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Inderal LA (Propranolol Hydrochloride) - Summary

 

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INDERAL LA SUMMARY

Inderal (propranolol hydrochloride) is a synthetic beta-adrenergic receptor-blocking agent chemically described as 2-Propanol, 1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-, hydrochloride.

Hypertension

Inderal LA is indicated in the management of hypertension; it may be used alone or used in combination with other antihypertensive agents, particularly a thiazide diuretic. Inderal LA is not indicated in the management of hypertensive emergencies.

Angina Pectoris Due to Coronary Atherosclerosis

Inderal LA is indicated for the long-term management of patients with angina pectoris.

Migraine

Inderal LA is indicated for the prophylaxis of common migraine headache. The efficacy of propranolol in the treatment of a migraine attack that has started has not been established, and propranolol is not indicated for such use.

Hypertrophic Subaortic Stenosis

Inderal LA is useful in the management of hypertrophic subaortic stenosis, especially for treatment of exertional or other stress-induced angina, palpitations, and syncope. Inderal LA also improves exercise performance. The effectiveness of propranolol hydrochloride in this disease appears to be due to a reduction of the elevated outflow pressure gradient, which is exacerbated by beta-receptor stimulation. Clinical improvement may be temporary.

INDERAL LA NEWS HIGHLIGHTS

Published Studies Related to Inderal LA (Propranolol)

A comparison between the effect of oxytocin only and oxytocin plus propranolol on the labor (a double blind randomized trial). [2008.06]

Irbesartan plus low-dose propranolol versus low-dose propranolol alone in cirrhosis: a placebo-controlled, double-blind study. [2008.05]

Effect of post-retrieval propranolol on psychophysiologic responding during subsequent script-driven traumatic imagery in post-traumatic stress disorder. [2008.05]

Hemodynamic effects of propranolol with spironolactone in patients with variceal bleeds: A randomized controlled trial. [2008.03.28]

Octreotide enhances portal pressure reduction induced by propranolol in cirrhosis: a randomized, controlled trial. [2007.10]

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Clinical Trials Related to Inderal LA (Propranolol)

Bioavailability Study of Propranolol Under Fasting Conditions [Completed]

Bioavailability Study of Propranolol Under Fed Conditions [Completed]

Effect of Prophylaxy of Amiodarone and Propranolol and Amiodarone With Propranolol in Prevention of Atrial Fibrillation Post Coronary Artery Bypass Graft [Completed]

Food Study of Propranolol Hydrochloride Extended-Release Capsules 160 mg and Inderal® LA Capsules 160 mg [Completed]

Fasting Study of Propranolol Hydrochloride Extended-Release Capsules 160 mg and Inderal® LA Capsules 160 mg [Completed]

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Page last updated: 2008-08-10

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