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Inderal (Propranolol Hydrochloride) - Side Effects and Adverse Reactions

 
 



ADVERSE REACTIONS

The following adverse events were observed and have been reported in patients using propranolol.

Cardiovascular: Bradycardia; congestive heart failure; intensification of AV block; hypotension; paresthesia of hands; thrombocytopenic purpura; arterial insufficiency, usually of the Raynaud type.

Central Nervous System: Light-headedness, mental depression manifested by insomnia, lassitude, weakness, fatigue; catatonia; visual disturbances; hallucinations; vivid dreams; an acute reversible syndrome characterized by disorientation for time and place, short-term memory loss, emotional lability, slightly clouded sensorium, and decreased performance on neuropsychometrics. For immediate-release formulations, fatigue, lethargy, and vivid dreams appear dose-related.

Gastrointestinal: Nausea, vomiting, epigastric distress, abdominal cramping, diarrhea, constipation, mesenteric arterial thrombosis, ischemic colitis.

Allergic: Hypersensitivity reactions, including anaphylactic/anaphylactoid reactions, pharyngitis and agranulocytosis; erythematous rash, fever combined with aching and sore throat; laryngospasm, and respiratory distress.

Respiratory: Bronchospasm.

Hematologic: Agranulocytosis, nonthrombocytopenic purpura, thrombocytopenic purpura.

Autoimmune: Systemic lupus erythematosus (SLE).

Skin and mucous membranes: Stevens-Johnson Syndrome, toxic epidermal necrolysis, dry eyes, exfoliative dermatitis, erythema multiforme, urticaria, alopecia, SLE-like reactions, and psoriasiform rashes. Oculomucocutaneous syndrome involving the skin, serous membranes and conjunctivae reported for a beta blocker (practolol) have not been associated with propranolol.

Genitourinary: Male impotence; Peyronie's disease.



REPORTS OF SUSPECTED INDERAL SIDE EFFECTS / ADVERSE REACTIONS

Below is a sample of reports where side effects / adverse reactions may be related to Inderal. The information is not vetted and should not be considered as verified clinical evidence.

Possible Inderal side effects / adverse reactions in 64 year old male

Reported by a health professional (non-physician/pharmacist) from Japan on 2011-10-07

Patient: 64 year old male

Reactions: Liver Carcinoma Ruptured

Adverse event resulted in: death

Suspect drug(s):
Inderal
    Indication: Portal Hypertension

Inderal
    Dosage: 10 mg, 3x/day
    Administration route: Oral
    Indication: Small Intestinal Haemorrhage
    Start date: 2011-08-17
    End date: 2011-09-07



Possible Inderal side effects / adverse reactions in 64 year old male

Reported by a health professional (non-physician/pharmacist) from Japan on 2011-10-13

Patient: 64 year old male

Reactions: Liver Carcinoma Ruptured

Adverse event resulted in: death

Suspect drug(s):
Inderal
    Dosage: 10 mg, 3x/day
    Administration route: Oral
    Indication: Small Intestinal Haemorrhage
    Start date: 2011-08-17
    End date: 2011-09-07

Inderal
    Indication: Portal Hypertension

Other drugs received by patient: Diart; Aldactone; Aminoleban EN; Monilac



Possible Inderal side effects / adverse reactions in 31 year old female

Reported by a physician from Switzerland on 2011-10-17

Patient: 31 year old female

Reactions: Therapeutic Response Increased, Hypotension, Drug Interaction, Asthenia

Suspect drug(s):
Inderal
    Indication: Alcohol Poisoning

Inderal
    Administration route: Oral
    Indication: General Physical Health Deterioration
    End date: 2010-09-30

Other drugs received by patient possibly interacting with the suspect drug:
Effexor
    Indication: Depression
    End date: 2010-09-23

Effexor
    Administration route: Oral
    Start date: 2010-09-24
    End date: 2010-09-28

Metoclopramide Hydrochloride
    Administration route: Oral
    Indication: General Physical Health Deterioration
    Start date: 2010-09-24
    End date: 2010-09-30

Effexor
    Administration route: Oral
    Start date: 2010-09-29

Other drugs received by patient: Nexium; Oxazepam; Fluticasone Propionate/salmeterol



See index of all Inderal side effect reports >>

Drug label data at the top of this Page last updated: 2008-01-24

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