Ifex (Ifosfamide / Mesna) - Summary

IFEX SUMMARY

IFEX^® (ifosfamide for injection) single-dose vials for constitution and administration by intravenous infusion each contain 1 gram or 3 grams of sterile ifosfamide.

IFEX, used in combination with certain other approved antineoplastic agents, is indicated for third line chemotherapy of germ cell testicular cancer. It should ordinarily be used in combination with a prophylactic agent for hemorrhagic cystitis, such as mesna.

IFEX NEWS HIGHLIGHTS

Media Articles Related to Ifex (Ifosfamide / Mesna)

Testicular Cancer Signs and Symptoms
Source: MedicineNet Testicular Cancer Specialty [2008.02.01]

Testicular Cancer: A Second Chance
Source: MedicineNet Testicular Cancer Specialty [2007.07.26]

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Published Studies Related to Ifex (Ifosfamide / Mesna)

Comparative pharmacokinetics of oral and intravenous ifosfamide/mesna/methylene blue therapy. [1998.09]

Oral ifosfamide/mesna versus intravenous ifosfamide/mesna in non-small-cell lung cancer: a randomized phase II trial of the EORTC lung cancer cooperative group. [1996.08]

Phase II evaluation of ifosfamide/mesna in metastatic prostate cancer. A Southwest Oncology Group study. [1996.08]

A randomized phase II study of ifosfamide/mesna/cisplatin plus G-CSF or etoposide/cisplatin plus G-CSF in advanced non-small cell lung cancer: a Cancer and Leukemia Group B study. [1996.06]

A pilot study of cisplatin, ifosfamide and mesna in the treatment of malignant mixed mesodermal tumors of the ovary. [2007.05]

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Clinical Trials Related to Ifex (Ifosfamide / Mesna)

Cisplatin and Ifosfamide Combined With Either Paclitaxel or Vinblastine in Treating Men With Progressive or Recurrent Metastatic Germ Cell Tumors [Completed]

Ifosfamide With or Without Paclitaxel in Treating Patients With Advanced, Refractory, or Recurrent Cancer of the Uterus [Active, not recruiting]

Ifosfamide With or Without O(6)-Benzylguanine in Treating Patients With Unresectable, Metastatic Solid Tumors [Completed]

Paclitaxel, Ifosfamide, and Carboplatin Followed By Autologous Stem Cell Transplant in Treating Patients With Germ Cell Tumors That Did Not Respond to Cisplatin [Recruiting]

Bortezomib, Ifosfamide, and Vinorelbine in Treating Young Patients With Hodgkin's Lymphoma That is Recurrent or Did Not Respond to Previous Therapy [Suspended]

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