ADVERSE REACTIONS
The following adverse events were observed and have been reported in patients using propranolol.
Cardiovascular: Bradycardia; congestive heart failure; intensification of AV block; hypotension; paresthesia of hands; thrombocytopenic purpura; arterial insufficiency, usually of the Raynaud type.
Central Nervous System: Light-headedness, mental depression manifested by insomnia, lassitude, weakness, fatigue; catatonia; visual disturbances; hallucinations; vivid dreams; an acute reversible syndrome characterized by disorientation for time and place, short-term memory loss, emotional lability, slightly clouded sensorium, and decreased performance on neuropsychometrics. For immediate-release formulations, fatigue, lethargy, and vivid dreams appear dose-related.
Gastrointestinal: Nausea, vomiting, epigastric distress, abdominal cramping, diarrhea, constipation, mesenteric arterial thrombosis, ischemic colitis.
Allergic: Hypersensitivity reactions, including anaphylactic/anaphylactoid reactions, pharyngitis and agranulocytosis; erythematous rash, fever combined with aching and sore throat; laryngospasm, and respiratory distress.
Respiratory: Bronchospasm.
Hematologic: Agranulocytosis, nonthrombocytopenic purpura, thrombocytopenic purpura.
Autoimmune: Systemic lupus erythematosus (SLE).
Skin and mucous membranes: Stevens-Johnson Syndrome, toxic epidermal necrolysis, dry eyes, exfoliative dermatitis, erythema multiforme, urticaria, alopecia, SLE-like reactions, and psoriasiform rashes. Oculomucocutaneous syndrome involving the skin, serous membranes and conjunctivae reported for a beta blocker (practolol) have not been associated with propranolol.
Genitourinary: Male impotence; Peyronie's disease.
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REPORTS OF SUSPECTED INDERAL SIDE EFFECTS / ADVERSE REACTIONS
Below is a sample of reports where side effects / adverse reactions may be related to Inderal. The information is not vetted and should not be considered as verified clinical evidence.
Possible Inderal side effects / adverse reactions in 64 year old male
Reported by a health professional (non-physician/pharmacist) from Japan on 2011-10-07
Patient: 64 year old male
Reactions: Liver Carcinoma Ruptured
Adverse event resulted in: death
Suspect drug(s):
Inderal
Indication: Portal Hypertension
Inderal
Dosage: 10 mg, 3x/day
Administration route: Oral
Indication: Small Intestinal Haemorrhage
Start date: 2011-08-17
End date: 2011-09-07
Possible Inderal side effects / adverse reactions in 64 year old male
Reported by a health professional (non-physician/pharmacist) from Japan on 2011-10-13
Patient: 64 year old male
Reactions: Liver Carcinoma Ruptured
Adverse event resulted in: death
Suspect drug(s):
Inderal
Dosage: 10 mg, 3x/day
Administration route: Oral
Indication: Small Intestinal Haemorrhage
Start date: 2011-08-17
End date: 2011-09-07
Inderal
Indication: Portal Hypertension
Other drugs received by patient: Diart; Aldactone; Aminoleban EN; Monilac
Possible Inderal side effects / adverse reactions in 31 year old female
Reported by a physician from Switzerland on 2011-10-17
Patient: 31 year old female
Reactions: Therapeutic Response Increased, Hypotension, Drug Interaction, Asthenia
Suspect drug(s):
Inderal
Indication: Alcohol Poisoning
Inderal
Administration route: Oral
Indication: General Physical Health Deterioration
End date: 2010-09-30
Other drugs received by patient possibly interacting with the suspect drug:
Effexor
Indication: Depression
End date: 2010-09-23
Effexor
Administration route: Oral
Start date: 2010-09-24
End date: 2010-09-28
Metoclopramide Hydrochloride
Administration route: Oral
Indication: General Physical Health Deterioration
Start date: 2010-09-24
End date: 2010-09-30
Effexor
Administration route: Oral
Start date: 2010-09-29
Other drugs received by patient: Nexium; Oxazepam; Fluticasone Propionate/salmeterol
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