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Inderal (Propranolol Hydrochloride) - Side Effects and Adverse Reactions

 



ADVERSE REACTIONS

The following adverse events were observed and have been reported in patients using propranolol.

Cardiovascular: Bradycardia; congestive heart failure; intensification of AV block; hypotension; paresthesia of hands; thrombocytopenic purpura; arterial insufficiency, usually of the Raynaud type.

Central Nervous System: Light-headedness, mental depression manifested by insomnia, lassitude, weakness, fatigue; catatonia; visual disturbances; hallucinations; vivid dreams; an acute reversible syndrome characterized by disorientation for time and place, short-term memory loss, emotional lability, slightly clouded sensorium, and decreased performance on neuropsychometrics. For immediate-release formulations, fatigue, lethargy, and vivid dreams appear dose-related.

Gastrointestinal: Nausea, vomiting, epigastric distress, abdominal cramping, diarrhea, constipation, mesenteric arterial thrombosis, ischemic colitis.

Allergic: Hypersensitivity reactions, including anaphylactic/anaphylactoid reactions, pharyngitis and agranulocytosis; erythematous rash, fever combined with aching and sore throat; laryngospasm, and respiratory distress.

Respiratory: Bronchospasm.

Hematologic: Agranulocytosis, nonthrombocytopenic purpura, thrombocytopenic purpura.

Autoimmune: Systemic lupus erythematosus (SLE).

Skin and mucous membranes: Stevens-Johnson Syndrome, toxic epidermal necrolysis, dry eyes, exfoliative dermatitis, erythema multiforme, urticaria, alopecia, SLE-like reactions, and psoriasiform rashes. Oculomucocutaneous syndrome involving the skin, serous membranes and conjunctivae reported for a beta blocker (practolol) have not been associated with propranolol.

Genitourinary: Male impotence; Peyronie's disease.



REPORTS OF SIDE EFFECTS / ADVERSE REACTIONS RELATED TO INDERAL

Below is a sample of reports where side effects / adverse reactions may be related to Inderal. The information is not vetted and should not be cosidered as verified clinical evidence.

Possible Inderal side effects / adverse reactions in 28 year old male

Reported by a consumer/non-health professional from United States on 2009-04-17

Patient: 28 year old male weighing 104.3 kg (229.5 pounds)

Reactions: Akathisia, Confusional State, Flat Affect, Nightmare, Restlessness, Impaired Work Ability, Suicidal Ideation, Anxiety, Thinking Abnormal, Diarrhoea, Sleep Disorder, Depression, Feeling Abnormal, Asthenia

Suspect drug(s):
Abilify
    Dosage: see image
    Indication: Bipolar II Disorder
    Start date: 2008-11-12
    End date: 2009-03-06

Abilify

Abilify

Inderal



Possible Inderal side effects / adverse reactions in 60 year old female

Reported by a health professional (non-physician/pharmacist) from Japan on 2009-04-27

Patient: 60 year old female weighing 54.0 kg (118.8 pounds)

Reactions: Arteriospasm Coronary

Adverse event resulted in: life threatening event

Suspect drug(s):
Diprivan
    Dosage: induction
    Indication: Anaesthesia
    Start date: 1998-11-29
    End date: 1998-11-29

Diprivan
    Dosage: maintenance
    Start date: 1998-11-29
    End date: 1998-11-29

Inderal
    Indication: Hypotension
    Start date: 1998-11-29
    End date: 1998-11-29

Prostaglandin E1
    Dosage: temp stopped
    Indication: Hypotension
    Start date: 1998-11-29
    End date: 1998-11-29

Prostaglandin E1
    Dosage: re-started 20 mins later
    Start date: 1998-11-29
    End date: 1998-11-29

Other drugs received by patient: Fentanyl; Famotidine; Meperidine HCL; Midazolam HCL; Atropine Sulphate; Vecuronium Bromide; Pethidine Hydrochloride



Possible Inderal side effects / adverse reactions in 77 year old female

Reported by a physician from Japan on 2009-04-29

Patient: 77 year old female

Reactions: Pancytopenia

Suspect drug(s):
Inderal
    Dosage: 20 mg bid

Rabeprazole Sodium



See index of all Inderal side effect reports >>

Drug label data at the top of this Page last updated: 2008-01-24

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