surgery - A Method of Treating the ESWL Resistant Kidney Stone [Active, not recruiting]

more >>

Page last updated: 2008-11-03

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