IMITREX SUMMARY
IMITREX®
(sumatriptan succinate)
Tablets
IMITREX Tablets contain sumatriptan (as the succinate), a selective 5-hydroxytryptamine1 receptor subtype agonist.
IMITREX Tablets are indicated for the acute treatment of migraine attacks with or without aura in adults.
IMITREX Tablets are not intended for the prophylactic therapy of migraine or for use in the management of hemiplegic or basilar migraine (see CONTRAINDICATIONS). Safety and effectiveness of IMITREX Tablets have not been established for cluster headache, which is present in an older, predominantly male population.
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IMITREX NEWS HIGHLIGHTS Media Articles Related to Imitrex (Sumatriptan)
NovaDel Announces Data From Pilot Efficacy Study Comparing Sumatriptan Oral Spray To Imitrex(R) Tablets
Source: Headache / Migraine News From Medical News Today [2008.09.06]
Published Studies Related to Imitrex (Sumatriptan)
Multimechanistic (sumatriptan-naproxen) early intervention for the acute treatment of migraine. [2008.07.08]
Activation of the cortical pain network by soft tactile stimulation after injection of sumatriptan. [2007.12.15]
Sumatriptan for prevention of acute mountain sickness: randomized clinical trial. [2007.09]
Sumatriptan for prevention of acute mountain sickness: Randomized clinical trial. [2007.06.07]
Two double-blind, multicenter, randomized, placebo-controlled, single-dose studies of sumatriptan/naproxen sodium in the acute treatment of migraine: function, productivity, and satisfaction outcomes. [2007.06.07]
Clinical Trials Related to Imitrex (Sumatriptan)
Food Study of Sumatriptan Succinate Tablets 100 mg to Imitrex® Tablets 100 mg [Completed]
Fasting Study of Sumatriptan Succinate Tablets 100 mg to Imitrex® Tablets 100 mg [Completed]
Prochlorperazine vs Imitrex for Acute Migraine in the Emergency Department [Completed]
A Study to Evaluate the Pharmacokinetics and Bioequivalence of Sumatriptan Delivered Via the Intraject System [Completed]
Phase I Study to Compare NP101(Sumatriptan Iontophoretic Transdermal Patch) With Three Formulations of Imitrex® [Completed]
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IMITREX PATIENT REVIEWS / RATINGS / COMMENTSBased on a total of 8 ratings/reviews, Imitrex has an overall score of 8.50. The effectiveness score is 9.25 and the side effect score is 8. The scores are on ten point scale: 10 - best, 1 - worst. Below are selected reviews: the highest, the median and the lowest rated.
| | Imitrex review by 44 year old female patient | | | Rating |
| Overall rating: | |   |
| Effectiveness: | | Considerably Effective |
| Side effects: | | Mild Side Effects | | |
Treatment Info |
| Condition / reason: | | migraine |
| Dosage & duration: | | 100mg taken 3-6/month for the period of 5 years |
| Other conditions: | | peri-menopause |
| Other drugs taken: | | nsaids | | |
Reported Results |
| Benefits: | | the only complete relief from one sided headache and nausea |
| Side effects: | | slight fatigue occasional tachycardia |
| Comments: | | I was prescribed 100mg dosage pills, which are about the same price ($15/pill) as 50 mg. Taking a whole pill gave me relief but also a light headed sensation and odd heartbeat. I bit the pills in two to take approx. 50mg. Gradually my system became inured to it's effects and I had to take the whole pill, also occasionally it just doesn't work anymore. I have long lasting recurring headaches and have always been worried about overuse and rebound headaches, but so far, so good. |
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| | Imitrex review by 54 year old female patient | | | Rating |
| Overall rating: | | |
| Effectiveness: | | Highly Effective |
| Side effects: | | Mild Side Effects | | |
Treatment Info |
| Condition / reason: | | migraine headaches |
| Dosage & duration: | | 50mg taken apprx. 5 times a month for the period of 9 years |
| Other conditions: | | none |
| Other drugs taken: | | none | | |
Reported Results |
| Benefits: | | This drug has changed my life. I have had severe headaches most of my adult life- Imitrex takes the headaches away. The only downside is that the drug causes me to be a bit drousy. |
| Side effects: | | See above |
| Comments: | | I take the drug at the onset of a headache. Within 10 minutes, the headache symptoms disappear |
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| | Imitrex review by 39 year old female patient | | | Rating |
| Overall rating: | | |
| Effectiveness: | | Moderately Effective |
| Side effects: | | Severe Side Effects | | |
Treatment Info |
| Condition / reason: | | migraines |
| Dosage & duration: | | 1 tablet (100mg) taken as needed for the period of 3 times |
| Other conditions: | | none |
| Other drugs taken: | | none | | |
Reported Results |
| Benefits: | | I initially switched over from Axert since my insurance covers more of the Imitrex prescription. Imitrex just isn't right for me. I experienced almost all of the side effects such as flushing, sensations of tingling/prickling, weakness, drowsiness, dizziness, and fast/pounding heartbeat. On top of that the packaging is just HORRIBLE! It comes 9 to a package. The packaging is a tri-fold "booklet" that is very rigid and has individual blisters for each tablet. It's about 6 1/2 by 3 1/2 inches, folded. I like to have migraine meds on me at all times so I ended up cutting the tablets out of the booklet so they would fit in my wallet or purse. Definitely going back to Axert! |
| Side effects: | | flushing, tingling, prickling, weakness, drowsiness, dizziness and pounding heartbeat. |
| Comments: | | Take 1 tablet by mouth. Max 2 tabs per 24 hours. |
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Page last updated: 2008-09-06
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