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Inderal LA (Propranolol Hydrochloride) - Side Effects and Adverse Reactions



The following adverse events were observed and have been reported in patients using propranolol.

Cardiovascular: Bradycardia; congestive heart failure; intensification of AV block; hypotension; paresthesia of hands; thrombocytopenic purpura; arterial insufficiency, usually of the Raynaud type.

Central Nervous System: Light-headedness; mental depression manifested by insomnia, lassitude, weakness, fatigue; catatonia; visual disturbances; hallucinations; vivid dreams; an acute reversible syndrome characterized by disorientation for time and place, short-term memory loss, emotional lability, slightly clouded sensorium, and decreased performance on neuropsychometrics. For immediate release formulations, fatigue, lethargy, and vivid dreams appear dose related.

Gastrointestinal: Nausea, vomiting, epigastric distress, abdominal cramping, diarrhea, constipation, mesenteric arterial thrombosis, ischemic colitis.

Allergic: Hypersensitivity reactions, including anaphylactic/anaphylactoid reactions; pharyngitis and agranulocytosis; erythematous rash; fever combined with aching and sore throat; laryngospasm; respiratory distress.

Respiratory: Bronchospasm.

Hematologic: Agranulocytosis, nonthrombocytopenic purpura, and thrombocytopenic purpura.

Autoimmune: Systemic lupus erythematosus (SLE).

Skin and mucous membranes: Stevens-Johnson Syndrome, toxic epidermal necrolysis, dry eyes, exfoliative dermatitis, erythema multiforme, urticaria, alopecia, SLE-like reactions, and psoriasisiform rashes. Oculomucocutaneous syndrome involving the skin, serous membranes, and conjunctivae reported for a beta-blocker (practolol) have not been associated with propranolol.

Genitourinary: Male impotence; Peyronie's disease.


Below is a sample of reports where side effects / adverse reactions may be related to Inderal LA. The information is not vetted and should not be considered as verified clinical evidence.

Possible Inderal LA side effects / adverse reactions in 43 year old male

Reported by a physician from Switzerland on 2011-10-26

Patient: 43 year old male

Reactions: Confusional State, Hallucination, Visual, Drug Prescribing Error

Adverse event resulted in: hospitalization

Suspect drug(s):
    Dosage: unk

Inderal LA
    Dosage: 80 mg, 1x/day
    Administration route: Oral
    Start date: 2011-09-02
    End date: 2011-09-05

Inderal LA
    Dosage: more than 80 mg
    Administration route: Oral
    Start date: 2011-09-05
    End date: 2011-09-05

Inderal LA
    Dosage: gradually increased to 80 mg daily
    Administration route: Oral
    Start date: 2011-08-29
    End date: 2011-09-02

Inderal LA
    Dosage: 5 mg, 3x/day
    Administration route: Oral
    Indication: Hepatitis
    Start date: 2011-08-20
    End date: 2011-08-29

Other drugs received by patient: Clonazepam; Ketalgin; Risperdal; Tazobac

Possible Inderal LA side effects / adverse reactions in 55 year old male

Reported by a physician from United States on 2012-01-25

Patient: 55 year old male weighing 199.6 kg (439.1 pounds)

Reactions: Peyronie's Disease, Dyspnoea, Skin Exfoliation, Chills, Extrasystoles, Skin Burning Sensation, Pyrexia, Weight Increased, Middle Insomnia, Heart Rate Decreased, Painful Erection, Blister

Suspect drug(s):
Inderal LA

Other drugs received by patient: Propranolol

Possible Inderal LA side effects / adverse reactions in 76 year old female

Reported by a consumer/non-health professional from United States on 2012-08-17

Patient: 76 year old female weighing 68.9 kg (151.7 pounds)

Reactions: Joint Swelling, Hypertension

Suspect drug(s):
    Dosage: 5 mg, daily
    Indication: Hypertension

    Dosage: 100 mg, daily
    Indication: Hypertension

Inderal LA
    Dosage: 160 mg, daily
    Indication: Hypertension

    Dosage: 8 mg, daily
    Indication: Hypertonic Bladder
    Start date: 2012-01-01

Other drugs received by patient: Vitamin D

See index of all Inderal LA side effect reports >>

Drug label data at the top of this Page last updated: 2008-01-15

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