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Inversine (Mecamylamine Hydrochloride) - Published Studies

 
 



Inversine Related Published Studies

Well-designed clinical trials related to Inversine (Mecamylamine)

Effects of the nicotinic receptor antagonist mecamylamine on ad-lib smoking behavior, topography, and nicotine levels in smokers with and without schizophrenia: a preliminary study. [2009.12]

Effects of acute ultra-low dose mecamylamine on cognition in adult attention-deficit/hyperactivity disorder (ADHD). [2009.06]

A randomized, controlled trial to assess the efficacy and safety of a transdermal delivery system of nicotine/mecamylamine in cigarette smokers. [2007.05]

A randomized, controlled trial to assess the efficacy and safety of a transdermal delivery system of nicotine/mecamylamine in cigarette smokers. [2007.03.01]

The influence of mecamylamine on trigeminal and olfactory chemoreception of nicotine. [2006.02]

Mecamylamine and ethanol preference in healthy volunteers. [2005.01]

Mecamylamine attenuates the subjective stimulant-like effects of alcohol in social drinkers. [2003.05]

Multicenter, double-blind, placebo-controlled study of mecamylamine monotherapy for Tourette's disorder. [2001.09]

Acute effects of nicotine and mecamylamine on tobacco withdrawal symptoms, cigarette reward and ad lib smoking. [2001.02]

A nicotine antagonist, mecamylamine, reduces cue-induced cocaine craving in cocaine-dependent subjects. [1999.03]

Nicotine-mecamylamine treatment for smoking cessation: the role of pre-cessation therapy. [1998.08]

Mecamylamine does not precipitate withdrawal in cigarette smokers. [1996.10]

Mecamylamine combined with nicotine skin patch facilitates smoking cessation beyond nicotine patch treatment alone. [1994.07]

Age-related effects of the nicotinic antagonist mecamylamine on cognition and behavior. [1994.04]

Mecamylamine reduces some EEG effects of nicotine chewing gum in humans. [1988.05]

Well-designed clinical trials possibly related to Inversine (Mecamylamine)

Cognitive performance and cholinergic transmission: influence of muscarinic and nicotinic receptor blockade. [2010.11]

Impaired off-line consolidation of motor memories after combined blockade of cholinergic receptors during REM sleep-rich sleep. [2009.06]

Estrogen treatment effects on anticholinergic-induced cognitive dysfunction in normal postmenopausal women. [2006.09]

Muscarinic and nicotinic receptors synergistically modulate working memory and attention in humans. [2006.04]

Precessation treatment with nicotine skin patch facilitates smoking cessation. [2006.02]

Evidence for synergistic modulation of early information processing by nicotinic and muscarinic receptors in humans. [2004.10]

Extinguishing the rewarding value of smoke cues: pharmacological and behavioral treatments. [2004.06]

The effects of transdermal nicotine on inspection time. [2002.04]

Acute nicotinic blockade produces cognitive impairment in normal humans. [1992]

Other research related to Inversine (Mecamylamine)

Sexually diergic hypothalamic-pituitary-adrenal (HPA) responses to single-dose nicotine, continuous nicotine infusion, and nicotine withdrawal by mecamylamine in rats. [2011.05.30]

Nicotine's enhancing effects on responding maintained by conditioned reinforcers are reduced by pretreatment with mecamylamine, but not hexamethonium, in rats. [2010.08]

Topical mecamylamine for diabetic macular edema. [2010.05]

Effects of varenicline and mecamylamine on the acquisition, expression, and reinstatement of nicotine-conditioned place preference by drug priming in rats. [2010.04]

Inhibitory influence of mecamylamine on ethanol withdrawal-induced symptoms in C57BL/6J mice. [2010.03]

Mecamylamine - a nicotinic acetylcholine receptor antagonist with potential for the treatment of neuropsychiatric disorders. [2009.11]

The influence of mecamylamine on ethanol and sucrose self-administration. [2009.09]

Modulation of ethanol drinking-in-the-dark by mecamylamine and nicotinic acetylcholine receptor agonists in C57BL/6J mice. [2009.07]

