Each gram of Hytone® (hydrocortisone) Cream 2½% contains 25 mg of hydrocortisone in a water-washable base of purified water, propylene glycol, glyceryl monostearate SE, cholesterol and related sterols, isopropyl myristate, polysorbate 60, cetyl alcohol, sorbitan monostearate, polyoxyl 40 stearate and sorbic acid. Each mL of Hytone (hydrocortisone) Lotion 2½% contains 25 mg of hydrocortisone in a vehicle consisting of carbomer 940, propylene glycol, polysorbate 40, propylene glycol stearate, cholesterol and related sterols, isopropyl myristate, sorbitan palmitate, cetyl alcohol, triethanolamine, sorbic acid, simethicone, and purified water.
Topical corticosteroids are indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Media Articles Related to Hytone ( Topical)
FDA Approves 1st Topical Gel to Ease Redness of Rosacea
Source: MedicineNet brimonidine Specialty [2013.08.28]
Title: FDA Approves 1st Topical Gel to Ease Redness of Rosacea
Category: Health News
Created: 8/27/2013 12:35:00 PM
Last Editorial Review: 8/28/2013 12:00:00 AM
Burn Risk Seen with Topical Pain Relievers
Source: MedPage Today Product Alert [2012.09.13]
WASHINGTON -- The FDA warned Thursday of the risks of rare but serious chemical burns with certain over-the-counter topical pain relievers, including Bengay, Capzasin, Flexall, Icy Hot, and Mentholatum.
Improved treatment for dermatitis in cancer patients
Source: Dermatology News From Medical News Today [2014.12.11]
Researchers have shown how a topical steroid cream frequently used to treat common skin conditions, can be used to improve dermatitis in cancer patients.
Make the Diagnosis: Spotty Hands
Source: MedPage Today Dermatology [2014.11.24]
(MedPage Today) -- A 32-year woman patient presents for evaluation of a persistent eruption on her dorsal hands. She notes the lesions have been present, stable, for a few years, with minimal expansion and rare new lesions. She has tried over-the-counter topical corticosteroids and antifungals without relief.
The rash is almost entirely asymptomatic, with very rare pruritus
She denies oral lesions, joint pain, or systemic symptoms including no fever, cough, or ocular symptoms
On exam, the patient has involvement of the dorsal hands, as shown.
The effectiveness of microbicides that target HIV directly impaired by semen
Source: Sexual Health / STDs News From Medical News Today [2014.11.15]
In the fight against HIV, microbicides - chemical compounds that can be applied topically to the female genital tract to protect against sexually transmitted infections - have been touted as an...
Published Studies Related to Hytone ( Topical)
Effectiveness of topical curcumin for treatment of mastitis in breastfeeding
women: a randomized, double-blind, placebo-controlled clinical trial. 
inflammation in women suffering from lactational mastitis... CONCLUSION: The results of the current study indicate that topical preparation of
"Coffee plus honey" versus "topical steroid" in the treatment of
chemotherapy-induced oral mucositis: a randomised controlled trial. 
steroid, honey, honey plus coffee) in patients suffering from oral mucositis... CONCLUSION: Oral mucositis can be successfully treated by a combination of honey
Topical tetracaine used for 24 hours is safe and rated highly effective by
patients for the treatment of pain caused by corneal abrasions: a double-blind,
randomized clinical trial. 
of pain caused by corneal abrasions... CONCLUSIONS: Topical tetracaine used for 24 hours is safe, and while there was no
Efficacy and safety of topical Trikatu preparation in, relieving mosquito bite
reactions: a randomized controlled trial. 
mosquito bite reactions... CONCLUSION: Trikatu did not show additional effects for relieving mosquito bite
A phase III randomized, placebo-controlled study of topical amitriptyline and
ketamine for chemotherapy-induced peripheral neuropathy (CIPN): a University of
Rochester CCOP study of 462 cancer survivors. 
efficacy of 2% ketamine plus 4% amitriptyline (KA) cream for reducing CIPN... CONCLUSIONS: This study suggests that KA cream does not decrease CIPN symptoms in
Clinical Trials Related to Hytone ( Topical)
Adherence to Topical Hydrocortisone 17-Butyrate 0.1% (LocoidŽ) Using Different Vehicles in Adults With Atopic Dermatitis [Active, not recruiting]
The purpose of this research study is to better understand how the study drug Locoid works
when people use it to treat atopic dermatitis.
Contribution of Salivary Cortisol in the Detection of Infra-clinic Cortisol Adenoma (ACIC) [Recruiting]
Pharmacokinetics of Hydrocortisone After Subcutaneous Administration in Chronic Adrenal Insufficiency [Not yet recruiting]
Patients with chronic adrenal insufficiency need to adapt their hydrocortisone replacement
dose in conditions of physical or psychological stress to prevent life threatening adrenal
crisis. In cases of more severe impairment or unsecure gastrointestinal absorption (e. g.
gastroenteritis, severe infectious disease), parenteral administration of the hydrocortisone
dose is crucial. The study is conducted to offer patients the possibility to perform
hydrocortisone self administration in emergency situations in a way of administration which
is easy to perform and accepted by the patient. Therefore, pharmacokinetics and safety of
subcutaneous hydrocortisone administration will be studied and compared to intramuscular
Trial of Hydrocortisone for Post-Traumatic Stress Disorder (PTSD) [Recruiting]
Developing novel and effective pharmacologic interventions for this post-traumatic stress
disorder is important. The investigators propose to replicate findings of an earlier
published pilot study using low dose hydrocortisone as a treatment for PTSD. In order to do
so in a more meaningful way, the investigators will conduct a larger but similar randomized
double-blind placebo-controlled, cross-over design treatment study examining the use of low
dose hydrocortisone (or placebo) for 4 weeks in combat veterans suffering from PTSD.
The investigators hypothesize that, as described by Aerni et al. (2004), administration of
daily hydrocortisone will lead to a reduction in PTSD symptom severity, but particularly for
re-experiencing types (e. g., flashbacks, nightmares)of symptoms. The investigators also hope
to examine potential predictors and moderators of treatment response based on subjects'
clinical characteristics, as well as serum cortisol and ACTH levels.
Hydrocortisone Replacement in Patients With Secondary Adrenal Insufficiency (SUPREME CORT) [Recruiting]
The aim of this study is to investigate whether a physiologically low hydrocortisone (HC)
dose is better for cognition as compared to a physiologically high HC dose. In addition,
quality of life, metabolic profile and somatosensation will be described in relation to HC
Page last updated: 2014-12-11