Infanrix (Diphtheria Toxoid / Tetanus Toxoid / Acellular Pertussis Vaccine) - Summary

INFANRIX SUMMARY

INFANRIX (Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine Adsorbed) is a noninfectious, sterile combination of diphtheria and tetanus toxoids and 3 pertussis antigens [inactivated pertussis toxin (PT), filamentous hemagglutinin (FHA), and pertactin (69 kiloDalton outer membrane protein)] adsorbed onto aluminum hydroxide. INFANRIX is intended for intramuscular injection only.

INFANRIX is indicated for active immunization against diphtheria, tetanus, and pertussis (whooping cough) as a 5-dose series in infants and children 6 weeks to 7 years of age (prior to seventh birthday). Because of the substantial risks of complications from pertussis disease in infants, completion of the primary series of 3 doses of vaccine early in life is strongly recommended (see DOSAGE AND ADMINISTRATION). ¹ INFANRIX should not be administered to any infant before the age of 6 weeks, or to individuals 7 years of age or older.

When passive protection against tetanus or diphtheria is required, Tetanus Immune Globulin or Diphtheria Antitoxin, respectively, should be administered at separate sites. ¹

As with any vaccine, INFANRIX may not protect 100% of individuals receiving the vaccine, and is not recommended for treatment of actual infections.

INFANRIX NEWS HIGHLIGHTS

Media Articles Related to Infanrix (Diphtheria / Tetanus / Pertussis)

diphtheria-tetanus-pertussis vaccine pediatric-injection, Daptacel, Infanrix, Tripedia
Source: MedicineNet Pertussis Specialty [2005.03.02]

diphtheria/tetanus/pertussis vaccine-injection
Source: MedicineNet Pertussis Specialty [2005.03.02]

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Published Studies Related to Infanrix (Diphtheria / Tetanus / Pertussis)

Absence of an increase in cardiorespiratory events after diphtheria-tetanus-acellular pertussis immunization in preterm infants: a randomized, multicenter study. [2008.05]

Diphtheria-tetanus-acellular pertussis and inactivated poliovirus vaccines given separately or combined for booster dosing at 4-6 years of age. [2008.04]

One-year post-primary antibody persistence and booster immune response to a fully liquid five-component acellular pertussis, diphtheria, tetanus, inactivated poliomyelitis, Haemophilus influenzae type b conjugate vaccine. [2007.11]

Primary vaccination of adults with reduced antigen-content diphtheria-tetanus-acellular pertussis or dTpa-inactivated poliovirus vaccines compared to diphtheria-tetanus-toxoid vaccines. [2007.11]

Quality of the Haemophilus influenzae type b (Hib) antibody response induced by diphtheria-tetanus-acellular pertussis/Hib combination vaccines. [2007.10]

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Clinical Trials Related to Infanrix (Diphtheria / Tetanus / Pertussis)

Immunogenicity, Antibody Persistence and Safety of GSK Biologicals' DTPa (INFANRIX) and dTpa (BOOSTRIX) Vaccines. [Completed]

Comparison of a DTaP-IPV-HB-PRP~T Combined Vaccine to Infanrixâ„¢-Hexa, When Administered With Prevnar® in Thai Infants [Active, not recruiting]

Study to Compare Pediacel® to Infanrix®-IPV+Hib When Both Are Co-Administered With Prevenar® in Infants and Toddlers [Active, not recruiting]

Safety and Immunogenicity of a New Serum-Free DTaP-IPVvero Combination Vaccine [Completed]

Study of the Safety, Immunogenicity and Lot Comparability of DAPTACEL When Administered With Other Recommended Vaccine [Completed]

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