ADVERSE REACTIONS
The following adverse events were observed and have been reported in patients using propranolol.
Cardiovascular: Bradycardia; congestive heart failure; intensification of AV block; hypotension; paresthesia of hands; thrombocytopenic purpura; arterial insufficiency, usually of the Raynaud type.
Central Nervous System: Light-headedness, mental depression manifested by insomnia, lassitude, weakness, fatigue; catatonia; visual disturbances; hallucinations; vivid dreams; an acute reversible syndrome characterized by disorientation for time and place, short-term memory loss, emotional lability, slightly clouded sensorium, and decreased performance on neuropsychometrics. For immediate-release formulations, fatigue, lethargy, and vivid dreams appear dose-related.
Gastrointestinal: Nausea, vomiting, epigastric distress, abdominal cramping, diarrhea, constipation, mesenteric arterial thrombosis, ischemic colitis.
Allergic: Hypersensitivity reactions, including anaphylactic/anaphylactoid reactions, pharyngitis and agranulocytosis; erythematous rash, fever combined with aching and sore throat; laryngospasm, and respiratory distress.
Respiratory: Bronchospasm.
Hematologic: Agranulocytosis, nonthrombocytopenic purpura, thrombocytopenic purpura.
Autoimmune: Systemic lupus erythematosus (SLE).
Skin and mucous membranes: Stevens-Johnson Syndrome, toxic epidermal necrolysis, dry eyes, exfoliative dermatitis, erythema multiforme, urticaria, alopecia, SLE-like reactions, and psoriasiform rashes. Oculomucocutaneous syndrome involving the skin, serous membranes and conjunctivae reported for a beta blocker (practolol) have not been associated with propranolol.
Genitourinary: Male impotence; Peyronie's disease.
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REPORTS OF SIDE EFFECTS / ADVERSE REACTIONS RELATED TO INDERAL
Below is a sample of reports where side effects / adverse reactions may be related to Inderal. The information is not vetted and should not be cosidered as verified clinical evidence.
Possible Inderal side effects / adverse reactions in 70 year old male
Reported by a individual with unspecified qualification from United Kingdom on 2007-01-05
Patient: 70 year old male
Reactions: Thrombotic Stroke, Thrombocytopenia
Adverse event resulted in: death, hospitalization
Suspect drug(s):
Inderal
Dosage: 80 mg 1x per 1 day
Administration route: Oral
Indication: Hypertension
Start date: 2001-01-01
End date: 2006-10-05
Lansoprazole
Dosage: 15 mg 1x per 1 day
Administration route: Oral
Start date: 2001-01-01
End date: 2006-10-05
Other drugs received by patient: Cetirizine (Cetirizine); Thiamine (Thiamine); Vitamin B (Vitamin B); Ascorbic Acid
Possible Inderal side effects / adverse reactions in 70 year old male
Reported by a individual with unspecified qualification from United Kingdom on 2007-01-16
Patient: 70 year old male
Reactions: Thrombotic Stroke, Thrombocytopenia
Adverse event resulted in: death, life threatening event, hospitalization
Suspect drug(s):
Inderal
Dosage: 80 mg 1x per 1 day oral
Administration route: Oral
Indication: Hypertension
Start date: 2001-01-01
End date: 2006-10-05
Lansoprazole
Dosage: 15 mg 1x per 1 day oral
Administration route: Oral
Indication: Barrett's Oesophagus
Start date: 2001-01-01
End date: 2006-10-05
Other drugs received by patient: Cetirizine (Cetirizine); Thiamine (Thiamine); Vitamin B (Vitamin B); Ascorbic Acid (Ascorib Acid)
Possible Inderal side effects / adverse reactions in 43 year old female
Reported by a physician from Japan on 2007-02-26
Patient: 43 year old female
Reactions: Head Injury, Fall, Loss of Consciousness
Adverse event resulted in: hospitalization
Suspect drug(s):
Paxil
Dosage: 20mg per day
Administration route: Oral
Indication: Depression
Start date: 2005-06-03
End date: 2006-11-16
Inderal
Dosage: 20mg per day
Administration route: Oral
Indication: Depression
Start date: 2006-09-04
End date: 2006-12-04
Other drugs received by patient: Risperdal; Tryptanol; Sertraline Hydrochloride
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