Antidepressant-like effects of nicotine and mecamylamine in the mouse forced swim and tail suspension tests: role of strain, test and sex. [2009.05]

Effects of mecamylamine on alcohol consumption and preference in male C57BL/6J mice. [2009]

Interactions between age and the aversive effects of nicotine withdrawal under mecamylamine-precipitated and spontaneous conditions in male Wistar rats. [2008.06]

Mecamylamine suppresses Basal and nicotine-stimulated choroidal neovascularization. [2008.04]

The nicotinic acetylcholine receptor antagonist mecamylamine prevents escalation of cocaine self-administration in rats with extended daily access. [2007.09]

Effects of acute abstinence, reinstatement, and mecamylamine on biochemical and behavioral measures of cigarette smoking in schizophrenia. [2007.03]

Cholinergic modulation of Pavlovian fear conditioning in rats: differential effects of intrahippocampal infusion of mecamylamine and methyllycaconitine. [2007.03]

Mecamylamine attenuates cue-induced reinstatement of nicotine-seeking behavior in rats. [2007.03]

Low-dose mecamylamine improves learning of rats in the radial-arm maze repeated acquisition procedure. [2006.07]

Intravenous nicotine self-administration in rats: effects of mecamylamine, hexamethonium and naloxone. [2006.03]

Mecamylamine (Targacept). [2006.03]

Dynorphin A (2-13) improves mecamylamine-induced learning impairment accompanied by reversal of reductions in acetylcholine release in rats. [2006.02]

A placebo controlled, double-blind study of mecamylamine treatment for cocaine dependence in patients enrolled in an opiate replacement program. [2006]

Mecamylamine attenuates ephedrine-induced hyperactivity in rats. [2005.05]

Mecamylamine moderates cue-induced emotional responses in smokers. [2005.05]

Blockade of the expression of mecamylamine-precipitated nicotine withdrawal by calcium channel antagonists. [2005.05]

Mecamylamine acutely increases human intravenous nicotine self-administration. [2003.09]

Effects of puerarin on scopolamine-, mecamylamine-, p-chloroamphetamine- and dizocilpine-induced inhibitory avoidance performance impairment in rats. [2002.10]

Mecamylamine decreases accumbal dopamine output in mice treated chronically with nicotine. [2002.09.27]

Mecamylamine (Inversine): an old antihypertensive with new research directions. [2002.07]

Open field habituation learning is improved by nicotine and attenuated by mecamylamine administered posttrial into the nucleus accumbens. [2002.05]

Modulation of kappa-opioidergic systems on mecamylamine-precipitated nicotine-withdrawal aversion in rats. [2002.04.26]

Nicotine induced seizures blocked by mecamylamine and its stereoisomers. [2001.10.19]

Mecamylamine effects on haloperidol-induced catalepsy and defecation. [2001.07]

Corticosterone-attenuating and anxiolytic properties of mecamylamine in the rat. [2001.04]

The nicotinic antagonist mecamylamine preferentially inhibits cocaine vs. food self-administration in rats. [2000.12]

Comorbid bipolar disorder in Tourette's syndrome responds to the nicotinic receptor antagonist mecamylamine (Inversine). [2000.11.15]

Modulation of opioidergic system on mecamylamine-precipitated nicotine-withdrawal aversion in rats. [2000.07]

Nicotine-mecamylamine interactions. [2000.07]

Mecamylamine blockade of both positive and negative effects of IV nicotine in human volunteers. [2000.07]

Mecamylamine in Tourette's syndrome: a two-year retrospective case study. [2000.06]

Effects of the nicotinic antagonist mecamylamine on inspection time. [2000.05]

Mecamylamine (a nicotine antagonist) for smoking cessation. [2000]

Behavioral and biochemical manifestations of mecamylamine-precipitated nicotine withdrawal in the rat: role of nicotinic receptors in the ventral tegmental area. [1999.10]

Mecamylamine-precipitated nicotine-withdrawal aversion in Lewis and Fischer 344 inbred rat strains. [1999.03.19]

Effects of nicotine and mecamylamine microinjections into the nucleus accumbens on ethanol and sucrose self-administration. [1998.09]

