Published Studies Related to Infed (Iron Dextran)
A randomized controlled trial comparing intravenous ferric carboxymaltose with oral iron for treatment of iron deficiency anaemia of non-dialysis-dependent chronic kidney disease patients. [2011.05]
BACKGROUND: Iron deficiency is a common cause of anaemia and hyporesponsiveness to erythropoiesis-stimulating agents (ESAs) in non-dialysis-dependent chronic kidney disease (ND-CKD) patients. Current intravenous iron agents cannot be administered in a single high dose because of adverse effects. Ferric carboxymaltose, a non-dextran parenteral iron preparation, can be rapidly administered in high doses... CONCLUSIONS: We conclude that 1000 mg ferric carboxymaltose can be rapidly administered, is more effective and is better tolerated than oral iron for treatment of iron deficiency in ND-CKD patients.
Total infusion of low molecular weight iron-dextran for treating postpartum anemia. 
AIM: 135 puerperal women with iron deficiency anemia participated in our prospective randomized controlled trial in order to investigate alternative treatments to blood transfusion for anemia... CONCLUSION: It seems that total iron-dextran infusion is a safe and rapid therapy of iron-deficiency postpartum anemia increases the Hb level more rapidly than oral ferrous sulfate, and it also appears to replenish iron stores more rapidly.
Lipid peroxidation products formation with various intravenous iron preparations in chronic kidney disease. 
The role of intravenous iron in contributing to oxidative stress and endothelial dysfunction in chronic kidney disease (CKD) is debatable. The present study assessed differences in fasting plasma malondialdehyde (pMDA) levels 30 minutes before and after intravenous infusion of low molecular weight iron dextran (ID) (n = 19), iron-sucrose (IS) (n = 20), and sodium ferrigluconate complex (SFGC) (n = 20) in stage 3 and 4 CKD patients...
Iron sucrose causes greater proteinuria than ferric gluconate in non-dialysis chronic kidney disease. [2007.09]
Non-dextran intravenous (i.v.) iron preparations seem to differentially affect proteinuria in patients with chronic kidney disease. To study effects of ferric gluconate and iron sucrose on proteinuria, we conducted a crossover trial in 12 patients with stage 3-4 chronic kidney disease...
Iron therapy in the pediatric hemodialysis population. [2004.06]
Iron therapy maintains iron stores and optimizes the response to recombinant human erythropoietin (r-HuEPO) in patients with end-stage renal failure. Information is limited, however, regarding the preferential route of iron administration in pediatric patients receiving hemodialysis.therapy allowed for a significant improvement in iron stores.
Clinical Trials Related to Infed (Iron Dextran)
Safety Assessment of Iron Sucrose (Venofer) in Patients With Chronic Kidney Disease Who Cannot Tolerate Ferumoxytol (Feraheme) or Iron Dextran (INFed or Dexferrum) [Recruiting]
The objective of this study is to assess the safety and tolerability of Venofer in patients
with chronic kidney disease who cannot tolerate Ferumoxytol (Feraheme) or intravenous iron
containing a dextran (INFed or Dexferrum).
Intravenous Ferric Carboxymaltose (FCM) Versus IV Iron Sucrose or IV Iron Dextran in Treating Iron Deficiency Anemia in Women [Recruiting]
The purpose of this study is to compare safety and the oxidative stress potential of two
doses of an investigational IV iron, ferric carboxymaltose (FCM), compared to an equal
single dose of IV iron sucrose or IV iron dextran in the treatment of Iron Deficiency Anemia
(IDA) in female subjects.
Trial Comparing the Safety of Two Different Intravenous Iron Formulations [Recruiting]
The purpose of this trial is to compare the safety profile using equal doses of intravenous
iron dextran versus iron sucrose. The researchers hypothesize that significantly more
patients receiving intravenous iron dextran (using the current intermediate molecular weight
product) will have severe adverse outcomes than patients receiving iron sucrose in the adult
non-hemodialysis outpatient population. Secondly, since these severe reactions may require
additional nursing time and physician interventions that may negate any cost advantage of
iron dextran, the researchers hypothesize that iron sucrose will be more cost-effective than
Validation Study of RA-INF-Dx, a Multigene Molecular Test Used to Predict Non-Response to INfliximab Therapy [Recruiting]
Study Design & Objectives:
Multi-centre, non-interventional, open-label, non-comparative, prospective cohort study with
a clinical follow-up between 12 and 14 weeks.
To determine the performances of the RA-INF-Dx blood test intended to aid in the
identification of patients with rheumatoid arthritis who are unlikely to show an initial
response to infliximab and methotrexate combination therapy evaluated according to EULAR
Ancillary study objective:
To constitute a biocollection of samples associated with all clinical and biological data
collected at inclusion and at the evaluation visit.
Safety and Tolerability of Ferric Carboxymaltose (FCM) Versus Iron Dextran in Treating Iron Deficiency Anemia [Recruiting]
The objective of this study is to evaluate the safety of FCM in patients with anemia who are
not dialysis dependent.
Reports of Suspected Infed (Iron Dextran) Side Effects
Back Pain (4),
Throat Irritation (4),
Anaphylactic Reaction (3),
Feeling Hot (3),
Blood Pressure Increased (3),
Heart Rate Increased (3),
Erythema (2), more >>