Ismotic (Isosorbide) - Indications and Dosage

INDICATIONS AND USAGE

For the short-term reduction of intraocular pressure. May be used prior to and after intraocular surgery. May be used to interrupt an acute attack of glaucoma.

DOSAGE AND ADMINISTRATION

The recommended initial dose of isosorbide is 1.5 gm/kg body weight (equivalent to 1.5 mL /lb. of body weight). The onset of action is usually within 30 minutes while the maximum effect is expected at 1 to 1 1/2 hours. The useful dose range is 1 to 3 gm/kg body weight and the drug effect will persist up to 5 to 6 hours. Use two to four times a day as indicated. Palatability may be improved if the medication is poured over cracked ice and sipped.

RECOMMENDED DOSAGES ARE:

POUNDS	MILLILITERS	POUNDS	MILLILITERS
100	150	155	235
105	155	160	240
110	165	165	250
115	170	170	255
120	180	175	265
125	190	180	270
130	195	185	280
135	205	190	285
140	210	195	295
145	220	200	300
150	225

HOW SUPPLIED

Disposable plastic bottles of 220 mL (100 gm of isosorbide/220 mL) for oral use only.

NDC 0065-0034-08

Storage: Store at 15°-30°C (59°-86°F).

CAUTION: Federal (USA) law prohibits dispensing without prescription.

Mfd. for : Alcon Laboratories, Inc.

Fort Worth, Texas 76134 USA

Mfd. by: ALCON (Puerto Rico) INC.

Humacao, Puerto Rico 00791 USA

July 1997      Printed in USA

249165-0797