Reduced dopamine output in the nucleus accumbens but not in the medial prefrontal cortex in rats displaying a mecamylamine-precipitated nicotine withdrawal syndrome. [1998.01.01]

Accumbal dopamine overflow after ethanol: localization of the antagonizing effect of mecamylamine. [1997.09.10]

Attenuation of mecamylamine-precipitated nicotine-withdrawal aversion by the 5-HT3 receptor antagonist ondansetron. [1997]

Mecamylamine-induced impairment of acquisition and retrieval of olfactory conditioning in the honeybee. [1996.11]

Mecamylamine-precipitated nicotine-withdrawal aversion in rats. [1996.10.31]

The nicotinic antagonist mecamylamine precipitates nicotine abstinence syndrome in the rat. [1994.06]

Effects of systemic and intracerebroventricular administration of mecamylamine, a nicotinic cholinergic antagonist, on spatial memory in rats. [1992]

Mecamylamine increases nicotine preference and attenuates nicotine discrimination. [1989.04]

Other possibly related research studies

Rhesus monkey alpha7 nicotinic acetylcholine receptors: comparisons to human alpha7 receptors expressed in Xenopus oocytes. [2005.11.07]

Functional central nicotinic acetylcholine receptor antagonism by systemic administration of Tinuvin 770 (BTMPS). [2005.04]

Effects of cigarette smoking on spatial working memory and attentional deficits in schizophrenia: involvement of nicotinic receptor mechanisms. [2005.06]

Muscarinic and nicotinic receptor modulation of object and spatial n-back working memory in humans. [2005.07]

Is antagonism of alpha3beta4 nicotinic receptors a strategy to reduce morphine dependence? [2005.04.25]

Increased expression of L-type high voltage-gated calcium channel alpha1 and alpha2/delta subunits in mouse brain after chronic nicotine administration. [2005.04.27]

Enhancement of PAI-1 mRNA in cardiovascular cells after kainate injection is mediated through the sympathetic nervous system. [2005.05]

Smoking cue reactivity in schizophrenia: effects of a nicotinic receptor antagonist. [2005.04.01]

Antinociceptive effects of choline against acute and inflammatory pain. [2005]

[ABC of smoking cessation. Bupropion and other drugs in non-nicotine therapy] [2004]

Investigation of the mechanisms involved in the central effects of glucagon-like peptide-1 on ethanol-induced gastric mucosal lesions. [2005.05.15]

ABT-594 (a nicotinic acetylcholine agonist): anti-allodynia in a rat chemotherapy-induced pain model. [2005.02.10]

Effects of nicotinic and NMDA receptor channel blockers on intravenous cocaine and nicotine self-administration in mice. [2005.03]

Differential effects of nicotine and smoke condensate on bone cell metabolic activity. [2005.01]

Delta9-tetrahydrocannabinol decreases somatic and motivational manifestations of nicotine withdrawal in mice. [2004.11]

Nicotine attenuates relapse to methamphetamine-seeking behavior (craving) in rats. [2004.10]

Influence of nicotine on brain reward systems: study of intracranial self-stimulation. [2004.10]

Possible pharmacotherapy of the opioid kappa receptor agonist for drug dependence. [2004.10]

Decreased signs of nicotine withdrawal in mice null for the beta4 nicotinic acetylcholine receptor subunit. [2004.11.10]

High-affinity nicotinic acetylcholine receptors are required for antidepressant effects of amitriptyline on behavior and hippocampal cell proliferation. [2004.11.01]

Antinociceptive and gastroprotective effects of inhaled and orally administered Lavandula hybrida Reverchon "Grosso" essential oil. [2004.11.26]

CDP-choline increases plasma ACTH and potentiates the stimulated release of GH, TSH and LH: the cholinergic involvement. [2004.10]

Local perfusion of nicotine differentially modulates somatodendritic dopamine release in the rat ventral tegmental area after nicotine preexposure. [2004.09]

Nicotine physical dependence and tolerance in the mouse following chronic oral administration. [2005.03]

Differential effects of M1 muscarinic receptor blockade and nicotinic receptor blockade in the dorsomedial striatum on response reversal learning. [2004.09.23]

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